Tubulin beta-2 chain

Details

Name
Tubulin beta-2 chain
Synonyms
Not Available
Gene Name
Not Available
Organism
Pig roundworm
Amino acid sequence
>lcl|BSEQ0017540|Tubulin beta-2 chain
MREIVQVQAGQCGNQIGAKFWEVISDEHGIQPDGMYAGESDLQLDRIEVYYNEAHGGKYV
PRCVLVDLEPGTMDSVRAGPYGQLFRPDNFIFGQSGAGNNWAKGHYTEGAELVDQVLDVI
RKEAEGCDCLQGFQLTHSLGGGTGSGMGTLMISKIREEYPDRIMSSFSVVPSPKVSDVVL
EPYNATLSVHQLVENTDETFCIDNEALYDICFRTLKLTNPSYGDLNHLVSMTMSGVTTCL
RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLSARGTAAYRALTVAELTQQVFDAKNMM
AACDPRHGRYLTVAVMFRGRMSMREVDNQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRG
LKMSATFMGNTTAIQELFRRISEQFNAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLIS
EYQQYQEATIEEEGEFEDSHNIQHDDYSREEEQEE
Number of residues
455
Molecular Weight
51336.46
Theoretical pI
Not Available
GO Classification
Functions
GTP binding / GTPase activity / structural constituent of cytoskeleton
Processes
microtubule-based process
Components
cytoplasm / microtubule
General Function
Structural constituent of cytoskeleton
Specific Function
Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.
Pfam Domain Function
Transmembrane Regions
Not Available
Cellular Location
Cytoplasm
Chromosome Location
Not Available
Locus
Not Available
External Identifiers
ResourceLink
UniProtKB IDF1L7U3
UniProtKB Entry NameF1L7U3_ASCSU
General References
  1. Wang J, Czech B, Crunk A, Wallace A, Mitreva M, Hannon GJ, Davis RE: Deep small RNA sequencing from the nematode Ascaris reveals conservation, functional diversification, and novel developmental profiles. Genome Res. 2011 Sep;21(9):1462-77. doi: 10.1101/gr.121426.111. Epub 2011 Jun 17. [Article]

Drug Relations

Drug Relations
DrugBank IDNameDrug groupPharmacological action?ActionsDetails
DB00518Albendazoleapproved, vet_approvedyesinhibitorDetails