Ribose-5-phosphate isomerase A

Details

Name

Ribose-5-phosphate isomerase A

Synonyms

• 5.3.1.6
• Phosphoriboisomerase A
• PRI

Gene Name

rpiA

Organism

Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)

Amino acid sequence

>lcl|BSEQ0017045|Ribose-5-phosphate isomerase A
MNQLEMKKLAAQAALQYVKADTIVGVGSGSTVNCFIEALGTIKDKIQGAVAASKESEELL
RKQGIEVFNANDVSSLDIYVDGADEINPQKMMIKGGGAALTREKIVAALAKKFICIVDSS
KQVDVLGSTFPLPVEVIPMARSQVGRKLAALGGSPEYREGVVTDNGNVILDVHNFSILNP
VEIEKELNNVAGVVTNGIFALRGADVVIVGTPEGAKVID

Number of residues

219

Molecular Weight

23093.47

Theoretical pI

4.78

GO Classification

Functions

ribose-5-phosphate isomerase activity

Processes

pentose-phosphate shunt, non-oxidative branch

General Function

Ribose-5-phosphate isomerase activity

Specific Function

Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.

Pfam Domain Function

• Rib_5-P_isom_A (PF06026)

Transmembrane Regions

Not Available

Cellular Location

Not Available

Gene sequence

>lcl|BSEQ0017046|Ribose-5-phosphate isomerase A (rpiA)
ATGAATCAATTAGAAATGAAAAAACTCGCCGCACAAGCTGCATTACAATATGTAAAAGCA
GATACGATTGTTGGGGTGGGAAGTGGCTCCACAGTGAACTGCTTTATTGAAGCTTTAGGT
ACAATCAAAGATAAAATTCAAGGTGCCGTTGCGGCTTCAAAAGAATCAGAAGAATTATTA
CGTAAGCAAGGTATCGAAGTATTTAATGCAAATGATGTCTCTAGCTTAGATATTTATGTG
GATGGTGCGGATGAAATCAATCCACAAAAAATGATGATTAAAGGCGGCGGCGCAGCACTC
ACTCGTGAAAAAATAGTCGCTGCATTAGCGAAAAAATTTATTTGTATTGTGGATTCAAGT
AAGCAAGTGGATGTGTTGGGTTCAACTTTCCCATTACCAGTTGAAGTGATTCCTATGGCA
CGCTCACAAGTAGGCAGAAAATTAGCCGCACTTGGTGGCTCACCTGAATATCGTGAAGGG
GTGGTGACTGACAACGGCAATGTGATTTTAGATGTACACAACTTCAGTATTTTAAATCCA
GTCGAAATTGAAAAAGAATTAAACAACGTTGCAGGTGTCGTCACTAATGGGATATTCGCG
TTACGTGGTGCAGATGTTGTGATCGTCGGGACGCCTGAGGGTGCCAAAGTTATTGACTAA

Chromosome Location

Not Available

Locus

Not Available

External Identifiers

Resource	Link
UniProtKB ID	P44725
UniProtKB Entry Name	RPIA_HAEIN
GenBank Gene ID	L42023

General References

1. Fleischmann RD, Adams MD, White O, Clayton RA, Kirkness EF, Kerlavage AR, Bult CJ, Tomb JF, Dougherty BA, Merrick JM, et al.: Whole-genome random sequencing and assembly of Haemophilus influenzae Rd. Science. 1995 Jul 28;269(5223):496-512. [Article]
2. Langen H, Takacs B, Evers S, Berndt P, Lahm HW, Wipf B, Gray C, Fountoulakis M: Two-dimensional map of the proteome of Haemophilus influenzae. Electrophoresis. 2000 Jan;21(2):411-29. [Article]

Drug Relations

Drug Relations

DrugBank ID	Name	Drug group	Pharmacological action?	Actions	Details
DB04272	Citric acid	approved, nutraceutical, vet_approved	unknown		Details