Heat shock 70 kDa protein 13
Details
- Name
- Heat shock 70 kDa protein 13
- Synonyms
- Microsomal stress-70 protein ATPase core
- STCH
- Stress-70 protein chaperone microsome-associated 60 kDa protein
- Gene Name
- HSPA13
- Organism
- Humans
- Amino acid sequence
>lcl|BSEQ0049630|Heat shock 70 kDa protein 13 MAREMTILGSAVLTLLLAGYLAQQYLPLPTPKVIGIDLGTTYCSVGVFFPGTGKVKVIPD ENGHISIPSMVSFTDNDVYVGYESVELADSNPQNTIYDAKRFIGKIFTAEELEAEIGRYP FKVLNKNGMVEFSVTSNETITVSPEYVGSRLLLKLKEMAEAYLGMPVANAVISVPAEFDL KQRNSTIEAANLAGLKILRVINEPTAAAMAYGLHKADVFHVLVIDLGGGTLDVSLLNKQG GMFLTRAMSGNNKLGGQDFNQRLLQYLYKQIYQTYGFVPSRKEEIHRLRQAVEMVKLNLT LHQSAQLSVLLTVEEQDRKEPHSSDTELPKDKLSSADDHRVNSGFGRGLSDKKSGESQVL FETEISRKLFDTLNEDLFQKILVPIQQVLKEGHLEKTEIDEVVLVGGSTRIPRIRQVIQE FFGKDPNTSVDPDLAVVTGVAIQAGIDGGSWPLQVSALEIPNKHLQKTNFN
- Number of residues
- 471
- Molecular Weight
- 51927.08
- Theoretical pI
- Not Available
- GO Classification
- FunctionsATP bindingComponentsendoplasmic reticulum / extracellular exosome / intracellular membrane-bounded organelle
- General Function
- Has peptide-independent ATPase activity.
- Specific Function
- Atp binding
- Pfam Domain Function
- HSP70 (PF00012)
- Transmembrane Regions
- Not Available
- Cellular Location
- Microsome
- Gene sequence
>lcl|BSEQ0049631|Heat shock 70 kDa protein 13 (HSPA13) ATGGCCAGAGAGATGACGATCTTAGGATCGGCTGTTTTGACTCTCCTGTTGGCCGGCTAT TTGGCACAACAGTATTTACCATTGCCTACTCCTAAAGTGATTGGTATTGATCTTGGCACC ACCTATTGTTCTGTTGGGGTGTTTTTTCCTGGCACAGGAAAAGTAAAGGTGATTCCAGAT GAAAATGGGCATATCAGCATACCCAGCATGGTGTCTTTTACTGACAATGATGTATATGTG GGATATGAAAGCGTAGAGCTGGCAGATTCAAATCCTCAAAACACAATATATGATGCCAAA AGATTCATAGGCAAGATTTTTACCGCAGAAGAGTTGGAGGCTGAAATTGGCAGATACCCA TTTAAGGTTTTAAACAAAAATGGAATGGTTGAGTTTTCTGTGACAAGTAATGAGACCATC ACAGTGTCCCCAGAATATGTTGGCTCTCGACTATTGTTGAAGTTAAAGGAAATGGCAGAG GCATATCTTGGAATGCCAGTTGCCAATGCTGTCATTTCTGTACCAGCAGAATTTGATCTA AAACAGAGAAATTCAACAATTGAAGCTGCTAACCTTGCAGGACTGAAGATTTTGAGGGTA ATAAATGAACCCACAGCAGCAGCTATGGCCTATGGTCTCCACAAGGCTGACGTCTTCCAC GTCTTGGTGATAGACTTGGGCGGAGGAACTCTAGATGTGTCTTTACTGAATAAACAAGGA GGGATGTTTCTAACCCGAGCAATGTCTGGAAACAATAAACTTGGAGGACAGGACTTCAAT CAGAGATTGCTTCAGTACTTATATAAACAGATCTATCAAACATATGGCTTCGTGCCCTCT AGGAAAGAGGAAATCCACAGATTGAGACAAGCTGTGGAAATGGTCAAATTAAATCTGACT CTTCATCAATCTGCTCAGTTGTCAGTATTACTAACGGTGGAGGAGCAGGACAGGAAGGAA CCTCACAGTAGTGACACTGAACTGCCAAAAGACAAACTTTCCTCAGCAGATGACCATCGC GTGAACAGTGGGTTTGGACGTGGCCTTTCTGATAAGAAAAGTGGAGAAAGTCAGGTTTTA TTTGAAACAGAAATATCACGGAAACTCTTTGATACCCTTAATGAAGACCTCTTTCAGAAA ATACTGGTACCCATTCAGCAAGTATTGAAAGAAGGCCACCTGGAAAAGACTGAGATTGAT GAGGTGGTTTTAGTTGGGGGCTCCACTCGTATTCCTCGGATCCGTCAAGTCATTCAAGAG TTCTTTGGAAAAGATCCCAACACATCTGTAGACCCTGACCTAGCAGTAGTAACGGGAGTG GCTATCCAAGCAGGGATTGATGGAGGCTCTTGGCCTCTCCAAGTCAGTGCTTTAGAAATT CCCAATAAGCATTTACAAAAAACCAACTTCAACTGA
- Chromosome Location
- 21
- Locus
- 21q11.2
- External Identifiers
Resource Link UniProtKB ID P48723 UniProtKB Entry Name HSP13_HUMAN HGNC ID HGNC:11375 - General References
- Otterson GA, Flynn GC, Kratzke RA, Coxon A, Johnston PG, Kaye FJ: Stch encodes the 'ATPase core' of a microsomal stress 70 protein. EMBO J. 1994 Mar 1;13(5):1216-25. [Article]
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- Kaye FJ, Modi S, Ivanovska I, Koonin EV, Thress K, Kubo A, Kornbluth S, Rose MD: A family of ubiquitin-like proteins binds the ATPase domain of Hsp70-like Stch. FEBS Lett. 2000 Feb 11;467(2-3):348-55. [Article]
- Burkard TR, Planyavsky M, Kaupe I, Breitwieser FP, Burckstummer T, Bennett KL, Superti-Furga G, Colinge J: Initial characterization of the human central proteome. BMC Syst Biol. 2011 Jan 26;5:17. doi: 10.1186/1752-0509-5-17. [Article]