ADP compounds hydrolase NudE
Details
- Name
- ADP compounds hydrolase NudE
- Synonyms
- 3.6.1.-
- yrfE
- Gene Name
- nudE
- Organism
- Escherichia coli (strain K12)
- Amino acid sequence
>lcl|BSEQ0016868|ADP compounds hydrolase NudE MSKSLQKPTILNVETVARSRLFTVESVDLEFSNGVRRVYERMRPTNREAVMIVPIVDDHL ILIREYAVGTESYELGFSKGLIDPGESVYEAANRELKEEVGFGANDLTFLKKLSMAPSYF SSKMNIVVAQDLYPESLEGDEPEPLPQVRWPLAHMMDLLEDPDFNEARNVSALFLVREWL KGQGRV
- Number of residues
- 186
- Molecular Weight
- 21152.975
- Theoretical pI
- 4.56
- GO Classification
- FunctionsADP-sugar diphosphatase activity / magnesium ion bindingComponentscytosol
- General Function
- Magnesium ion binding
- Specific Function
- Active on adenosine(5')triphospho(5')adenosine (Ap3A), ADP-ribose, NADH, adenosine(5')diphospho(5')adenosine (Ap2A).
- Pfam Domain Function
- NUDIX (PF00293)
- Transmembrane Regions
- Not Available
- Cellular Location
- Not Available
- Gene sequence
>lcl|BSEQ0016869|ADP compounds hydrolase NudE (nudE) ATGAGCAAATCATTACAAAAACCCACCATTCTGAATGTTGAAACTGTAGCCCGTTCCCGA CTGTTTACCGTCGAGAGCGTGGATCTGGAGTTCAGCAATGGCGTGCGGCGTGTTTATGAA CGAATGCGTCCAACCAACCGGGAAGCAGTGATGATTGTGCCGATTGTGGACGATCACCTG ATCCTGATCCGCGAATACGCAGTGGGAACTGAATCCTACGAATTAGGTTTTTCGAAAGGA TTAATTGATCCGGGTGAAAGCGTCTACGAAGCCGCTAACCGCGAGCTAAAAGAAGAGGTT GGATTTGGAGCGAACGATCTGACTTTTTTGAAGAAGCTCAGCATGGCACCGTCTTACTTT TCCAGCAAAATGAATATCGTGGTAGCGCAAGATCTCTACCCGGAATCACTGGAAGGCGAT GAGCCAGAGCCGCTACCACAGGTGCGCTGGCCGCTGGCGCATATGATGGATTTGCTGGAA GACCCTGACTTCAATGAAGCGCGCAATGTCAGTGCGCTGTTCCTCGTGCGCGAATGGTTG AAAGGGCAGGGGCGAGTGTAA
- Chromosome Location
- Not Available
- Locus
- Not Available
- External Identifiers
Resource Link UniProtKB ID P45799 UniProtKB Entry Name NUDE_ECOLI GenBank Gene ID U18997 - General References
- Blattner FR, Plunkett G 3rd, Bloch CA, Perna NT, Burland V, Riley M, Collado-Vides J, Glasner JD, Rode CK, Mayhew GF, Gregor J, Davis NW, Kirkpatrick HA, Goeden MA, Rose DJ, Mau B, Shao Y: The complete genome sequence of Escherichia coli K-12. Science. 1997 Sep 5;277(5331):1453-62. [Article]
- Hayashi K, Morooka N, Yamamoto Y, Fujita K, Isono K, Choi S, Ohtsubo E, Baba T, Wanner BL, Mori H, Horiuchi T: Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110. Mol Syst Biol. 2006;2:2006.0007. Epub 2006 Feb 21. [Article]
- O'Handley SF, Frick DN, Dunn CA, Bessman MJ: Orf186 represents a new member of the Nudix hydrolases, active on adenosine(5')triphospho(5')adenosine, ADP-ribose, and NADH. J Biol Chem. 1998 Feb 6;273(6):3192-7. [Article]
- Badger J, Sauder JM, Adams JM, Antonysamy S, Bain K, Bergseid MG, Buchanan SG, Buchanan MD, Batiyenko Y, Christopher JA, Emtage S, Eroshkina A, Feil I, Furlong EB, Gajiwala KS, Gao X, He D, Hendle J, Huber A, Hoda K, Kearins P, Kissinger C, Laubert B, Lewis HA, Lin J, Loomis K, Lorimer D, Louie G, Maletic M, Marsh CD, Miller I, Molinari J, Muller-Dieckmann HJ, Newman JM, Noland BW, Pagarigan B, Park F, Peat TS, Post KW, Radojicic S, Ramos A, Romero R, Rutter ME, Sanderson WE, Schwinn KD, Tresser J, Winhoven J, Wright TA, Wu L, Xu J, Harris TJ: Structural analysis of a set of proteins resulting from a bacterial genomics project. Proteins. 2005 Sep 1;60(4):787-96. [Article]