Purinones
- Name
- Purinones
- Accession Number
- DBCAT000504
- Description
Not Available
- Drugs
Drug Drug Description Caffeine A stimulant present in tea, coffee, cola beverages, analgesic drugs, and agents used to increase alertness. It is also used in to prevent and treat pulmonary complications of premature birth. Valaciclovir An guanine nucleoside antiviral used to treat herpes exacerbations. Acyclovir A guanosine analog used to treat herpes simplex, varicella zoster, herpes zoster. Pentoxifylline A methylxanthine derivative used to treat intermittent claudication caused by chronic occlusive arterial disease of the limbs. Dimenhydrinate A medication used to prevent and treat nausea, vomiting, vertigo, and motion sickness. Ganciclovir A DNA polymerase inhibitor used to treat cytomegalovirus and herpetic keratitis of the eye. Penciclovir A topical nucleoside polymerase inhibitor used in the treatment of recurrent herpes labialis. Entecavir A nucleoside analogue used in the treatment of chronic hepatitis B for patients with active viral replication, histological evidence of active disease, or persistent elevations in liver transaminases. 8-azaguanine 8-azaguanine is one of the early purine analogs showing antineoplastic activity. It functions as an antimetabolite and is easily incorporated into ribonucleic acids. 7,9-Dimethylguanine Not Available 7-Deazaguanine Not Available 5'-S-methyl-5'-thioadenosine Not Available Guanine Not Available 9-Methylguanine Not Available Peldesine Peldesine is a potent inhibitor of human CCRF-CEM T-cell proliferation. It has undergone phase I trials for the treatment of Human Immunodeficiency Virus (HIV) infections. 7-cyano-7-deazaguanine Not Available 9-Deazahypoxanthine Not Available 9-Deazaguanine Not Available Besifovir dipivoxil Investigated for use/treatment in hepatitis (viral, B). Valomaciclovir Investigated for use/treatment in herpes zoster infections and viral infection. 6-O-benzylguanine 6-O-benzylguanine has been used in trials studying the treatment of HIV Infection, Adult Gliosarcoma, Adult Glioblastoma, Stage I Adult Hodgkin Lymphoma, and Stage II Adult Hodgkin Lymphoma, among others. Lobucavir Lobucavir has been used in trials studying the treatment of HIV Infections and Cytomegalovirus Infections. Queuine Current and on-going research suggests queuine is a natural biochemical compound that can be found endogenously in the human body and plays an essential role in the generation of other... Valomaciclovir stearate Valomaciclovir stearate is under investigation in clinical trial NCT00831103 (A Phase 2b Trial of EPB-348 for the Treatment of Herpes Zoster). Besifovir Not Annotated Theophylline A xanthine used to manage the symptoms of asthma, COPD, and other lung conditions caused by reversible airflow obstruction. Dyphylline A theophylline derivative used to treat asthma, bronchospasm, and COPD. Enprofylline Used in the management of symptoms of asthma. Also used in the treatment of peripheral vascular diseases and in the management of cerebrovascular insufficiency, sickle cell disease, and diabetic neuropathy. Aminophylline A bronchodilator consisting of theophylline that is used for the treatment of bronchospasm due to asthma, emphysema and chronic bronchitis. Oxtriphylline A bronchodilator used for the treatment of asthma, bronchitis, COPD, and emphysema. Theobromine theobromine is used as a vasodilator, a diuretic, and heart stimulant. And similar to caffeine, it may be useful in management of fatigue and orthostatic hypotension. Fenethylline Not Available Valganciclovir An antiviral medication used to treat cytomegalovirus (CMV) retinitis in patients diagnosed with acquired immunodeficiency syndrome (AIDS). 8-azaxanthine Not Available Xanthine A drug used to manage uncomplicated liver dysfunction in combination with orotic acid. Hypoxanthine Hypoxanthine is a purine and a reaction intermediate in the metabolism of adenosine and in the formation of nucleic acids by the salvage pathway. Naxifylline Investigated for use/treatment in congestive heart failure. Propentofylline Investigated for use/treatment in alzheimer's disease. 3-isobutyl-1-methyl-7H-xanthine Not Available Uric acid At present (August 2013), there is no approved indication for uric acid. The potential therapeutic use for uric acid is as an adjunct in acute ischemic stroke. Xanthinol A vasodilatory niacin found in diet supplements. Doxofylline A methylxanthine derivative used in chronic obstructive pulmonary disease, asthma, and bronchospasms. Lisofylline Lisofylline has been investigated for the treatment of Type 1 Diabetes Mellitus. Tonapofylline Tonapofylline has been used in trials studying the treatment of Heart Failure, Renal Insufficiency, and Congestive Heart Failure. Rolofylline Rolofylline is under clinical development by pharmaceutical company NovaCardia for the treatment of congestive heart failure. Reproterol A short-acting β2 adrenoreceptor agonist used to treat various types of asthma including allergic asthma, non-allergic asthma, and exercise-induced asthma. Cafedrine Cafedrine is under investigation in clinical trial NCT01311414 (Effect of Cafedrine/Theodrenaline and Urapidil on Cerebral Oxygenation). Theodrenaline Theodrenaline is under investigation in clinical trial NCT01311414 (Effect of Cafedrine/Theodrenaline and Urapidil on Cerebral Oxygenation). DPCPX CPX has been used in trials studying the treatment of Cystic Fibrosis. CT-2584 CT-2584 has been used in trials studying the treatment of Prostate Cancer. Ambroxol acefyllinate A bronchodilator indicated in the symptomatic treatment of bronchopulmonary disorders associated with bronchospasm. Bamifylline A methylxanthine derivative indicated in the treatment of bronchial asthma and other conditions with bronchospasm. Proxyphylline Not Annotated Acefylline Not Annotated Etamiphylline Not Annotated Pentifylline Not Annotated Bufylline Not Annotated Bromotheophylline Bromotheophylline is used as a diuretic and also, in combination with DB00316, it is used for the relief of temporary water weight gain, bloating, swelling and full feeling associated with... Furafylline Furafylline is a derivative of methylxanthine derivative. It was developed on the context of asthma as a long-acting alternative for theophylline. 8-chlorotheophylline When used in combination with DB01075 as the antiemetic DB00985, 8-chlorotheophylline is indicated for the prevention and treatment of nausea, vomiting, or vertigo of motion sickness. PCS-499 PCS-499 is under investigation in clinical trial NCT01487109 (A Phase 2 Study to Evaluate the Safety and Efficacy of CTP-499 in Type 2 Diabetic Nephropathy Patients). Lomifylline Not Annotated - Drugs & Drug Targets