Chorismate mutase AroH

Details

Name
Chorismate mutase AroH
Synonyms
  • 5.4.99.5
  • aroG
Gene Name
aroH
Organism
Thermus thermophilus
Amino acid sequence
>lcl|BSEQ0011913|Chorismate mutase AroH
MVRGIRGAITVEEDTPEAIHQATRELLLKMLEANGIQSYEELAAVIFTVTEDLTSAFPAE
AARQIGMHRVPLLSAREVPVPGSLPRVIRVLALWNTDTPQDRVRHVYLREAVRLRPDLES
AQ
Number of residues
122
Molecular Weight
13649.555
Theoretical pI
5.68
GO Classification
Functions
chorismate mutase activity
Processes
aromatic amino acid family biosynthetic process / chorismate metabolic process
Components
cytoplasm
General Function
Chorismate mutase activity
Specific Function
Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis.
Pfam Domain Function
Transmembrane Regions
Not Available
Cellular Location
Cytoplasm
Gene sequence
>lcl|BSEQ0005312|369 bp
ATGGTCCGGGGCATCCGCGGCGCCATCACCGTGGAAGAGGACACCCCGGAGGCCATCCAC
CAGGCCACCCGGGAACTCCTCCTGAAGATGCTGGAGGCGAACGGCATCCAGAGCTACGAG
GAGCTCGCCGCCGTCATCTTCACCGTCACCGAGGACCTCACCTCCGCCTTCCCCGCCGAG
GCCGCGCGGCAGATCGGCATGCACCGGGTGCCCCTCCTCTCCGCCCGGGAGGTGCCGGTG
CCGGGAAGCCTCCCCCGGGTGATCCGCGTCCTCGCCCTCTGGAACACGGACACCCCCCAG
GACCGGGTGCGCCACGTCTACCTCAGGGAGGCGGTGCGGCTCCGGCCCGACCTGGAAAGC
GCCCAGTAG
Chromosome Location
Not Available
Locus
Not Available
External Identifiers
ResourceLink
UniProtKB IDQ84FH6
UniProtKB Entry NameAROH_THETH
GenBank Gene IDAY196198
General References
  1. Helmstaedt K, Heinrich G, Merkl R, Braus GH: Chorismate mutase of Thermus thermophilus is a monofunctional AroH class enzyme inhibited by tyrosine. Arch Microbiol. 2004 Mar;181(3):195-203. Epub 2004 Jan 15. [Article]

Drug Relations

Drug Relations
DrugBank IDNameDrug groupPharmacological action?ActionsDetails
DB02201Malonate IonexperimentalunknownDetails
DB038142-(N-morpholino)ethanesulfonic acidexperimentalunknownDetails