Benzopyrans

Name
Benzopyrans
Accession Number
DBCAT000370
Description

Compounds with a core of fused benzo-pyran rings.

Drugs
DrugDrug Description
Vitamin EAn antioxidant vitamin used in many skin creams and multivitamin preparations.
MethoxsalenA furocoumarin used to treat psoriasis and vitiligo.
TrioxsalenA psoralen derivative that has been used in combination with UV light to treat vitiligo, but has been discontinued by its manufacturer.
NebivololA beta blocking agent used to treat hypertension and aid in the management of heart failure.
Ellagic acidEllagic acid is being investigated for use in follicular lymphoma, brain injury in intrauterine growth restricted babies, obese adolescents, and solar lentigines.
DiosminA citrus flavonoid medication used to support vascular health.
Maritime pine extractA plant extract in nutritional supplements for healthy hair, skin, and nails.
DicoumarolFor decreasing blood clotting. Often used along with heparin for treatment of deep vein thrombosis.
PranlukastA leukotriene receptor antagonist for the treatment of allergic rhinitis and asthma symptoms.
MyricetinNot Available
LY-294002Specific inhibitor of phosphatidylinositol 3-kinase.
4-hydroxycoumarinNot Available
AlvocidibInvestigated for use/treatment in esophageal cancer, leukemia (lymphoid), lung cancer, liver cancer, and lymphoma (unspecified).
CoumarinNot Available
SF1126For the treatment of various forms of cancer.
SB-743921Investigated for use/treatment in cancer/tumors (unspecified) and lymphoma (non-hodgkin's).
alpha-NaphthoflavoneNot Available
FlavoneNot Available
Coumarin 120Not Available
TricetinNot Available
SakuranetinNot Available
DiosmetinDiosmetin is an O-methylated flavone and the aglycone part of the flavonoid glycosides diosmin that occurs naturally in citrus fruits . Pharmacologically, diosmetin is reported to exhibit anticancer, antimicrobial, antioxidant,...
IcariinIcariin has been investigated for the basic science of the Pharmacokinetic Profile of Icariin in Humans.
RecoflavoneRecoflavone has been used in trials studying the treatment of Acute Gastritis, Dry Eye Syndrome, and Chronic Gastritis.
IguratimodIguratimod is under investigation in Rheumatoid Arthritis.
IcaritinIcaritin has been used in trials studying the treatment of Solid Tumors, Metastatic Breast Cancer, and Hepatocellular Carcinoma (HCC).
TecarfarinTecarfarin has been used in trials studying the prevention of Thrombosis and Thromboembolism.
EfloxateNot Annotated
TioclomarolNot Annotated
DimeflineNot Annotated
Citrus bioflavonoidsNot Annotated
AZD-8186AZD-8186 is under investigation in clinical trial NCT03218826 (PI3Kbeta Inhibitor AZD8186 and Docetaxel in Treating Patients Advanced Solid Tumors With PTEN or PIK3CB Mutations That Are Metastatic or Cannot Be...
AvutometinibAvutometinib (RO-5126766 free base) is under investigation in clinical trial NCT03875820 (Phase I Trial of VS-6063 and RO5126766.).
XanthohumolXanthohumol is under investigation in clinical trial NCT01367431 (Xanthohumol and Metabolic Syndrome).
Urolithin AUrolithin A is a metabolite of ellagic acid. It has been demonstrated to stimulate mitophagy and improve muscle health in old animals and in preclinical models of aging.
ChrysinNot Annotated
DihydromyricetinDihydromyricetin is under investigation in clinical trial NCT03606694 (Effect of Dihydromirycetin on Glycemic Control, Insulin Sensitivity and Insulin Secretion in Type 2 Diabetes Mellitus).
TroglitazoneFor the treatment of Type II diabetes mellitus. It is used alone or in combination with a sulfonylurea, metformin, or insulin as an adjunct to diet and exercise.
PhenprocoumonAn anticoagulant drug used for the prevention of thrombosis.
Cromoglicic acidA medication used to treat asthma, allergic reactions of the eyes and nose, as well as other mast cell reactions.
NovobiocinFor the treatment of infections due to staphylococci and other susceptible organisms
HesperetinFor lowering cholesterol and, possibly, otherwise favorably affecting lipids. In vitro research also suggests the possibility that hesperetin might have some anticancer effects and that it might have some anti-aromatase...
FlavoxateA muscarinic antagonist and spasmolytic used for the symptomatic relief of conditions associated with lack of muscle control in the bladder, such as dysuria, urgency, and nocturia.
AcenocoumarolAn anticoagulant drug used in the prevention of thromboembolic diseases in infarction and transient ischemic attacks, as well as management of deep vein thrombosis and myocardial infarction.
GenisteinCurrently Genistein is being studied in clinical trials as a treatment for prostate cancer.
RutinA flavonoid found in over-the-counter vitamin supplements.
DaidzinNot Available
TaxifolinNot Available
4-methyl-umbelliferyl-N-acetyl-chitobioseNot Available
IsoliquiritigeninIsoliquiritigenin is a precursor to several flavonones in many plants.
NaringeninNot Available
EpigallocatechinNot Available
ClorobiocinClorobiocin is an aminocoumarin antibiotic, similar to novobiocin and coumermycin A1.
IsoformononetinNot Available
QuercetinA natural flavonoid found in foods and natural supplement products.
4'-HydroxyflavanoneNot Available
3,4-DichloroisocoumarinNot Available
HesperidinA bioflavonoid found in a variety of nutritional supplements that is touted to have various beneficial effects on blood vessel disorders and various other conditions.
Calanolide AFor use in combination treatment of HIV infection (AIDS).
IdronoxilIntended for the treatment of various forms of cancer.
CrofelemerAn antidiarrheal agent used for the symptomatic relief of drug-induced non-infectious diarrhea in adult patients with HIV/AIDS receiving antiretroviral therapy.
ElafibranorInvestigated for use/treatment in atherosclerosis and diabetes mellitus type 2.
SofalconeInvestigated for use/treatment in gastroenteritis and ulcers.
TriphendiolInvestigated for use/treatment in cancer/tumors (unspecified).
beta-Naphthoflavoneβ-Naphthoflavone, also known as 5,6-benzoflavone, is a potent agonist of the aryl hydrocarbon receptor and induces cytochromes P450 (CYPs) and uridine 5'-diphospho-glucuronosyltransferases (UGTs). It may be a chemopreventive agent.
Bisphenol ANot Available
HymecromoneA coumarin derivative that lacks anticoagulant properties but possesses choleretic and biliary antispasmodic activity.
ApigeninNot Available
FisetinNot Available
PhloretinPhloretin is a natural dihydrochalcone found in apples and many other fruits.
Ethyl biscoumacetateEthyl biscoumacetate is a courmarin that is used as an anticoagulant. It has actions similar to those of Warfarin. (From Martindale, The Extra Pharmacopoeia, 30th ed, p226)
SilibininA flavonolignan with hepatoprotective effects used to treat toxic liver damage and as an adjunct in the management of chronic conditions such as cirrhosis and hepatitis.
TocopherolTocopherol can be used as a dietary supplement for patients with a deficit of vitamin E; this is mainly prescribed in the alpha form. Vitamin E deficiency is rare, and...
CoumaphosThis drug is a fat-soluble phosphorothioate agent that kills both insects and mites. It is non-volatile in nature and is well known by a variety of names as such a...
HaloxonNot Annotated
RotenoneRotenone is an isoflavone compound that naturally occurs in the jicama vine plant as well as many Fabaceae plants. It has broad spectrum insecticide and pesticide activity and is also...
TocofersolanA derivative of alpha tocopherol used to treat vitamin E deficiencies.
EquolEquol has been used in trials studying the treatment of Breast Cancer.
IsoflavoneA biologically active phytoestrogen found in high concentrations in soy and other legumes.
EpicatechinEpicatechin has been used in trials studying the treatment of Pre-diabetes.
Epigallocatechin gallateEpigallocatechin gallate has been investigated for the treatment of Hypertension and Diabetic Nephropathy.
BergaptenBergapten is under investigation in clinical trial NCT00533195 (Comparison of UVA1 Phototherapy Versus Photochemotherapy for Patients With Severe Generalized Atopic Dermatitis).
PuerarinPuerarin has been investigated for the treatment of Alcohol Abuse.
TocotrienolTocotrienol has been investigated for the treatment of Cholesterol Lowering.
IsoquercetinIsoquercetin has been used in trials studying the treatment of Kidney Cancer, Renal cell carcinoma, Advanced Renal Cell Carcinoma, Thromboembolism of Vein in Pancreatic Cancer, and Thromboembolism of Vein VTE...
CP-195543CP-195,543 has been used in trials studying the treatment of Arthritis, Rheumatoid.
ME-344ME-344 has been used in trials studying the treatment of Solid Tumors.
ChromanolChromanol has been used in trials studying the treatment of Prostate Cancer.
TroxerutinTroxerutin has been used in trials studying the treatment of Chronic Venous Insufficiency.
EsculinAs medication, esculin is sometimes used as a vasoprotective agent. Esculin is also used in a microbiology laboratory to aid in the identification of bacterial species (especially Enterococci and Listeria),...
4-methylumbelliferyl beta-D-glucosideNot Annotated
DaidzeinNot Annotated
CarbocromenCarbocromen was marketed for use in Germany as a vasodilator, however, it has been discontinued due to the risk of arrhythmia development .
VisnadineNot Annotated
CloricromenNot Annotated
HidrosminA synthetic bioflavonoid used for the short-term treatment of symptoms associated with chronic venous insufficiency.
IpriflavoneNot Annotated
Coumermycin A1Not Annotated
alpha-Tocopherol succinateA form of vitamin E used to treat and prevent vitamin deficiencies.
D-alpha-Tocopherol acetateA form of vitamin E used to treat and prevent vitamin deficiencies.
alpha-Tocopherol acetateA form of vitamin E used to treat and prevent vitamin deficiencies.
HispidulinHispidulin (4',5,7-trihydroxy-6-methoxyflavone) is a potent benzodiazepine (BZD) receptor ligand with positive allosteric properties .
CianidanolAn antioxidant flavonoid, occurring especially in woody plants as both (+)-catechin and (-)-epicatechin (cis) forms.
TocopherylquinoneNot Annotated
DihydroxymethoxychalconeCardamonin (also known as Dihydroxymethoxychalcone), as shown by the increasing number of publications, has received growing attention from the scientific community due to the expectations toward its benefits to human...
BilberryNot Annotated
Biochanin ABiochanin A is under investigation in clinical trial NCT02174666 (Isoflavone Treatment for Postmenopausal Osteopenia.).
FormononetinFormononetin is under investigation in clinical trial NCT02174666 (Isoflavone Treatment for Postmenopausal Osteopenia.).
gamma-Tocopherolgamma-Tocopherol is under investigation in clinical trial NCT00836368 (In Vitro Basophil Responsiveness to Allergen Challenge After Gamma-tocopherol Supplementation in Allergic Asthmatics).
LuteolinNot Annotated
Tocopheryl nicotinateA vitamin E supplement indicated in the treatment of high cholesterol and narrowing of peripheral arteries.
Hesperidin methylchalconeNot Annotated
BaicaleinBaicalein is under investigation in clinical trial NCT03830684 (A Randomized, Double-blind, Placebo-controlled, Multicenter and Phase ⅡA Clinical Trial for the Effectiveness and Safety of Baicalein Tablets in the Treatment of...
Epigallo Catechin GallateEpigallo Catechin Gallate is under investigation in clinical trial NCT00799890 (Sunphenon in Progressive Forms of Multiple Sclerosis).
IsoquercitrinIsoquercitrin is under investigation in clinical trial NCT04622865 (Masitinib Combined With Isoquercetin and Best Supportive Care in Hospitalized Patients With Moderate and Severe COVID-19).
IsorhamnetinNot Annotated
MorinNot Annotated
RhamnetinNot Annotated
VitexinNot Annotated
NaringinNot Annotated
HematoxylinNot Annotated
EupatilinNot Annotated
OrmeloxifeneA selective estrogen receptor modulator used as a non-hormonal, non-steroidal oral contraceptive.
PD-98059PD-98059 is an inhibitor of MAP-kinase kinase activation.
TRX-E-002-1Not Annotated
ChrysoeriolNot Annotated
SonlicromanolSonlicromanol is under investigation in clinical trial NCT04165239 (The KHENERGYZE Study).
AmotosalenNot Available
SinecatechinsA topical agent used to treat external genital and perianal warts in immunocompetent adult patients.
PsoralenNot Annotated
Nanaomycin DNot Available
Granaticin BNot Annotated
Drugs & Drug Targets
DrugTargetType
Vitamin ESEC14-like protein 4target
Vitamin ESEC14-like protein 3target
Vitamin ESEC14-like protein 2target
Vitamin ENuclear receptor subfamily 1 group I member 2target
Vitamin EProtein kinase C beta typetarget
Vitamin EArachidonate 5-lipoxygenasetarget
Vitamin EProtein kinase C alpha typetarget
Vitamin EDiacylglycerol kinase alphatarget
Vitamin ESerine/threonine-protein phosphatase 2A catalytic subunit beta isoformtarget
Vitamin ESerine/threonine-protein phosphatase 2A catalytic subunit alpha isoformtarget
Vitamin EAlpha-tocopherol transfer proteincarrier
Vitamin EGlutathione S-transferase A2enzyme
Vitamin EGlutathione S-transferase Penzyme
Vitamin EGlutathione S-transferase omega-1enzyme
Vitamin EGlutathione S-transferase Mu 3enzyme
Vitamin EGlutamate--cysteine ligase catalytic subunitenzyme
Vitamin ENAD(P)H dehydrogenase [quinone] 1enzyme
Vitamin EHeme oxygenase 1enzyme
Vitamin ESuperoxide dismutase [Cu-Zn]enzyme
Vitamin EScavenger receptor class B member 1transporter
Vitamin EATP-binding cassette sub-family A member 1transporter
Vitamin ENiemann-Pick C1-like protein 1transporter
Vitamin EATP-binding cassette sub-family G member 1transporter
Vitamin ESEC14-like protein 2carrier
Vitamin ESEC14-like protein 3carrier
Vitamin EPhospholipid transfer proteincarrier
Vitamin ECytochrome P450 3A4enzyme
MethoxsalenDNAtarget
MethoxsalenCytochrome P450 2A6enzyme
MethoxsalenCytochrome P450 1A2enzyme
MethoxsalenCytochrome P450 1A1enzyme
MethoxsalenCytochrome P450 2A13enzyme
TrioxsalenDNAtarget
NebivololBeta-1 adrenergic receptortarget
NebivololCytochrome P450 2D6enzyme
NebivololBeta-2 adrenergic receptortarget
NebivololCytochrome P450 3A4enzyme
NebivololSerum albumincarrier
NebivololBeta-3 adrenergic receptortarget
NebivololCytochrome P450 2C19enzyme
Ellagic acidSolute carrier family 22 member 6transporter
Ellagic acidSolute carrier family 22 member 11transporter
Ellagic acidCytochrome P450 1A1enzyme
Ellagic acidCytochrome P450 2E1enzyme
Ellagic acidCarbonic anhydrase 1target
Ellagic acidCarbonic anhydrase 2target
Ellagic acidCarbonic anhydrase 3target
Ellagic acidCarbonic anhydrase 4target
Ellagic acidCarbonic anhydrase 5A, mitochondrialtarget
Ellagic acidCarbonic anhydrase 5B, mitochondrialtarget
Ellagic acidCarbonic anhydrase 6target
Ellagic acidCarbonic anhydrase 7target
Ellagic acidCarbonic anhydrase 9target
Ellagic acidCarbonic anhydrase 12target
Ellagic acidCarbonic anhydrase 14target
Ellagic acidCasein kinase II subunit alphatarget
Ellagic acidcAMP-dependent protein kinase catalytic subunit alphatarget
Ellagic acidProtein kinase C alpha typetarget
Ellagic acidProtein kinase C beta typetarget
Ellagic acidTyrosine-protein kinase SYKtarget
Ellagic acidSqualene monooxygenasetarget
DiosminAryl hydrocarbon receptortarget
DiosminSerum albumincarrier
DiosminP-glycoprotein 1transporter
DiosminSolute carrier organic anion transporter family member 1B1transporter
DiosminSolute carrier organic anion transporter family member 1B3transporter
DiosminSolute carrier organic anion transporter family member 2B1transporter
DiosminCytochrome P450 1A1enzyme
DiosminCytochrome P450 2C9enzyme
DiosminCytochrome P450 2E1enzyme
DiosminCytochrome P450 3A4enzyme
DicoumarolVitamin K epoxide reductase complex subunit 1target
DicoumarolNAD(P)H dehydrogenase [quinone] 1target
DicoumarolQuinone oxidoreductasetarget
DicoumarolCytochrome P450 2C9enzyme
DicoumarolSerum albumincarrier
DicoumarolCytochrome P450 2C6enzyme
DicoumarolCytochrome P450 2C11enzyme
PranlukastTumor necrosis factortarget
PranlukastInterleukin-5target
PranlukastEosinophil cationic proteintarget
PranlukastNuclear factor NF-kappa-B p105 subunittarget
PranlukastMucin-2target
PranlukastCysteinyl leukotriene receptor 1target
PranlukastCytochrome P450 3A4enzyme
PranlukastCanalicular multispecific organic anion transporter 1transporter
PranlukastCytochrome P450 2C9enzyme
PranlukastNuclear factor NF-kappa-Btarget
MyricetinPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoformtarget
MyricetinMultidrug resistance-associated protein 1transporter
MyricetinTyrosine-protein kinase JAK1target
LY-294002Serine/threonine-protein kinase pim-1target
LY-294002Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoformtarget
4-hydroxycoumarinMajor NAD(P)H-flavin oxidoreductasetarget
AlvocidibGlycogen phosphorylase, muscle formtarget
AlvocidibCyclin-dependent kinase 7target
AlvocidibCyclin-dependent kinase 5target
AlvocidibCyclin-dependent kinase 9target
AlvocidibCyclin-dependent kinase 1target
AlvocidibCyclin-dependent kinase 6target
AlvocidibEpidermal growth factor receptortarget
AlvocidibCyclin-dependent kinase 4target
AlvocidibCyclin-dependent kinase 8target
AlvocidibCyclin-dependent kinase 2target
AlvocidibATP-binding cassette sub-family G member 2transporter
AlvocidibGlycogen phosphorylase, brain formtarget
AlvocidibGlycogen phosphorylase, liver formtarget
AlvocidibUDP-glucuronosyltransferase 1-1enzyme
CoumarinCytochrome P450 2A6target
CoumarinCytochrome P450 2C9enzyme
SF1126Phosphatidylinositol 3-kinase regulatory subunit alphatarget
SF1126Phosphatidylinositol 3-kinase regulatory subunit betatarget
SF1126Phosphatidylinositol 3-kinase regulatory subunit gammatarget
SF1126DNA-dependent protein kinase catalytic subunittarget
SF1126Serine/threonine-protein kinase mTORtarget
alpha-NaphthoflavoneCytochrome P450 1A2target
FlavoneNeocarzinostatintarget
FlavoneSteroid hormone receptor ERR1target
FlavoneSteroid hormone receptor ERR2target
FlavoneCytochrome P450 1B1target
Coumarin 120Peptidyl-prolyl cis-trans isomerase Atarget
Coumarin 120Peptidyl-prolyl cis-trans isomerase F, mitochondrialtarget
Coumarin 120Histone deacetylase 8target
TricetinSerine/threonine-protein kinase pim-1target
Sakuranetin3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZtarget
TroglitazonePeroxisome proliferator-activated receptor gammatarget
TroglitazoneLong-chain-fatty-acid--CoA ligase 4target
TroglitazonePlasminogen activator inhibitor 1target
TroglitazoneEquilibrative nucleoside transporter 1target
TroglitazoneCytochrome P450 3A4enzyme
TroglitazoneCytochrome P450 2C19enzyme
TroglitazoneUDP-glucuronosyltransferase 1-1enzyme
TroglitazoneCytochrome P450 2C8enzyme
TroglitazoneBile salt export pumptransporter
TroglitazoneSolute carrier organic anion transporter family member 1B1transporter
TroglitazoneEstrogen-related receptor gammatarget
TroglitazoneSteroid hormone receptor ERR1target
TroglitazoneCytochrome P450 19A1enzyme
TroglitazoneCytochrome P450 1A1enzyme
TroglitazoneCytochrome P450 2B6enzyme
TroglitazoneCytochrome P450 2C9enzyme
TroglitazoneCytochrome P450 3A5enzyme
TroglitazoneCytochrome P450 3A7enzyme
TroglitazoneUDP-glucuronosyltransferase 1-3enzyme
TroglitazoneUDP-glucuronosyltransferase 1-4enzyme
TroglitazoneUDP-glucuronosyltransferase 1-6enzyme
TroglitazoneUDP-glucuronosyltransferase 1-7enzyme
TroglitazoneUDP-glucuronosyltransferase 1-8enzyme
TroglitazoneUDP-glucuronosyltransferase 1-9enzyme
TroglitazoneUDP-glucuronosyltransferase 1-10enzyme
TroglitazoneUDP-glucuronosyltransferase 2B7enzyme
TroglitazoneUDP-glucuronosyltransferase 2B15enzyme
TroglitazonePeroxisome proliferator-activated receptor deltatarget
TroglitazonePeroxisome proliferator-activated receptor alphatarget
TroglitazoneGlutathione S-transferase Ptarget
PhenprocoumonVitamin K epoxide reductase complex subunit 1target
PhenprocoumonAlpha-1-acid glycoprotein 1carrier
PhenprocoumonSerum albumincarrier
PhenprocoumonCytochrome P450 2C9enzyme
PhenprocoumonCytochrome P450 3A4enzyme
PhenprocoumonCytochrome P450 2C8enzyme
Cromoglicic acidProtein S100-Ptarget
NovobiocinDNA gyrase subunit Btarget
NovobiocinSolute carrier family 22 member 6transporter
NovobiocinSolute carrier family 22 member 8transporter
NovobiocinSolute carrier family 22 member 11transporter
NovobiocinATP-binding cassette sub-family G member 2transporter
NovobiocinDNA topoisomerase 1target
NovobiocinSolute carrier organic anion transporter family member 1B1transporter
NovobiocinSolute carrier organic anion transporter family member 1B3transporter
NovobiocinSolute carrier organic anion transporter family member 2B1transporter
HesperetinMicrosomal triglyceride transfer protein large subunittarget
HesperetinSterol O-acyltransferase 1target
HesperetinSterol O-acyltransferase 2target
HesperetinCytochrome P450 1A2enzyme
HesperetinATP-binding cassette sub-family G member 2transporter
HesperetinSex hormone-binding globulintarget
FlavoxateMuscarinic acetylcholine receptor M1target
FlavoxateMuscarinic acetylcholine receptor M2target
AcenocoumarolVitamin K epoxide reductase complex subunit 1target
AcenocoumarolCytochrome P450 2C9enzyme
AcenocoumarolCytochrome P450 1A2enzyme
AcenocoumarolSerum albumincarrier
AcenocoumarolAlpha-1-acid glycoprotein 1carrier
AcenocoumarolCytochrome P450 2C19enzyme
AcenocoumarolCytochrome P450 3A4enzyme
AcenocoumarolP-glycoprotein 1transporter
GenisteinEstrogen receptor betatarget
GenisteinDNA topoisomerase 2-alphatarget
GenisteinProtein-tyrosine kinase 2-betatarget
GenisteinP-glycoprotein 1transporter
GenisteinMultidrug resistance-associated protein 1transporter
GenisteinATP-binding cassette sub-family G member 2transporter
GenisteinCytochrome P450 1A2enzyme
GenisteinNuclear receptor coactivator 1target
GenisteinEstrogen receptor alphatarget
GenisteinNuclear receptor coactivator 2target
GenisteinTransthyretincarrier
GenisteinSteroid hormone receptor ERR2target
GenisteinSteroid hormone receptor ERR1target
GenisteinNuclear receptor subfamily 1 group I member 2target
GenisteinRAC-alpha serine/threonine-protein kinasetarget
GenisteinG-protein coupled estrogen receptor 1target
GenisteinCytochrome P450 1B1target
GenisteinSex hormone-binding globulintarget
GenisteinCytochrome P450 1A1enzyme
GenisteinSolute carrier organic anion transporter family member 1B1transporter
GenisteinSolute carrier organic anion transporter family member 2B1transporter
GenisteinCytochrome P450 2C8enzyme
GenisteinCytochrome P450 2C9enzyme
GenisteinCytochrome P450 3A1enzyme
GenisteinCytochrome P450 3A2enzyme
GenisteinCytochrome P450 3A4enzyme
GenisteinCystic fibrosis transmembrane conductance regulatortarget
RutinAldo-keto reductase family 1 member C3target
RutinCytochrome P450 3A4enzyme
RutinCarbonyl reductase [NADPH] 1target
DaidzinAldehyde dehydrogenase, mitochondrialtarget
DaidzinATP-binding cassette sub-family G member 2transporter
4-methyl-umbelliferyl-N-acetyl-chitobioseLysozyme Ctarget
NaringeninSolute carrier organic anion transporter family member 2B1transporter
NaringeninP-glycoprotein 1transporter
NaringeninMultidrug resistance-associated protein 1transporter
NaringeninATP-binding cassette sub-family G member 2transporter
NaringeninHTH-type transcriptional regulator TtgRtarget
NaringeninEstrogen receptor alphatarget
NaringeninAldo-keto reductase family 1 member C1target
NaringeninCytochrome P450 1B1target
NaringeninKAT8 regulatory NSL complex subunit 3target
NaringeninSex hormone-binding globulintarget
NaringeninCytochrome P450 19A1target
NaringeninEstrogen receptor betatarget
ClorobiocinDNA gyrase subunit Btarget
QuercetinTyrosine-protein kinase HCKtarget
QuercetinCytochrome P450 2C8enzyme
QuercetinMultidrug resistance-associated protein 1transporter
QuercetinCanalicular multispecific organic anion transporter 1transporter
QuercetinMonocarboxylate transporter 2transporter
QuercetinSolute carrier organic anion transporter family member 2B1transporter
QuercetinP-glycoprotein 1transporter
QuercetinMonocarboxylate transporter 1transporter
QuercetinATP-binding cassette sub-family G member 2transporter
QuercetinPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoformtarget
QuercetinUDP-glucuronosyltransferase 3A1target
QuercetinATP synthase subunit alpha, mitochondrialtarget
QuercetinATP synthase subunit beta, mitochondrialtarget
QuercetinATP synthase subunit gamma, mitochondrialtarget
QuercetinSerine/threonine-protein kinase pim-1target
QuercetinHTH-type transcriptional regulator TtgRtarget
Quercetin3-hydroxyisobutyryl-CoA hydrolase, mitochondrialtarget
Quercetin3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZtarget
QuercetinSerine/threonine-protein kinase 17Btarget
QuercetinEstrogen receptor alphatarget
QuercetinEstrogen receptor betatarget
QuercetinRibosyldihydronicotinamide dehydrogenase [quinone]target
QuercetinSerum albumincarrier
QuercetinAryl hydrocarbon receptortarget
QuercetinCytochrome P450 1B1target
QuercetinActin, cytoplasmic 1target
QuercetinCasein kinase II subunit alphatarget
QuercetinCasein kinase II subunit betatarget
QuercetinEukaryotic translation initiation factor 3 subunit Ftarget
QuercetinHeat shock protein HSP 90-alphatarget
QuercetinHeat shock-related 70 kDa protein 2target
QuercetinRuvB-like 2target
QuercetinSplicing factor 3B subunit 3target
QuercetinUbiquitin-like modifier-activating enzyme 1target
QuercetinSex hormone-binding globulintarget
QuercetinCarbonyl reductase [NADPH] 1target
QuercetinCCAAT/enhancer-binding protein betatarget
QuercetinNuclear receptor subfamily 1 group I member 2target
QuercetinSolute carrier organic anion transporter family member 1B1transporter
QuercetinCytochrome P450 2C9enzyme
QuercetinCytochrome P450 1A2enzyme
QuercetinCytochrome P450 2E1enzyme
QuercetinCytochrome P450 2C19enzyme
QuercetinCytochrome P450 3A Subfamilyenzyme
QuercetinCytochrome P450 2D6enzyme
4'-HydroxyflavanoneSex hormone-binding globulintarget
3,4-DichloroisocoumarinComplement factor Dtarget
HesperidinAurora kinase Btarget
Calanolide AGag-Pol polyproteintarget
Calanolide ACytochrome P450 3A4enzyme
IdronoxilEcto-NOX disulfide-thiol exchanger 2target
CrofelemerCystic fibrosis transmembrane conductance regulatortarget
CrofelemerAnoctamin-1target
ElafibranorPeroxisome proliferator-activated receptor alphatarget
ElafibranorPeroxisome proliferator-activated receptor deltatarget
ElafibranorPeroxisome proliferator-activated receptor gammatarget
SofalconeCarbonyl reductase [NADPH] 1enzyme
beta-NaphthoflavoneCytochrome P450 1A2enzyme
beta-NaphthoflavoneEstrogen receptor alphatarget
beta-NaphthoflavoneSteroid hormone receptor ERR1target
beta-NaphthoflavoneCOUP transcription factor 1target
beta-NaphthoflavoneAryl hydrocarbon receptortarget
beta-NaphthoflavoneCytochrome P450 1B1target
Bisphenol AEstrogen-related receptor gammatarget
HymecromoneArylsulfate sulfotransferasetarget
Apigenin3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZtarget
FisetinCyclin homologtarget
FisetinCyclin-dependent kinase 6target
PhloretinHTH-type transcriptional regulator TtgRtarget
Ethyl biscoumacetateGlutamine synthetaseenzyme
Ethyl biscoumacetateCytochrome P450 3A4enzyme
SilibininSolute carrier family 22 member 6transporter
SilibininUDP-glucuronosyltransferase 1-1enzyme
SilibininSolute carrier organic anion transporter family member 1B1transporter
SilibininSolute carrier organic anion transporter family member 1B3transporter
SilibininSolute carrier organic anion transporter family member 2B1transporter
TocopherolFree radicalstarget
TocopherolLeukotriene-B(4) omega-hydroxylase 1enzyme
TocopherolCytochrome P450 3A4enzyme
TocopherolVery low-density lipoprotein receptorcarrier
TocopherolLow-density lipoprotein receptorcarrier
TocopherolAlpha-tocopherol transfer proteintransporter
TocopherolSEC14-like protein 4transporter
TocopherolSEC14-like protein 2transporter
TocopherolSEC14-like protein 3transporter
TocopherolApolipoprotein B receptortransporter
TocopherolScavenger receptor class B member 1transporter
TocopherolP-glycoprotein 1transporter
TocofersolanP-glycoprotein 1target
TocofersolanLeukotriene-B(4) omega-hydroxylase 1enzyme
TocofersolanAlpha-tocopherol transfer proteintransporter
TocofersolanScavenger receptor class B member 1transporter
TocofersolanNiemann-Pick C1-like protein 1transporter
TocofersolanATP-binding cassette sub-family G member 5transporter
TocofersolanATP-binding cassette sub-family G member 8transporter
TocofersolanATP-binding cassette sub-family A member 1transporter
TocofersolanSEC14-like protein 4transporter
TocofersolanSEC14-like protein 2transporter
TocofersolanSEC14-like protein 3transporter
TocofersolanApolipoprotein B receptortransporter
TocofersolanCytochrome P450 3A4enzyme
EquolEstrogen receptor betatarget
EquolSex hormone-binding globulintarget
IsoflavonePeroxisome proliferator-activated receptor alphatarget
IsoflavonePeroxisome proliferator-activated receptor gammatarget
Epigallocatechin gallateAryl hydrocarbon receptortarget
Epigallocatechin gallateDNA (cytosine-5)-methyltransferase 1target
Epigallocatechin gallateDihydrofolate reductase, mitochondrialtarget
EsculinGlutaminase kidney isoform, mitochondrialenzyme
EsculinAndrogen receptortarget
alpha-Tocopherol succinateSEC14-like protein 3target
alpha-Tocopherol succinateSEC14-like protein 2target
alpha-Tocopherol succinateNuclear receptor subfamily 1 group I member 2target
alpha-Tocopherol succinateProtein kinase C beta typetarget
alpha-Tocopherol succinateArachidonate 5-lipoxygenasetarget
alpha-Tocopherol succinateProtein kinase C alpha typetarget
alpha-Tocopherol succinateAlpha-tocopherol transfer proteincarrier
alpha-Tocopherol succinateGlutathione S-transferase A2enzyme
alpha-Tocopherol succinateGlutathione S-transferase Penzyme
alpha-Tocopherol succinateGlutathione S-transferase omega-1enzyme
alpha-Tocopherol succinateGlutathione S-transferase Mu 3enzyme
alpha-Tocopherol succinateGlutamate--cysteine ligase catalytic subunitenzyme
alpha-Tocopherol succinateNAD(P)H dehydrogenase [quinone] 1enzyme
alpha-Tocopherol succinateHeme oxygenase 1enzyme
alpha-Tocopherol succinateSuperoxide dismutase [Cu-Zn]enzyme
alpha-Tocopherol succinateLung epithelial cellstarget
alpha-Tocopherol succinateDiacylglycerol kinasetarget
D-alpha-Tocopherol acetateSEC14-like protein 3target
D-alpha-Tocopherol acetateSEC14-like protein 2target
D-alpha-Tocopherol acetateNuclear receptor subfamily 1 group I member 2target
D-alpha-Tocopherol acetateProtein kinase C beta typetarget
D-alpha-Tocopherol acetateArachidonate 5-lipoxygenasetarget
D-alpha-Tocopherol acetateProtein kinase C alpha typetarget
D-alpha-Tocopherol acetateAlpha-tocopherol transfer proteincarrier
D-alpha-Tocopherol acetateGlutathione S-transferase A2enzyme
D-alpha-Tocopherol acetateGlutathione S-transferase Penzyme
D-alpha-Tocopherol acetateGlutathione S-transferase omega-1enzyme
D-alpha-Tocopherol acetateGlutathione S-transferase Mu 3enzyme
D-alpha-Tocopherol acetateGlutamate--cysteine ligase catalytic subunitenzyme
D-alpha-Tocopherol acetateNAD(P)H dehydrogenase [quinone] 1enzyme
D-alpha-Tocopherol acetateHeme oxygenase 1enzyme
D-alpha-Tocopherol acetateSuperoxide dismutase [Cu-Zn]enzyme
alpha-Tocopherol acetateLeukotriene-B(4) omega-hydroxylase 1enzyme
alpha-Tocopherol acetateCytochrome P450 3A4enzyme
alpha-Tocopherol acetateFree radicalstarget
alpha-Tocopherol acetateAlpha-tocopherol transfer proteintransporter
alpha-Tocopherol acetateSEC14-like protein 4transporter
alpha-Tocopherol acetateSEC14-like protein 2transporter
alpha-Tocopherol acetateSEC14-like protein 3transporter
alpha-Tocopherol acetateApolipoprotein B receptortransporter
alpha-Tocopherol acetateScavenger receptor class B member 1transporter
alpha-Tocopherol acetateP-glycoprotein 1transporter
alpha-Tocopherol acetateVery low-density lipoprotein receptorcarrier
alpha-Tocopherol acetateLow-density lipoprotein receptorcarrier
OrmeloxifeneEstrogen receptor alphatarget
OrmeloxifeneEstrogen receptor betatarget
OrmeloxifeneSerum albumincarrier
Nanaomycin DActVA 6 proteintarget