Endoglucanase G
Details
- Name
- Endoglucanase G
- Synonyms
- 3.2.1.4
- Cellulase G
- EGCCG
- Endo-1,4-beta-glucanase G
- Gene Name
- celCCG
- Organism
- Clostridium cellulolyticum (strain ATCC 35319 / DSM 5812 / JCM 6584 / H10)
- Amino acid sequence
>lcl|BSEQ0016469|Endoglucanase G MLKTKRKLTKAIGVALSISILSSLVSFIPQTNTYAAGTYNYGEALQKSIMFYEFQRSGDL PADKRDNWRDDSGMKDGSDVGVDLTGGWYDAGDHVKFNLPMSYTSAMLAWSLYEDKDAYD KSGQTKYIMDGIKWANDYFIKCNPTPGVYYYQVGDGGKDHSWWGPAEVMQMERPSFKVDA SKPGSAVCASTAASLASAAVVFKSSDPTYAEKCISHAKNLFDMADKAKSDAGYTAASGYY SSSSFYDDLSWAAVWLYLATNDSTYLDKAESYVPNWGKEQQTDIIAYKWGQCWDDVHYGA ELLLAKLTNKQLYKDSIEMNLDFWTTGVNGTRVSYTPKGLAWLFQWGSLRHATTQAFLAG VYAEWEGCTPSKVSVYKDFLKSQIDYALGSTGRSFVVGYGVNPPQHPHHRTAHGSWTDQM TSPTYHRHTIYGALVGGPDNADGYTDEINNYVNNEIACDYNAGFTGALAKMYKHSGGDPI PNFKAIEKITNDEVIIKAGLNSTGPNYTEIKAVVYNQTGWPARVTDKISFKYFMDLSEIV AAGIDPLSLVTSSNYSEGKNTKVSGVLPWDVSNNVYYVNVDLTGENIYPGGQSACRREVQ FRIAAPQGTTYWNPKNDFSYDGLPTTSTVNTVTNIPVYDNGVKVFGNEPAGGSENPDPEI LYGDVNSDKNVDALDFAALKKYLLGGTSSIDVKAADTYKDGNIDAIDMATLKKYLLGTIT QLPQG
- Number of residues
- 725
- Molecular Weight
- 79775.34
- Theoretical pI
- 5.2
- GO Classification
- Functionscellulase activity / cellulose bindingProcessescellulose catabolic process
- General Function
- Cellulose binding
- Specific Function
- The biological conversion of cellulose to glucose generally requires three types of hydrolytic enzymes: (1) Endoglucanases which cut internal beta-1,4-glucosidic bonds; (2) Exocellobiohydrolases that cut the dissaccharide cellobiose from the non-reducing end of the cellulose polymer chain; (3) Beta-1,4-glucosidases which hydrolyze the cellobiose and other short cello-oligosaccharides to glucose.
- Pfam Domain Function
- Transmembrane Regions
- Not Available
- Cellular Location
- Cytoplasmic
- Gene sequence
>lcl|BSEQ0016470|Endoglucanase G (celCCG) TTGCTTAAGACTAAAAGAAAATTGACAAAAGCAATCGGTGTTGCATTATCGATTTCAATA TTATCTTCGCTAGTATCGTTTATACCTCAAACAAATACATATGCAGCAGGAACATATAAC TATGGAGAAGCATTACAGAAATCAATAATGTTCTATGAATTCCAGCGTTCGGGAGATCTT CCGGCTGATAAACGTGACAACTGGAGAGACGATTCCGGTATGAAAGACGGTTCTGATGTA GGAGTTGATCTTACAGGAGGATGGTACGATGCAGGTGACCATGTGAAATTTAATCTACCT ATGTCATATACATCTGCAATGCTTGCATGGTCCTTATATGAGGATAAGGATGCTTATGAT AAGAGCGGTCAGACAAAATATATAATGGACGGTATAAAATGGGCTAATGATTATTTTATT AAATGTAATCCGACACCCGGTGTATATTATTACCAAGTAGGAGACGGCGGAAAGGACCAC TCTTGGTGGGGCCCTGCGGAAGTAATGCAGATGGAAAGACCGTCTTTTAAGGTTGACGCT TCTAAGCCCGGTTCTGCAGTATGTGCTTCCACTGCAGCTTCTCTGGCATCTGCAGCAGTA GTCTTTAAATCCAGTGATCCTACTTATGCAGAAAAGTGCATAAGCCATGCAAAGAACCTG TTTGATATGGCTGACAAAGCAAAGAGTGATGCTGGTTATACTGCGGCTTCAGGCTACTAC AGCTCAAGCTCATTTTACGATGATCTCTCATGGGCTGCAGTATGGTTATATCTTGCTACA AATGACAGTACATATTTAGACAAAGCAGAATCCTATGTACCGAATTGGGGTAAAGAACAG CAGACAGATATTATCGCCTACAAGTGGGGACAGTGCTGGGATGATGTTCATTATGGTGCT GAGCTTCTTCTTGCAAAGCTTACAAACAAACAATTGTATAAGGATAGTATAGAAATGAAC CTTGACTTCTGGACAACTGGTGTTAACGGAACACGTGTTTCTTACACGCCAAAGGGTTTG GCGTGGCTATTCCAATGGGGTTCATTAAGACATGCTACAACTCAGGCTTTTTTAGCCGGT GTTTATGCAGAGTGGGAAGGCTGTACGCCATCCAAAGTATCTGTATATAAGGATTTCCTC AAGAGTCAAATTGATTATGCACTTGGCAGTACCGGAAGAAGTTTTGTTGTCGGATATGGA GTAAATCCTCCTCAACATCCTCATCACAGAACTGCTCACGGTTCATGGACAGATCAAATG ACTTCACCAACATACCACAGGCATACTATTTATGGTGCGTTGGTAGGAGGACCGGATAAT GCAGATGGCTATACTGATGAAATAAACAATTATGTCAATAATGAAATAGCCTGCGATTAT AATGCCGGATTTACAGGTGCACTTGCAAAAATGTACAAGCATTCTGGCGGAGATCCGATT CCAAACTTCAAGGCTATCGAAAAAATAACCAACGATGAAGTTATTATAAAGGCAGGTTTG AATTCAACTGGCCCTAACTACACTGAAATCAAGGCTGTTGTTTATAACCAGACAGGATGG CCTGCAAGAGTTACGGACAAGATATCATTTAAATATTTTATGGACTTGTCTGAAATTGTA GCAGCAGGAATTGATCCTTTAAGCCTTGTAACAAGTTCAAATTATTCTGAAGGTAAGAAT ACTAAGGTTTCCGGTGTGTTGCCATGGGATGTTTCAAATAATGTTTACTATGTAAATGTT GATTTGACAGGAGAAAATATCTACCCAGGCGGTCAGTCTGCGTGCAGACGAGAAGTTCAG TTCAGAATTGCCGCACCACAGGGAACAACATATTGGAATCCGAAAAATGATTTCTCATAT GATGGATTACCAACCACCAGTACTGTAAATACGGTTACCAACATACCTGTTTATGATAAC GGCGTAAAAGTATTTGGTAACGAACCCGCAGGTGGATCGGAAAACCCTGATCCTGAAATC TTGTATGGAGACGTAAACAGCGACAAAAATGTAGATGCATTGGACTTTGCTGCATTGAAG AAATATTTACTTGGAGGCACTTCCAGCATAGATGTTAAGGCTGCAGATACATACAAGGAT GGGAATATTGACGCTATAGATATGGCTACCTTGAAGAAGTATTTATTGGGAACAATCACC CAATTACCTCAAGGCTAA
- Chromosome Location
- Not Available
- Locus
- Not Available
- External Identifiers
Resource Link UniProtKB ID P37700 UniProtKB Entry Name GUNG_CLOCE GenBank Protein ID 551774 GenBank Gene ID M87018 - General References
- Bagnara-Tardif C, Gaudin C, Belaich A, Hoest P, Citard T, Belaich JP: Sequence analysis of a gene cluster encoding cellulases from Clostridium cellulolyticum. Gene. 1992 Sep 21;119(1):17-28. [Article]
Drug Relations
- Drug Relations
DrugBank ID Name Drug group Pharmacological action? Actions Details DB02061 Cellobiose experimental unknown Details DB02361 S-Methyl Thiocysteine Group experimental unknown Details DB03584 4-Thio-beta-D-glucopyranose experimental unknown Details DB03859 1-thio-beta-D-glucopyranose experimental unknown Details DB02379 Beta-D-Glucose experimental unknown Details