Signal recognition particle 14 kDa protein
Details
- Name
- Signal recognition particle 14 kDa protein
- Synonyms
- 18 kDa Alu RNA-binding protein
- SRP14
- Gene Name
- SRP14
- Organism
- Humans
- Amino acid sequence
>lcl|BSEQ0017456|Signal recognition particle 14 kDa protein MVLLESEQFLTELTRLFQKCRTSGSVYITLKKYDGRTKPIPKKGTVEGFEPADNKCLLRA TDGKKKISTVVSSKEVNKFQMAYSNLLRANMDGLKKRDKKNKTKKTKAAAAAAAAAPAAA ATAPTTAATTAATAAQ
- Number of residues
- 136
- Molecular Weight
- 14569.775
- Theoretical pI
- Not Available
- GO Classification
- Functions7S RNA binding / endoplasmic reticulum signal peptide binding / poly(A) RNA binding / RNA bindingProcessescellular protein metabolic process / cotranslational protein targeting to membrane / gene expression / protein targeting to ER / response to drug / SRP-dependent cotranslational protein targeting to membrane / translationComponentscytoplasm / cytosol / extracellular exosome / nucleus / signal recognition particle, endoplasmic reticulum targeting
- General Function
- Rna binding
- Specific Function
- Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding.
- Pfam Domain Function
- SRP14 (PF02290)
- Transmembrane Regions
- Not Available
- Cellular Location
- Cytoplasm
- Chromosome Location
- Not Available
- Locus
- Not Available
- External Identifiers
Resource Link UniProtKB ID P37108 UniProtKB Entry Name SRP14_HUMAN HGNC ID HGNC:11299 - General References
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