Destrin
Details
- Name
- Destrin
- Synonyms
- ACTDP
- Actin-depolymerizing factor
- ADF
- DSN
- Gene Name
- DSTN
- Organism
- Humans
- Amino acid sequence
>lcl|BSEQ0007926|Destrin MASGVQVADEVCRIFYDMKVRKCSTPEEIKKRKKAVIFCLSADKKCIIVEEGKEILVGDV GVTITDPFKHFVGMLPEKDCRYALYDASFETKESRKEELMFFLWAPELAPLKSKMIYASS KDAIKKKFQGIKHECQANGPEDLNRACIAEKLGGSLIVAFEGCPV
- Number of residues
- 165
- Molecular Weight
- 18505.54
- Theoretical pI
- 7.97
- GO Classification
- Processesactin filament depolymerization / actin filament severing / actin polymerization or depolymerization / positive regulation of actin filament depolymerizationComponentsactin cytoskeleton / cortical actin cytoskeleton / extracellular exosome
- General Function
- Not Available
- Specific Function
- Actin-depolymerizing protein. Severs actin filaments (F-actin) and binds to actin monomers (G-actin). Acts in a pH-independent manner.
- Pfam Domain Function
- Cofilin_ADF (PF00241)
- Transmembrane Regions
- Not Available
- Cellular Location
- Not Available
- Gene sequence
>lcl|BSEQ0021694|Destrin (DSTN) ATGAAAGTTCGTAAATGCTCCACACCAGAAGAAATCAAGAAAAGAAAGAAGGCTGTCATT TTTTGTCTCAGTGCAGACAAAAAGTGCATCATTGTAGAAGAAGGCAAAGAGATCTTGGTT GGAGATGTTGGTGTAACCATAACTGATCCTTTCAAGCATTTTGTGGGAATGCTTCCTGAA AAAGATTGTCGCTATGCTTTGTATGATGCAAGCTTTGAAACAAAAGAATCCAGAAAAGAA GAGTTGATGTTTTTTTTGTGGGCACCAGAACTAGCACCTCTGAAAAGTAAAATGATCTAT GCAAGCTCCAAGGATGCAATTAAAAAGAAATTTCAAGGCATAAAACATGAATGTCAAGCA AATGGACCAGAAGATCTCAATCGGGCTTGTATTGCTGAAAAGTTAGGTGGATCCTTAATT GTAGCCTTTGAAGGATGCCCTGTGTAG
- Chromosome Location
- 20
- Locus
- 20p12.1
- External Identifiers
Resource Link UniProtKB ID P60981 UniProtKB Entry Name DEST_HUMAN GenBank Protein ID 415587 GenBank Gene ID S65738 HGNC ID HGNC:15750 - General References
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