Glucose-1-phosphate thymidylyltransferase 2
Details
- Name
- Glucose-1-phosphate thymidylyltransferase 2
- Synonyms
- 2.7.7.24
- dTDP-glucose pyrophosphorylase 2
- dTDP-glucose synthase 2
- rmlA2
- Gene Name
- rffH
- Organism
- Shigella flexneri
- Amino acid sequence
>lcl|BSEQ0011372|Glucose-1-phosphate thymidylyltransferase 2 MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTV EKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKTGYGQYLLELLRARPRQY
- Number of residues
- 293
- Molecular Weight
- 32734.13
- Theoretical pI
- 5.08
- GO Classification
- Functionsglucose-1-phosphate thymidylyltransferase activity / metal ion bindingProcessesenterobacterial common antigen biosynthetic process / extracellular polysaccharide biosynthetic process
- General Function
- Metal ion binding
- Specific Function
- Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.
- Pfam Domain Function
- NTP_transferase (PF00483)
- Transmembrane Regions
- Not Available
- Cellular Location
- Not Available
- Gene sequence
>lcl|BSEQ0011373|Glucose-1-phosphate thymidylyltransferase 2 (rffH) ATGAAGGGTATTATCCTGGCGGGCGGTTCCGGTACCCGATTGCATCCGATTACGCGCGGC GTATCGAAGCAACTGTTGCCGATTTACGATAAGCCAATGATTTACTATCCGCTGTCGGTG CTGATGCTGGCCGGTATCCGCGAAATTCTCATCATCACTACGCCGGAAGATAAAGGTTAT TTCCAGCGCCTGCTGGGCGATGGTAGTGAGTTCGGTATCCAGCTGGAATATGCCGAACAG CCCAGCCCGGACGGTCTGGCGCAGGCCTTTATCATCGGTGAAACCTTCCTTAATGGTGAA CCTTCTTGTCTGGTGCTGGGCGATAACATCTTCTTCGGTCAGGGCTTCAGTCCGAAGCTG CGTCATGTTGCGGCGCGCACGGAAGGGGCGACGGTTTTTGGCTATCAGGTGATGGACCCG GAACGCTTTGGCGTGGTGGAATTTGACGACAATTTCCGCGCTATCTCGCTTGAAGAAAAG CCAAAACAGCCGAAGTCAAACTGGGCGGTGACCGGGCTTTATTTCTACGACAGTAAAGTC GTGGAGTACGCAAAGCAGGTGAAGCCGTCGGAGCGCGGTGAACTGGAGATTACCTCCATC AACCAGATGTACCTCGAGGCGGGCAACCTGACCGTTGAACTGCTCGGGCGCGGATTTGCC TGGCTGGATACCGGCACTCACGACAGCCTGATTGAGGCCAGCACTTTTGTGCAGACAGTA GAAAAACGCCAGGGCTTTAAGATTGCCTGCCTGGAAGAGATCGCCTGGCGTAACGGCTGG CTCGATGACGAGGGTGTGAAGCGTGCTGCCAGTTCATTAGCGAAAACTGGCTACGGCCAA TATCTGCTGGAGTTACTTCGTGCCCGTCCGCGCCAGTATTGA
- Chromosome Location
- Not Available
- Locus
- Not Available
- External Identifiers
Resource Link UniProtKB ID P61888 UniProtKB Entry Name RMLA2_SHIFL GenBank Protein ID 24054349 GenBank Gene ID AE005674 - General References
- Jin Q, Yuan Z, Xu J, Wang Y, Shen Y, Lu W, Wang J, Liu H, Yang J, Yang F, Zhang X, Zhang J, Yang G, Wu H, Qu D, Dong J, Sun L, Xue Y, Zhao A, Gao Y, Zhu J, Kan B, Ding K, Chen S, Cheng H, Yao Z, He B, Chen R, Ma D, Qiang B, Wen Y, Hou Y, Yu J: Genome sequence of Shigella flexneri 2a: insights into pathogenicity through comparison with genomes of Escherichia coli K12 and O157. Nucleic Acids Res. 2002 Oct 15;30(20):4432-41. [Article]
- Wei J, Goldberg MB, Burland V, Venkatesan MM, Deng W, Fournier G, Mayhew GF, Plunkett G 3rd, Rose DJ, Darling A, Mau B, Perna NT, Payne SM, Runyen-Janecky LJ, Zhou S, Schwartz DC, Blattner FR: Complete genome sequence and comparative genomics of Shigella flexneri serotype 2a strain 2457T. Infect Immun. 2003 May;71(5):2775-86. [Article]