BMP-2-inducible protein kinase
Details
- Name
- BMP-2-inducible protein kinase
- Synonyms
- 2.7.11.1
- BIKE
- Gene Name
- BMP2K
- Organism
- Humans
- Amino acid sequence
>lcl|BSEQ0051706|BMP-2-inducible protein kinase MKKFSRMPKSEGGSGGGAAGGGAGGAGAGAGCGSGGSSVGVRVFAVGRHQVTLEESLAEG GFSTVFLVRTHGGIRCALKRMYVNNMPDLNVCKREITIMKELSGHKNIVGYLDCAVNSIS DNVWEVLILMEYCRAGQVVNQMNKKLQTGFTEPEVLQIFCDTCEAVARLHQCKTPIIHRD LKVENILLNDGGNYVLCDFGSATNKFLNPQKDGVNVVEEEIKKYTTLSYRAPEMINLYGG KPITTKADIWALGCLLYKLCFFTLPFGESQVAICDGNFTIPDNSRYSRNIHCLIRFMLEP DPEHRPDIFQVSYFAFKFAKKDCPVSNINNSSIPSALPEPMTASEAAARKSQIKARITDT IGPTETSIAPRQRPKANSATTATPSVLTIQSSATPVKVLAPGEFGNHRPKGALRPGNGPE ILLGQGPPQQPPQQHRVLQQLQQGDWRLQQLHLQHRHPHQQQQQQQQQQQQQQQQQQQQQ QQQQQQHHHHHHHHLLQDAYMQQYQHATQQQQMLQQQFLMHSVYQPQPSASQYPTMMPQY QQAFFQQQMLAQHQPSQQQASPEYLTSPQEFSPALVSYTSSLPAQVGTIMDSSYSANRSV ADKEAIANFTNQKNISNPPDMSGWNPFGEDNFSKLTEEELLDREFDLLRSNRLEERASSD KNVDSLSAPHNHPPEDPFGSVPFISHSGSPEKKAEHSSINQENGTANPIKNGKTSPASKD QRTGKKTSVQGQVQKGNDESESDFESDPPSPKSSEEEEQDDEEVLQGEQGDFNDDDTEPE NLGHRPLLMDSEDEEEEEKHSSDSDYEQAKAKYSDMSSVYRDRSGSGPTQDLNTILLTSA QLSSDVAVETPKQEFDVFGAVPFFAVRAQQPQQEKNEKNLPQHRFPAAGLEQEEFDVFTK APFSKKVNVQECHAVGPEAHTIPGYPKSVDVFGSTPFQPFLTSTSKSESNEDLFGLVPFD EITGSQQQKVKQRSLQKLSSRQRRTKQDMSKSNGKRHHGTPTSTKKTLKPTYRTPERARR HKKVGRRDSQSSNEFLTISDSKENISVALTDGKDRGNVLQPEESLLDPFGAKPFHSPDLS WHPPHQGLSDIRADHNTVLPGRPRQNSLHGSFHSADVLKMDDFGAVPFTELVVQSITPHQ SQQSQPVELDPFGAAPFPSKQ
- Number of residues
- 1161
- Molecular Weight
- 129170.91
- Theoretical pI
- Not Available
- GO Classification
- FunctionsAP-2 adaptor complex binding / ATP binding / phosphatase regulator activity / protein serine/threonine kinase activityProcessespositive regulation of Notch signaling pathway / protein phosphorylation / regulation of bone mineralization / regulation of clathrin-dependent endocytosisComponentscytoplasm / nuclear speck
- General Function
- May be involved in osteoblast differentiation.
- Specific Function
- Ap-2 adaptor complex binding
- Pfam Domain Function
- Transmembrane Regions
- Not Available
- Cellular Location
- Nucleus
- Gene sequence
>lcl|BSEQ0051707|BMP-2-inducible protein kinase (BMP2K) ATGAAGAAGTTCTCTCGGATGCCCAAGTCGGAGGGCGGCAGCGGCGGCGGAGCGGCGGGT GGCGGGGCTGGCGGGGCCGGGGCCGGGGCCGGCTGCGGCTCCGGCGGCTCGTCCGTGGGG GTCCGGGTGTTCGCGGTCGGCCGCCACCAGGTCACCCTGGAAGAGTCGCTGGCCGAAGGT GGATTCTCCACAGTTTTCCTCGTGCGTACTCACGGTGGAATCCGATGTGCATTGAAGCGA ATGTATGTCAATAACATGCCAGACCTCAATGTTTGTAAAAGGGAAATTACAATTATGAAA GAGCTATCTGGTCACAAAAATATTGTGGGCTATTTGGACTGTGCTGTTAATTCAATTAGT GATAATGTATGGGAAGTCCTTATCTTAATGGAATATTGTCGAGCTGGACAGGTAGTGAAT CAAATGAATAAGAAGCTACAGACGGGTTTTACAGAACCAGAAGTGTTACAGATATTCTGT GATACCTGTGAAGCTGTTGCAAGGTTGCATCAGTGTAAGACTCCAATAATTCACCGGGAT CTGAAGGTAGAAAATATTTTGTTGAATGATGGTGGGAACTATGTACTTTGTGACTTTGGC AGTGCCACTAATAAATTTCTTAATCCTCAAAAAGATGGAGTTAATGTAGTAGAAGAAGAA ATTAAAAAGTATACAACTCTGTCATACAGAGCCCCTGAAATGATCAACCTTTATGGAGGG AAACCCATCACCACCAAGGCTGATATCTGGGCACTGGGATGTCTACTCTATAAACTTTGT TTCTTCACTCTTCCTTTTGGTGAGAGTCAGGTTGCTATCTGTGATGGCAACTTCACCATC CCAGACAATTCTCGTTACTCCCGTAACATACATTGCTTAATAAGGTTCATGCTTGAACCA GATCCGGAACATAGACCTGATATATTTCAAGTGTCATATTTTGCATTTAAATTTGCCAAA AAGGATTGTCCAGTCTCCAACATCAATAATTCTTCTATTCCTTCAGCTCTTCCTGAACCG ATGACTGCTAGTGAAGCAGCTGCTAGGAAAAGCCAAATAAAAGCCAGAATAACAGATACC ATTGGACCAACAGAAACCTCAATTGCACCAAGACAAAGACCAAAGGCCAACTCTGCTACT ACTGCCACTCCCAGTGTGCTGACCATTCAAAGTTCAGCAACACCTGTTAAAGTCCTTGCT CCTGGTGAATTCGGTAACCATAGACCAAAAGGGGCACTAAGACCTGGAAATGGCCCTGAA ATTTTATTGGGTCAGGGACCTCCTCAGCAGCCGCCACAGCAGCATAGAGTACTCCAGCAA CTACAGCAGGGAGATTGGAGATTACAGCAACTCCATTTACAGCATCGTCATCCTCACCAG CAGCAGCAGCAGCAGCAGCAGCAACAGCAACAGCAGCAGCAGCAACAGCAACAGCAGCAG CAGCAGCAGCAGCAGCAGCACCACCACCACCACCACCACCACCTACTTCAAGATGCTTAT ATGCAGCAGTATCAACATGCAACACAGCAGCAACAGATGCTTCAACAACAATTTTTAATG CATTCGGTATATCAACCACAACCTTCTGCATCACAGTATCCTACAATGATGCCGCAGTAT CAGCAGGCTTTCTTTCAACAGCAGATGCTAGCTCAACATCAGCCGTCTCAACAACAGGCA TCACCTGAATATCTTACCTCCCCTCAAGAGTTCTCACCAGCCTTAGTTTCCTACACTTCA TCACTTCCAGCTCAGGTTGGAACCATAATGGACTCCTCCTATAGTGCCAATAGGTCAGTT GCTGATAAAGAGGCCATTGCAAATTTCACAAATCAGAAGAACATCAGCAATCCACCTGAT ATGTCAGGGTGGAATCCTTTTGGAGAGGATAATTTCTCTAAGTTAACAGAAGAGGAACTA TTGGACAGAGAATTTGACCTTCTAAGATCAAATAGGCTCGAGGAGAGAGCATCCTCAGAT AAGAATGTAGACTCACTTTCTGCTCCACATAACCATCCTCCAGAAGATCCTTTTGGTTCT GTTCCTTTCATTTCTCATTCAGGTTCTCCTGAAAAGAAAGCTGAACATTCATCTATAAAT CAAGAAAATGGCACTGCAAACCCTATCAAGAACGGTAAAACAAGTCCAGCATCTAAAGAT CAGCGGACTGGAAAGAAAACCTCAGTACAGGGTCAAGTGCAAAAGGGGAATGATGAATCT GAAAGTGATTTTGAATCAGATCCCCCTTCTCCTAAGAGCAGTGAAGAGGAAGAGCAAGAT GATGAAGAAGTTCTTCAGGGGGAACAAGGAGATTTTAATGATGATGATACTGAACCAGAA AATCTGGGTCATAGGCCTCTCCTCATGGATTCTGAAGATGAGGAAGAAGAGGAGAAACAT AGCTCTGATTCTGATTATGAGCAGGCTAAAGCAAAGTACAGTGACATGAGCTCTGTCTAC AGAGACAGATCTGGCAGTGGACCAACCCAAGATCTTAATACAATACTCCTCACCTCAGCC CAATTATCCTCTGATGTTGCAGTGGAGACTCCCAAACAGGAGTTTGATGTATTTGGCGCT GTCCCCTTCTTTGCAGTGCGTGCTCAACAGCCCCAGCAAGAAAAGAATGAAAAGAACCTC CCTCAACACAGGTTTCCTGCTGCAGGACTGGAGCAGGAGGAATTTGATGTATTCACAAAG GCGCCTTTTAGCAAGAAGGTGAATGTACAAGAATGCCATGCAGTGGGGCCTGAGGCACAT ACTATCCCTGGTTATCCCAAAAGTGTAGATGTATTTGGCTCCACTCCATTTCAGCCCTTC CTCACATCAACAAGTAAAAGTGAAAGCAATGAGGACCTTTTTGGGCTTGTGCCCTTTGAT GAAATAACGGGGAGCCAGCAGCAAAAAGTCAAACAGCGCAGCTTACAGAAACTGTCCTCT CGCCAAAGGCGCACAAAGCAGGATATGTCCAAAAGTAATGGGAAGCGGCATCATGGCACG CCAACTAGCACAAAGAAGACTTTGAAGCCTACCTATCGCACTCCAGAGAGGGCTCGCAGG CACAAAAAAGTGGGCCGCCGAGACTCTCAAAGTAGCAATGAATTTTTAACCATCTCAGAC TCCAAGGAGAACATTAGTGTTGCACTGACTGATGGGAAAGATAGGGGGAATGTCTTACAA CCTGAGGAGAGCCTGTTGGACCCCTTCGGTGCCAAGCCCTTCCATTCTCCAGACCTGTCA TGGCACCCTCCACATCAGGGCCTGAGCGACATCCGTGCTGATCACAATACTGTCCTGCCA GGGCGGCCAAGACAAAATTCACTACATGGGTCATTCCATAGTGCAGATGTATTGAAAATG GATGATTTTGGTGCCGTGCCCTTTACAGAACTTGTGGTGCAAAGCATCACTCCACATCAG TCCCAACAGTCCCAACCAGTCGAATTAGACCCATTTGGTGCTGCTCCATTTCCTTCTAAA CAGTAG
- Chromosome Location
- 4
- Locus
- 4q21.21
- External Identifiers
Resource Link UniProtKB ID Q9NSY1 UniProtKB Entry Name BMP2K_HUMAN HGNC ID HGNC:18041 - General References
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