ADP/ATP translocase 3
Details
- Name
- ADP/ATP translocase 3
- Synonyms
- Adenine nucleotide translocator 3
- ADP,ATP carrier protein 3
- ADP,ATP carrier protein, isoform T2
- ANT 2
- ANT 3
- ANT3
- Solute carrier family 25 member 6
- Gene Name
- SLC25A6
- Organism
- Humans
- Amino acid sequence
>lcl|BSEQ0010434|ADP/ATP translocase 3 MTEQAISFAKDFLAGGIAAAISKTAVAPIERVKLLLQVQHASKQIAADKQYKGIVDCIVR IPKEQGVLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKHTQFWRYFAGNLASG GAAGATSLCFVYPLDFARTRLAADVGKSGTEREFRGLGDCLVKITKSDGIRGLYQGFSVS VQGIIIYRAAYFGVYDTAKGMLPDPKNTHIVVSWMIAQTVTAVAGVVSYPFDTVRRRMMM QSGRKGADIMYTGTVDCWRKIFRDEGGKAFFKGAWSNVLRGMGGAFVLVLYDELKKVI
- Number of residues
- 298
- Molecular Weight
- 32866.025
- Theoretical pI
- 10.26
- GO Classification
- FunctionsATPProcessesactive induction of host immune response by virus / ADP transport / apoptotic process / ATP transport / cellular protein metabolic process / energy reserve metabolic process / modulation by virus of host morphology or physiology / protein targeting to mitochondrion / regulation of insulin secretion / small molecule metabolic process / viral life cycle / viral processComponentsintegral component of membrane / mitochondrial inner membrane / mitochondrial inner membrane presequence translocase complex / mitochondrion / nucleus
- General Function
- Atp:adp antiporter activity
- Specific Function
- Catalyzes the exchange of cytoplasmic ADP with mitochondrial ATP across the mitochondrial inner membrane. May participate in the formation of the permeability transition pore complex (PTPC) responsible for the release of mitochondrial products that triggers apoptosis.
- Pfam Domain Function
- Mito_carr (PF00153)
- Transmembrane Regions
- 5-39 75-100 109-143 176-202 207-241 273-298
- Cellular Location
- Mitochondrion inner membrane
- Gene sequence
>lcl|BSEQ0010435|ADP/ATP translocase 3 (SLC25A6) ATGACGGAACAGGCCATCTCCTTCGCCAAAGACTTCTTGGCCGGAGGCATCGCCGCCGCC ATCTCCAAGACGGCCGTGGCTCCGATCGAGCGGGTCAAGCTGCTGCTGCAGGTCCAGCAC GCCAGCAAGCAGATCGCCGCCGACAAGCAGTACAAGGGCATCGTGGACTGCATTGTCCGC ATCCCCAAGGAGCAGGGCGTGCTGTCCTTCTGGAGGGGCAACCTTGCCAACGTCATTCGC TACTTCCCCACTCAAGCCCTCAACTTCGCCTTCAAGGATAAGTACAAGCAGATCTTCCTG GGGGGCGTGGACAAGCACACGCAGTTCTGGAGGTACTTTGCGGGCAACCTGGCCTCCGGC GGTGCGGCCGGCGCGACCTCCCTCTGCTTCGTGTACCCGCTGGATTTCGCCAGAACCCGC CTGGCAGCGGACGTGGGAAAGTCAGGCACAGAGCGCGAGTTCCGAGGCCTGGGAGACTGC CTGGTGAAGATCACCAAGTCCGACGGCATCCGGGGCCTGTACCAGGGCTTCAGTGTCTCC GTGCAGGGCATCATCATCTACCGGGCGGCCTACTTCGGCGTGTACGATACGGCCAAGGGC ATGCTCCCCGACCCCAAGAACACGCACATCGTGGTGAGCTGGATGATCGCGCAGACCGTG ACGGCCGTGGCCGGCGTGGTGTCCTACCCCTTCGACACGGTGCGGCGGCGCATGATGATG CAGTCCGGGCGCAAAGGAGCTGACATCATGTACACGGGCACCGTCGACTGTTGGAGGAAG ATCTTCAGAGATGAGGGGGGCAAGGCCTTCTTCAAGGGTGCGTGGTCCAACGTCCTGCGG GGCATGGGGGGCGCCTTCGTGCTGGTCCTGTACGACGAGCTCAAGAAGGTGATCTAA
- Chromosome Location
- X, Y
- Locus
- Xp22.32 and Yp11.3
- External Identifiers
Resource Link UniProtKB ID P12236 UniProtKB Entry Name ADT3_HUMAN GenBank Protein ID 339723 GenBank Gene ID J03592 GenAtlas ID SLC25A6 HGNC ID HGNC:10992 - General References
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