NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial
Details
- Name
- NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial
- Synonyms
- CI-ASHI
- Complex I-ASHI
- NADH-ubiquinone oxidoreductase ASHI subunit
- Gene Name
- NDUFB8
- Organism
- Humans
- Amino acid sequence
>lcl|BSEQ0001348|NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial MAVARAGVLGVQWLQRASRNVMPLGARTASHMTKDMFPGPYPRTPEERAAAAKKYNMRVE DYEPYPDDGMGYGDYPKLPDRSQHERDPWYSWDQPGLRLNWGEPMHWHLDMYNRNRVDTS PTPVSWHVMCMQLFGFLAFMIFMCWVGDVYPVYQPVGPKQYPYNNLYLERGGDPSKEPER VVHYEI
- Number of residues
- 186
- Molecular Weight
- 21765.665
- Theoretical pI
- 6.79
- GO Classification
- FunctionsNADH dehydrogenase (ubiquinone) activityProcessescellular metabolic process / mitochondrial electron transport, NADH to ubiquinone / respiratory electron transport chain / small molecule metabolic processComponentsendoplasmic reticulum / integral component of membrane / mitochondrial inner membrane / mitochondrial respiratory chain complex I
- General Function
- Nadh dehydrogenase (ubiquinone) activity
- Specific Function
- Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
- Pfam Domain Function
- NDUF_B8 (PF05821)
- Transmembrane Regions
- 133-153
- Cellular Location
- Mitochondrion inner membrane
- Gene sequence
>lcl|BSEQ0018993|NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial (NDUFB8) ATGGCGGTGGCCAGGGCCGGGGTCTTGGGAGTCCAGTGGCTGCAAAGGGCATCCCGGAAC GTGATGCCGCTGGGCGCACGGACAGCCTCCCACATGACCAAGGACATGTTCCCGGGGCCC TATCCTAGGACCCCAGAAGAACGGGCCGCCGCCGCCAAGAAGTATAATATGCGTGTGGAA GACTACGAACCTTACCCGGATGATGGCATGGGGTATGGCGACTACCCGAAGCTCCCTGAC CGCTCACAGCATGAGAGAGATCCATGGTATAGCTGGGACCAGCCGGGCCTGAGGTTGAAC TGGGGTGAACCGATGCACTGGCACCTAGACATGTACAACAGGAACCGTGTGGATACATCC CCCACACCTGTTTCTTGGCATGTCATGTGTATGCAGCTCTTCGGTTTCCTGGCTTTCATG ATATTCATGTGCTGGGTGGGGGACGTGTACCCTGTCTACCAGCCTGTGTGTAGGCACCAC TTCTCTTACAATTTAGGCTTTCTCTCTGCCTTGGGCTGA
- Chromosome Location
- 10
- Locus
- 10q23.2-q23.33
- External Identifiers
Resource Link UniProtKB ID O95169 UniProtKB Entry Name NDUB8_HUMAN GenBank Protein ID 4164448 GenBank Gene ID AF044958 GenAtlas ID NDUFB8 HGNC ID HGNC:7703 - General References
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