Urease subunit gamma

Details

Name
Urease subunit gamma
Synonyms
  • 3.5.1.5
  • Urea amidohydrolase subunit gamma
Gene Name
ureA
Organism
Sporosarcina pasteurii
Amino acid sequence
>lcl|BSEQ0012796|Urease subunit gamma
MHLNPAEKEKLQIFLASELLLRRKARGLKLNYPEAVAIITSFIMEGARDGKTVAMLMEEG
KHVLTRDDVMEGVPEMIDDIQAEATFPDGTKLVTVHNPIS
Number of residues
100
Molecular Weight
11145.885
Theoretical pI
5.16
GO Classification
Functions
nickel cation binding / urease activity
Processes
urea catabolic process
Components
cytoplasm
General Function
Urease activity
Specific Function
Not Available
Pfam Domain Function
Transmembrane Regions
Not Available
Cellular Location
Cytoplasm
Gene sequence
>lcl|BSEQ0007666|303 bp
ATGCATTTAAATCCAGCAGAGAAAGAAAAATTACAAATTTTTCTAGCGAGCGAATTACTC
TTAAGGCGTAAAGCAAGAGGTCTTAAGTTGAACTATCCGGAAGCAGTTGCGATCATCACA
AGTTTCATTATGGAGGGTGCGCGTGACGGAAAGACGGTAGCGATGCTAATGGAAGAAGGA
AAACACGTTCTTACGAGGGACGATGTTATGGAAGGTGTACCAGAAATGATTGATGATATT
CAAGCAGAAGCTACTTTCCCGGATGGAACTAAACTCGTAACTGTTCACAATCCAATTTCT
TAA
Chromosome Location
Not Available
Locus
Not Available
External Identifiers
ResourceLink
UniProtKB IDP41022
UniProtKB Entry NameURE3_SPOPA
GenBank Protein ID498709
GenBank Gene IDX78411
General References
  1. Benini S, Ciurli S, Rypniewski WR, Wilson KS, Mangani S: Crystallization and preliminary high-resolution X-ray diffraction analysis of native and beta-mercaptoethanol-inhibited urease from Bacillus pasteurii. Acta Crystallogr D Biol Crystallogr. 1998 May 1;54(Pt 3):409-12. [Article]
  2. Benini S, Rypniewski WR, Wilson KS, Miletti S, Ciurli S, Mangani S: A new proposal for urease mechanism based on the crystal structures of the native and inhibited enzyme from Bacillus pasteurii: why urea hydrolysis costs two nickels. Structure. 1999 Feb 15;7(2):205-16. [Article]
  3. Benini S, Rypniewski WR, Wilson KS, Miletti S, Ciurli S, Mangani S: The complex of Bacillus pasteurii urease with acetohydroxamate anion from X-ray data at 1.55 A resolution. J Biol Inorg Chem. 2000 Feb;5(1):110-8. [Article]
  4. Benini S, Rypniewski WR, Wilson KS, Ciurli S, Mangani S: Structure-based rationalization of urease inhibition by phosphate: novel insights into the enzyme mechanism. J Biol Inorg Chem. 2001 Oct;6(8):778-90. [Article]
  5. Benini S, Rypniewski WR, Wilson KS, Mangani S, Ciurli S: Molecular details of urease inhibition by boric acid: insights into the catalytic mechanism. J Am Chem Soc. 2004 Mar 31;126(12):3714-5. [Article]

Drug Relations

Drug Relations
DrugBank IDNameDrug groupPharmacological action?ActionsDetails
DB02899N-CarboxymethionineexperimentalunknownDetails