1-cys peroxiredoxin
Details
- Name
- 1-cys peroxiredoxin
- Synonyms
- Peroxiredoxin
- PfAOP
- Gene Name
- prx
- Organism
- Plasmodium falciparum (isolate 3D7)
- Amino acid sequence
>lcl|BSEQ0022319|1-cys peroxiredoxin MRMRRTILIFTVILIPLTFCFKNALIKHSINIVSKRGNSKNRFSQKVYESKNIDLENDIK ENDLIPNVKVMIDVRNMNNISDTDGSPNDFTSIDTHELFNNKKILLISLPGAFTPTCSTK MIPGYEEEYDYFIKENNFDDIYCITNNDIYVLKSWFKSMDIKKIKYISDGNSSFTESMNM LVDKSNFFMGMRPWRFVAIVENNILVKMFQEKDKQHNIQTDPYDISTVNNVKEFLKNNQL
- Number of residues
- 240
- Molecular Weight
- 28124.115
- Theoretical pI
- 8.03
- GO Classification
- Functionsantioxidant activity / oxidoreductase activityComponentsapicoplast
- General Function
- Oxidoreductase activity
- Specific Function
- Not Available
- Pfam Domain Function
- Redoxin (PF08534)
- Transmembrane Regions
- Not Available
- Cellular Location
- Not Available
- Gene sequence
>lcl|BSEQ0022320|1-cys peroxiredoxin (prx) ATGAGAATGAGAAGAACAATACTAATATTTACTGTTATATTAATACCTCTTACTTTTTGT TTTAAAAATGCTTTAATTAAGCATTCTATTAATATAGTATCCAAGCGAGGAAACTCGAAG AATCGGTTTTCCCAAAAAGTTTATGAATCCAAAAATATAGATTTGGAAAATGATATAAAA GAAAATGATCTTATTCCTAACGTGAAAGTTATGATTGACGTAAGAAATATGAACAACATA TCTGATACCGATGGGAGCCCAAACGATTTTACTTCAATAGATACACATGAATTATTTAAT AACAAAAAGATTTTATTAATCAGTTTACCTGGGGCATTTACGCCTACTTGCAGTACAAAA ATGATACCAGGATATGAAGAAGAATATGATTATTTTATAAAAGAGAATAATTTTGATGAC ATTTATTGTATTACTAATAATGATATATATGTATTAAAGAGTTGGTTTAAAAGTATGGAT ATAAAAAAAATAAAATATATAAGTGATGGTAATAGTTCATTTACAGAAAGTATGAATATG TTAGTAGACAAATCTAATTTTTTTATGGGAATGAGACCTTGGAGATTTGTTGCTATTGTT GAAAATAATATTTTGGTTAAAATGTTTCAAGAAAAAGATAAACAACATAATATTCAAACA GACCCATATGATATATCAACTGTCAATAATGTAAAAGAGTTTTTAAAAAATAATCAGTTA TAA
- Chromosome Location
- Not Available
- Locus
- Not Available
- External Identifiers
Resource Link UniProtKB ID Q5MYR6 UniProtKB Entry Name Q5MYR6_PLAF7 GenBank Gene ID AY306209 - General References
- Gardner MJ, Hall N, Fung E, White O, Berriman M, Hyman RW, Carlton JM, Pain A, Nelson KE, Bowman S, Paulsen IT, James K, Eisen JA, Rutherford K, Salzberg SL, Craig A, Kyes S, Chan MS, Nene V, Shallom SJ, Suh B, Peterson J, Angiuoli S, Pertea M, Allen J, Selengut J, Haft D, Mather MW, Vaidya AB, Martin DM, Fairlamb AH, Fraunholz MJ, Roos DS, Ralph SA, McFadden GI, Cummings LM, Subramanian GM, Mungall C, Venter JC, Carucci DJ, Hoffman SL, Newbold C, Davis RW, Fraser CM, Barrell B: Genome sequence of the human malaria parasite Plasmodium falciparum. Nature. 2002 Oct 3;419(6906):498-511. [Article]
- Hall N, Pain A, Berriman M, Churcher C, Harris B, Harris D, Mungall K, Bowman S, Atkin R, Baker S, Barron A, Brooks K, Buckee CO, Burrows C, Cherevach I, Chillingworth C, Chillingworth T, Christodoulou Z, Clark L, Clark R, Corton C, Cronin A, Davies R, Davis P, Dear P, Dearden F, Doggett J, Feltwell T, Goble A, Goodhead I, Gwilliam R, Hamlin N, Hance Z, Harper D, Hauser H, Hornsby T, Holroyd S, Horrocks P, Humphray S, Jagels K, James KD, Johnson D, Kerhornou A, Knights A, Konfortov B, Kyes S, Larke N, Lawson D, Lennard N, Line A, Maddison M, McLean J, Mooney P, Moule S, Murphy L, Oliver K, Ormond D, Price C, Quail MA, Rabbinowitsch E, Rajandream MA, Rutter S, Rutherford KM, Sanders M, Simmonds M, Seeger K, Sharp S, Smith R, Squares R, Squares S, Stevens K, Taylor K, Tivey A, Unwin L, Whitehead S, Woodward J, Sulston JE, Craig A, Newbold C, Barrell BG: Sequence of Plasmodium falciparum chromosomes 1, 3-9 and 13. Nature. 2002 Oct 3;419(6906):527-31. [Article]
- Sarma GN, Nickel C, Rahlfs S, Fischer M, Becker K, Karplus PA: Crystal structure of a novel Plasmodium falciparum 1-Cys peroxiredoxin. J Mol Biol. 2005 Mar 4;346(4):1021-34. Epub 2005 Jan 8. [Article]
- Staudacher V, Djuika CF, Koduka J, Schlossarek S, Kopp J, Buchler M, Lanzer M, Deponte M: Plasmodium falciparum antioxidant protein reveals a novel mechanism for balancing turnover and inactivation of peroxiredoxins. Free Radic Biol Med. 2015 Aug;85:228-36. doi: 10.1016/j.freeradbiomed.2015.04.030. Epub 2015 May 5. [Article]