Delta-hemolysin
Details
- Name
- Delta-hemolysin
- Synonyms
- Delta-lysin
- Delta-toxin
- Gene Name
- hld
- Organism
- Staphylococcus aureus
- Amino acid sequence
>lcl|BSEQ0007800|Delta-hemolysin MAQDIISTIGDLVKWIIDTVNKFTKK
- Number of residues
- 26
- Molecular Weight
- 2978.515
- Theoretical pI
- 9.37
- GO Classification
- Processeshemolysis by symbiont of host erythrocytesComponentsextracellular region / host cell plasma membrane / integral component of membrane
- General Function
- Not Available
- Specific Function
- Lyses erythrocytes and many other mammalian cells.
- Pfam Domain Function
- Delta_lysin (PF05372)
- Transmembrane Regions
- Not Available
- Cellular Location
- Secreted
- Gene sequence
>lcl|BSEQ0007799|786 bp ATGAAAGTCCAAATTTATCAATTACCGATTGTTTTTGGAGATAGTTCTAAAAATGAAACT CAAATAACGCAATGGTTCGAAAAAAATATGAATGCTGAAGTAGATGTAGTCGTTTTACCT GAAATGTGGAATAATGGCTATGATTTAGAGCATTTAAATGAAAAAGCAGATAATAATCTA GGACAAAGTTTTTCATTTATTAAACATTTAGCTGAAAAATATAAAGTCGATATCGTAGCT GGGTCTGTTTCTAACATTAGAAACAATCAAATATTTAATACAGCTTTTAGTGTGAATAAA AGTGGCCAGCTGATTAATGAATACGACAAAGTTCATTTAGTTCCTATGTTAAGAGAGCAT GAATTTTTAACCGCTGGCGAATACGTAGCTGAACCCTTTCAATTGTCTGACGGTACTTAT GTGACCCAACTTATCTGTTATGATTTACGTTTTCCAGAATTATTAAGATATCCTGCTCGT AGTGGTGCTAAAATTGCATTTTATGTGGCGCAATGGCCTATGTCACGTCTTCAACATTGG CATTCATTACTAAAGGCACGTGCAATTGAAAATAATATGTTTGTCATTGGAACTAATAGC ACTGGATTCGATGGTAACACAGAATATGCTGGTCATTCGATAGTTATAAACCCAAATGGA GATTTAGTTGGAGAATTAAATGAATCCGCAGATATTTTGACTGTAGATTTAAACTTAAAT GAAGTAGAACAGCAACGCGAAAATATACCTGTATTTAAAAGTATTAAATTAGATTTGTAT AAATAA
- Chromosome Location
- Not Available
- Locus
- Not Available
- External Identifiers
Resource Link UniProtKB ID P0C1V1 UniProtKB Entry Name HLD_STAAU GenBank Protein ID 46506 GenBank Gene ID X52543 - General References
- Novick RP, Projan SJ, Kornblum J, Ross HF, Ji G, Kreiswirth B, Vandenesch F, Moghazeh S: The agr P2 operon: an autocatalytic sensory transduction system in Staphylococcus aureus. Mol Gen Genet. 1995 Aug 30;248(4):446-58. [Article]
- Fitton JE, Dell A, Shaw WV: The amino acid sequence of the delta haemolysin of Staphylococcus aureus. FEBS Lett. 1980 Jun 30;115(2):209-12. [Article]
- Raghunathan G, Seetharamulu P, Brooks BR, Guy HR: Models of delta-hemolysin membrane channels and crystal structures. Proteins. 1990;8(3):213-25. [Article]