Afamin

Details

Name
Afamin
Synonyms
  • ALB2
  • ALBA
  • Alpha-Alb
  • Alpha-albumin
Gene Name
AFM
Organism
Humans
Amino acid sequence
>lcl|BSEQ0049673|Afamin
MKLLKLTGFIFFLFFLTESLTLPTQPRDIENFNSTQKFIEDNIEYITIIAFAQYVQEATF
EEMEKLVKDMVEYKDRCMADKTLPECSKLPNNVLQEKICAMEGLPQKHNFSHCCSKVDAQ
RRLCFFYNKKSDVGFLPPFPTLDPEEKCQAYESNRESLLNHFLYEVARRNPFVFAPTLLT
VAVHFEEVAKSCCEEQNKVNCLQTRAIPVTQYLKAFSSYQKHVCGALLKFGTKVVHFIYI
AILSQKFPKIEFKELISLVEDVSSNYDGCCEGDVVQCIRDTSKVMNHICSKQDSISSKIK
ECCEKKIPERGQCIINSNKDDRPKDLSLREGKFTDSENVCQERDADPDTFFAKFTFEYSR
RHPDLSIPELLRIVQIYKDLLRNCCNTENPPGCYRYAEDKFNETTEKSLKMVQQECKHFQ
NLGKDGLKYHYLIRLTKIAPQLSTEELVSLGEKMVTAFTTCCTLSEEFACVDNLADLVFG
ELCGVNENRTINPAVDHCCKTNFAFRRPCFESLKADKTYVPPPFSQDLFTFHADMCQSQN
EELQRKTDRFLVNLVKLKHELTDEELQSLFTNFANVVDKCCKAESPEVCFNEESPKIGN
Number of residues
599
Molecular Weight
69068.47
Theoretical pI
Not Available
GO Classification
Functions
vitamin E binding
Processes
vitamin transport
Components
blood microparticle / extracellular exosome / extracellular region / extracellular space
General Function
Vitamin E binding protein. May transport vitamin E in body fluids under conditions where the lipoprotein system is not sufficient. May be involved in the regulation and transport of vitamin E at the blood-brain barrier.
Specific Function
Vitamin e binding
Pfam Domain Function
Transmembrane Regions
Not Available
Cellular Location
Secreted
Gene sequence
>lcl|BSEQ0049674|Afamin (AFM)
ATGAAACTACTAAAACTTACAGGTTTTATTTTTTTCTTGTTTTTTTTGACTGAATCCCTA
ACCCTGCCCACACAACCTCGGGATATAGAGAACTTCAATAGTACTCAAAAATTTATAGAA
GATAATATTGAATACATCACCATCATTGCATTTGCTCAGTATGTTCAGGAAGCAACCTTT
GAAGAAATGGAAAAGCTGGTGAAAGACATGGTAGAATACAAAGACAGATGTATGGCTGAC
AAGACGCTCCCAGAGTGTTCAAAATTACCTAATAATGTTTTACAGGAAAAAATATGTGCT
ATGGAGGGGCTGCCACAAAAGCATAATTTCTCACACTGCTGCAGTAAGGTTGATGCTCAA
AGAAGACTCTGTTTCTTCTATAACAAGAAATCTGATGTGGGATTTCTGCCTCCTTTCCCT
ACCCTGGATCCCGAAGAGAAATGCCAGGCTTATGAAAGTAACAGAGAATCCCTTTTAAAT
CACTTTTTATATGAAGTTGCCAGAAGGAACCCATTTGTCTTCGCCCCTACACTTCTAACT
GTTGCTGTTCATTTTGAGGAGGTGGCCAAATCATGTTGTGAAGAACAAAACAAAGTCAAC
TGCCTTCAAACAAGGGCAATACCTGTCACACAATATTTAAAAGCATTTTCTTCTTATCAA
AAACATGTCTGTGGGGCACTTTTGAAATTTGGAACCAAAGTTGTACACTTTATATATATT
GCGATACTCAGTCAAAAATTCCCCAAGATTGAATTTAAGGAGCTTATTTCTCTTGTAGAA
GATGTTTCTTCCAACTATGATGGATGCTGTGAAGGGGATGTTGTGCAGTGCATCCGTGAC
ACGAGCAAGGTTATGAACCATATTTGTTCAAAACAAGATTCTATCTCCAGCAAAATCAAA
GAGTGCTGTGAAAAGAAAATACCAGAGCGCGGCCAGTGCATAATTAACTCAAACAAAGAT
GATAGACCAAAGGATTTATCTCTAAGAGAAGGAAAATTTACTGACAGTGAAAATGTGTGT
CAAGAACGAGATGCTGACCCAGACACCTTCTTTGCGAAGTTTACTTTTGAATACTCAAGG
AGACATCCAGACCTGTCTATACCAGAGCTTTTAAGAATTGTTCAAATATACAAAGATCTC
CTGAGAAATTGCTGCAACACAGAAAACCCTCCAGGTTGTTACCGTTACGCGGAAGACAAA
TTCAATGAGACAACTGAGAAAAGCCTCAAGATGGTACAACAAGAATGTAAACATTTCCAG
AATTTGGGGAAGGATGGTTTGAAATACCATTACCTCATCAGGCTCACGAAGATAGCTCCC
CAACTCTCCACTGAAGAACTGGTGTCTCTTGGCGAGAAAATGGTGACAGCTTTCACTACT
TGCTGTACGCTAAGTGAAGAGTTTGCCTGTGTTGATAATTTGGCAGATTTAGTTTTTGGA
GAGTTATGTGGAGTAAATGAAAATCGAACTATCAACCCTGCTGTGGACCACTGCTGTAAA
ACAAACTTTGCCTTCAGAAGGCCCTGCTTTGAGAGTTTGAAAGCTGATAAAACATATGTG
CCTCCACCTTTCTCTCAAGATTTATTTACCTTTCACGCAGACATGTGTCAATCTCAGAAT
GAGGAGCTTCAGAGGAAGACAGACAGGTTTCTTGTCAACTTAGTGAAGCTGAAGCATGAA
CTCACAGATGAAGAGCTGCAGTCTTTGTTTACAAATTTCGCAAATGTAGTGGATAAGTGC
TGCAAAGCAGAGAGTCCTGAAGTCTGCTTTAATGAAGAGAGTCCAAAAATTGGCAACTGA
Chromosome Location
4
Locus
4q13.3
External Identifiers
ResourceLink
UniProtKB IDP43652
UniProtKB Entry NameAFAM_HUMAN
HGNC IDHGNC:316
General References
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Drug Relations

Drug Relations
DrugBank IDNameDrug groupPharmacological action?ActionsDetails
DB09130Copperapproved, investigationalunknownDetails