Welcome to DrugBank 4.0! If you prefer, you can still go back to version 3.0.
NameProthrombin
Kindprotein
OrganismHuman
Polypeptides
NameUniProt ID
ProthrombinP00734 Details

Drugs

DrugBank IDNameDrug groupPharmacological action?ActionsDetails
DB00001LepirudinapprovedyesinhibitorDetails
DB00006Bivalirudinapproved, investigationalyesinhibitorDetails
DB00278Argatrobanapproved, investigationalyesinhibitorDetails
DB00170Menadioneapproved, nutraceuticalunknownactivatorDetails
DB01123Proflavineapprovednoother/unknownDetails
DB02351HirulogexperimentalunknowninhibitorDetails
DB027234-Oxo-2-Phenylmethanesulfonyl-Octahydro-Pyrrolo[1,2-a]Pyrazine-6-Carboxylic Acid [1-(N-Hydroxycarbamimidoyl)-Piperidin-4-Ylmethyl]-AmideexperimentalunknownDetails
DB03847Gamma-Carboxy-Glutamic AcidexperimentalunknownDetails
DB04136LysophosphotidylserineexperimentalunknownDetails
DB00055Drotrecogin alfaapproved, investigational, withdrawnunknownDetails
DB00100Coagulation Factor IXapprovedunknownDetails
DB04898Ximelagatranapproved, investigational, withdrawnyesinhibitorDetails
DB04591N-{2,2-DIFLUORO-2-[(2R)-PIPERIDIN-2-YL]ETHYL}-2-[2-(1H-1,2,4-TRIAZOL-1-YL)BENZYL][1,3]OXAZOLO[4,5-C]PYRIDIN-4-AMINEexperimentalunknownDetails
DB04697TRANS-4-(GUANIDINOMETHYL)-CYCLOHEXANE-L-YL-D-3-CYCLOHEXYLALANYL-L-AZETIDINE-2-YL-D-TYROSINYL-L-HOMOARGININAMIDEexperimentalunknownDetails
DB047222-(3-CHLORO-6-{[2,2-DIFLUORO-2-(1-OXIDOPYRIDIN-2-YL)ETHYL]AMINO}-1-OXIDOPYRIDIN-2-YL)-N-[1-(3-CHLOROPHENYL)ETHYL]ACETAMIDEexperimentalunknownDetails
DB047711-GUANIDINO-4-(N-NITRO-BENZOYLAMINO-L-LEUCYL-L-PROLYLAMINO)BUTANEexperimentalunknownDetails
DB047721-GUANIDINO-4-(N-PHENYLMETHANESULFONYL-L-LEUCYL-L-PROLYLAMINO)BUTANEexperimentalunknownDetails
DB04786SuraminapprovedunknowninhibitorDetails
DB05777ART-123approved, investigationalunknownDetails
DB05714FlovagatraninvestigationalunknownDetails
DB06695Dabigatran etexilateapprovedyesinhibitorDetails
DB06838methyl L-phenylalaninateexperimentalunknownDetails
DB06841D-phenylalanyl-N-[(1S)-4-{[amino(iminio)methyl]amino}-1-(chloroacetyl)butyl]-L-prolinamideexperimentalunknownDetails
DB06845(S)-N-(4-carbamimidoylbenzyl)-1-(2-(cyclopentylamino)ethanoyl)pyrrolidine-2-carboxamideexperimentalunknownDetails
DB06850(S)-N-(4-carbamimidoylbenzyl)-1-(2-(cyclohexylamino)ethanoyl)pyrrolidine-2-carboxamideexperimentalunknownDetails
DB06853N-cycloheptylglycyl-N-(4-carbamimidoylbenzyl)-L-prolinamideexperimentalunknownDetails
DB068542-(2-HYDROXY-BIPHENYL)-1H-BENZOIMIDAZOLE-5-CARBOXAMIDINEexperimentalunknownDetails
DB038656-Chloro-2-(2-Hydroxy-Biphenyl-3-Yl)-1h-Indole-5-CarboxamidineexperimentalunknownDetails
DB06858N-cyclooctylglycyl-N-(4-carbamimidoylbenzyl)-L-prolinamideexperimentalunknownDetails
DB06859N-ALLYL-5-AMIDINOAMINOOXY-PROPYLOXY-3-CHLORO-N-CYCLOPENTYLBENZAMIDEexperimentalunknownDetails
DB068616-(2-HYDROXY-CYCLOPENTYL)-7-OXO-HEPTANAMIDINEexperimentalunknownDetails
DB068656-CARBAMIMIDOYL-2-[2-HYDROXY-6-(4-HYDROXY-PHENYL)-INDAN-1-YL]-HEXANOIC ACIDexperimentalunknownDetails
DB068666-CARBAMIMIDOYL-2-[2-HYDROXY-5-(3-METHOXY-PHENYL)-INDAN-1-YL]-HEXANOIC ACIDexperimentalunknownDetails
DB06868N-(3-chlorobenzyl)-1-(4-methylpentanoyl)-L-prolinamideexperimentalunknownDetails
DB068691-[2-AMINO-2-CYCLOHEXYL-ACETYL]-PYRROLIDINE-3-CARBOXYLIC ACID 5-CHLORO-2-(2-ETHYLCARBAMOYL-ETHOXY)-BENZYLAMIDEexperimentalunknownDetails
DB068781-[(2R)-2-aminobutanoyl]-N-(3-chlorobenzyl)-L-prolinamideexperimentalunknownDetails
DB06911D-leucyl-N-(3-chlorobenzyl)-L-prolinamideexperimentalunknownDetails
DB06919D-phenylalanyl-N-(3-chlorobenzyl)-L-prolinamideexperimentalunknownDetails
DB069291-butanoyl-N-(4-carbamimidoylbenzyl)-L-prolinamideexperimentalunknownDetails
DB06936N-(4-carbamimidoylbenzyl)-1-(4-methylpentanoyl)-L-prolinamideexperimentalunknownDetails
DB06942N-(4-carbamimidoylbenzyl)-1-(3-phenylpropanoyl)-L-prolinamideexperimentalunknownDetails
DB069471-[(2R)-2-aminobutanoyl]-N-(4-carbamimidoylbenzyl)-L-prolinamideexperimentalunknownDetails
DB06996D-leucyl-N-(4-carbamimidoylbenzyl)-L-prolinamideexperimentalunknownDetails
DB07005D-phenylalanyl-N-{4-[amino(iminio)methyl]benzyl}-L-prolinamideexperimentalunknownDetails
DB07016(3R)-8-(dioxidosulfanyl)-3-methyl-1,2,3,4-tetrahydroquinolineexperimentalunknownDetails
DB07027D-phenylalanyl-N-(3-fluorobenzyl)-L-prolinamideexperimentalunknownDetails
DB07083beta-phenyl-D-phenylalanyl-N-propyl-L-prolinamideexperimentalunknownDetails
DB07088(S)-N-(4-carbamimidoylbenzyl)-1-(2-(cyclopentyloxy)ethanoyl)pyrrolidine-2-carboxamideexperimentalunknownDetails
DB07091(S)-N-(4-carbamimidoylbenzyl)-1-(2-(cyclohexyloxy)ethanoyl)pyrrolidine-2-carboxamideexperimentalunknownDetails
DB07095(S)-N-(4-carbamimidoylbenzyl)-1-(3-cyclopentylpropanoyl)pyrrolidine-2-carboxamideexperimentalunknownDetails
DB071052-[2-(4-CHLORO-PHENYLSULFANYL)-ACETYLAMINO]-3-(4-GUANIDINO-PHENYL)-PROPIONAMIDEexperimentalunknownDetails
DB07120N4-(N,N-DIPHENYLCARBAMOYL)-AMINOGUANIDINEexperimentalunknownDetails
DB07128N7-BUTYL-N2-(5-CHLORO-2-METHYLPHENYL)-5-METHYL[1,2,4]TRIAZOLO[1,5-A]PYRIMIDINE-2,7-DIAMINEexperimentalunknownDetails
DB07131(S)-N-(4-carbamimidoylbenzyl)-1-(3-cyclohexylpropanoyl)pyrrolidine-2-carboxamideexperimentalunknownDetails
DB07133D-phenylalanyl-N-(3-methylbenzyl)-L-prolinamideexperimentalunknownDetails
DB07143D-phenylalanyl-N-benzyl-L-prolinamideexperimentalunknownDetails
DB07165N-(5-CHLORO-BENZO[B]THIOPHEN-3-YLMETHYL)-2-[6-CHLORO-OXO-3-(2-PYRIDIN-2-YL-ETHYLAMINO)-2H-PYRAZIN-1-YL]-ACETAMIDEexperimentalunknownDetails
DB071903-cyclohexyl-D-alanyl-N-(3-chlorobenzyl)-L-prolinamideexperimentalunknownDetails
DB03159CRA_8696experimentalunknownDetails
DB07211(2R)-2-(5-CHLORO-2-THIENYL)-N-{(3S)-1-[(1S)-1-METHYL-2-MORPHOLIN-4-YL-2-OXOETHYL]-2-OXOPYRROLIDIN-3-YL}PROPENE-1-SULFONAMIDEexperimentalunknownDetails
DB072772-(5-CHLORO-2-THIENYL)-N-{(3S)-1-[(1S)-1-METHYL-2-MORPHOLIN-4-YL-2-OXOETHYL]-2-OXOPYRROLIDIN-3-YL}ETHANESULFONAMIDEexperimentalunknownDetails
DB072782-(5-CHLORO-2-THIENYL)-N-{(3S)-1-[(1S)-1-METHYL-2-MORPHOLIN-4-YL-2-OXOETHYL]-2-OXOPYRROLIDIN-3-YL}ETHENESULFONAMIDEexperimentalunknownDetails
DB07279N-ETHYL-N-ISOPROPYL-3-METHYL-5-{[(2S)-2-(PYRIDIN-4-YLAMINO)PROPYL]OXY}BENZAMIDEexperimentalunknownDetails
DB073534-(2,5-DIAMINO-5-HYDROXY-PENTYL)-PHENOLexperimentalunknownDetails
DB073662-[N'-(4-AMINO-BUTYL)-HYDRAZINOCARBONYL]-PYRROLIDINE-1-CARBOXYLIC ACID BENZYL ESTERexperimentalunknownDetails
DB073765-(DIMETHYLAMINO)-1-NAPHTHALENESULFONIC ACID(DANSYL ACID)experimentalunknownDetails
DB074001-ETHOXYCARBONYL-D-PHE-PRO-2(4-AMINOBUTYL)HYDRAZINEexperimentalunknownDetails
DB01767Hemi-BabimexperimentalunknownDetails
DB074404-TERT-BUTYLBENZENESULFONIC ACIDexperimentalunknownDetails
DB074613-AMINO-3-BENZYL-9-CARBOXAMIDE[4.3.0]BICYCLO-1,6-DIAZANONAN-2-ONEexperimentalunknownDetails
DB021932-(2-Hydroxy-Phenyl)-1h-Benzoimidazole-5-CarboxamidineexperimentalunknownDetails
DB075084-(5-BENZENESULFONYLAMINO-1-METHYL-1H-BENZOIMIDAZOL-2-YLMETHYL)-BENZAMIDINEexperimentalunknownDetails
DB075151-(2-{[(6-AMINO-2-METHYLPYRIDIN-3-YL)METHYL]AMINO}ETHYL)-6-CHLORO-3-[(2,2-DIFLUORO-2-PYRIDIN-2-YLETHYL)AMINO]-1,4-DIHYDROPYRAZIN-2-OLexperimentalunknownDetails
DB075216-CHLORO-1-(2-{[(5-CHLORO-1-BENZOTHIEN-3-YL)METHYL]AMINO}ETHYL)-3-[(2-PYRIDIN-2-YLETHYL)AMINO]-1,4-DIHYDROPYRAZIN-2-OLexperimentalunknownDetails
DB07522N-[(2R,3S)-3-AMINO-2-HYDROXY-4-PHENYLBUTYL]NAPHTHALENE-2-SULFONAMIDEexperimentalunknownDetails
DB07527N-[(2R,3S)-3-AMINO-2-HYDROXY-4-PHENYLBUTYL]-4-METHOXY-2,3,6-TRIMETHYLBENZENESULFONAMIDEexperimentalunknownDetails
DB075482-(6-CHLORO-3-{[2,2-DIFLUORO-2-(2-PYRIDINYL)ETHYL]AMINO}-2-OXO-1(2H)-PYRAZINYL)-N-[(2-FLUORO-6-PYRIDINYL)METHYL]ACETAMIDEexperimentalunknownDetails
DB075492-(6-CHLORO-3-{[2,2-DIFLUORO-2-(2-PYRIDINYL)ETHYL]AMINO}-2-OXO-1(2H)-PYRAZINYL)-N-[(2-FLUORO-3-METHYL-6-PYRIDINYL)METHYL]ACETAMIDEexperimentalunknownDetails
DB075502-(6-CHLORO-3-{[2,2-DIFLUORO-2-(1-OXIDO-2-PYRIDINYL)ETHYL]AMINO}-2-OXO-1(2H)-PYRAZINYL)-N-[(2-FLUOROPHENYL)METHYL]ACETAMIDEexperimentalunknownDetails
DB076393-(7-DIAMINOMETHYL-NAPHTHALEN-2-YL)-PROPIONIC ACID ETHYL ESTERexperimentalunknownDetails
DB07658AC-(D)PHE-PRO-BOROLYS-OHexperimentalunknownDetails
DB07659AC-(D)PHE-PRO-BOROHOMOLYS-OHexperimentalunknownDetails
DB07660AC-(D)PHE-PRO-BOROHOMOORNITHINE-OHexperimentalunknownDetails
DB07665N-[2-(carbamimidamidooxy)ethyl]-2-{6-cyano-3-[(2,2-difluoro-2-pyridin-2-ylethyl)amino]-2-fluorophenyl}acetamideexperimentalunknownDetails
DB077183-(4-HYDROXY-PHENYL)PYRUVIC ACIDexperimentalunknownDetails
DB031364-Iodobenzo[B]Thiophene-2-CarboxamidineexperimentalunknownDetails
DB077414-(1R,3AS,4R,8AS,8BR)-[1-DIFLUOROMETHYL-2-(4-FLUOROBENZYL)-3-OXODECAHYDROPYRROLO[3,4-A]PYRROLIZIN-4-YL]BENZAMIDINEexperimentalunknownDetails
DB07796(3ASR,4RS,8ASR,8BRS)-4-(2-(4-FLUOROBENZYL)-1,3-DIOXODEACAHYDROPYRROLO[3,4-A] PYRROLIZIN-4-YL)BENZAMIDINEexperimentalunknownDetails
DB078094-({[4-(3-METHYLBENZOYL)PYRIDIN-2-YL]AMINO}METHYL)BENZENECARBOXIMIDAMIDEexperimentalunknownDetails
DB078971-(HYDROXYMETHYLENEAMINO)-8-HYDROXY-OCTANEexperimentalunknownDetails
DB07934[[CYCLOHEXANESULFONYL-GLYCYL]-3[PYRIDIN-4-YL-AMINOMETHYL]ALANYL]PIPERIDINEexperimentalunknownDetails
DB07944N-{3-METHYL-5-[2-(PYRIDIN-4-YLAMINO)-ETHOXY]-PHENYL}-BENZENESULFONAMIDEexperimentalunknownDetails
DB07946N-[2-({[amino(imino)methyl]amino}oxy)ethyl]-2-{6-chloro-3-[(2,2-difluoro-2-phenylethyl)amino]-2-fluorophenyl}acetamideexperimentalunknownDetails
DB080614-[3-(4-CHLOROPHENYL)-1H-PYRAZOL-5-YL]PIPERIDINEexperimentalunknownDetails
DB080623-(4-CHLOROPHENYL)-5-(METHYLTHIO)-4H-1,2,4-TRIAZOLEexperimentalunknownDetails
DB08152{(2S)-1-[N-(tert-butoxycarbonyl)glycyl]pyrrolidin-2-yl}methyl (3-chlorophenyl)acetateexperimentalunknownDetails
DB08187METHYL-PHE-PRO-AMINO-CYCLOHEXYLGLYCINEexperimentalunknownDetails
DB01766Beta-(2-Naphthyl)-AlanineexperimentalunknownDetails
DB082542-NAPHTHALENESULFONIC ACIDexperimentalunknownDetails
DB08422[PHENYLALANINYL-PROLINYL]-[2-(PYRIDIN-4-YLAMINO)-ETHYL]-AMINEexperimentalunknownDetails
DB085464-[(3AS,4R,7R,8AS,8BR)-2-(1,3-BENZODIOXOL-5-YLMETHYL)-7-HYDROXY-1,3-DIOXODECAHYDROPYRROLO[3,4-A]PYRROLIZIN-4-YL]BENZENECARBOXIMIDAMIDEexperimentalunknownDetails
DB08624BENZOTHIAZOLEexperimentalunknownDetails
DB00025Antihemophilic Factorapproved, investigationalunknownactivatorDetails