Propylamines

Name
Propylamines
Accession Number
DBCAT000544
Description

Derivatives of propylamine (the structural formula NH2CH2CH2CH3).

Drugs
DrugDrug Description
CitalopramA selective serotonin reuptake inhibitor (SSRI) used in the treatment of depression.
AtomoxetineA selective norepinephrine reuptake inhibitor (SNRI) used in the management of Attention Deficit Hyperactivity Disorder (ADHD).
FluoxetineA selective serotonin reuptake inhibitor used to treat major depressive disorder, bulimia, OCD, premenstrual dysphoric disorder, panic disorder, and bipolar I.
TranylcypromineA monoamine oxidase inhibitor used to treat major depressive disorder.
PromethazineA first-generation antihistamine used for the treatment of allergic conditions, nausea and vomiting, and motion sickness.
EscitalopramA selective serotonin re-uptake inhibitor used in the treatment of major depressive disorder (MDD), generalized anxiety disorder (GAD), and other select psychiatric disorders such as obsessive-compulsive disorder (OCD).
ClorgilineAn antidepressive agent and monoamine oxidase inhibitor related to PARGYLINE.
MexiletineA class 1B antiarrhythmic agent used in the treatment of documented ventricular arrhythmias that warrant treatment.
NisoxetineNisoxetine is a selective norepinephrine reuptake inhibitor (SNRI) developed in the 1970s. It was originally investigated as an antidepressant but has no current clinical applications aside from being a research...
ThiazinamNot Annotated
Drugs & Drug Targets
DrugTargetType
CitalopramSodium-dependent serotonin transportertarget
CitalopramCytochrome P450 2C19enzyme
CitalopramCytochrome P450 2D6enzyme
CitalopramCytochrome P450 3A4enzyme
CitalopramP-glycoprotein 1transporter
CitalopramCytochrome P450 1A2enzyme
CitalopramHistamine H1 receptortarget
CitalopramAmine oxidase [flavin-containing] Aenzyme
CitalopramAmine oxidase [flavin-containing] Benzyme
CitalopramAldehyde oxidaseenzyme
AtomoxetineSodium-dependent noradrenaline transportertarget
AtomoxetineCytochrome P450 2D6enzyme
AtomoxetineSodium-dependent serotonin transportertarget
AtomoxetineCytochrome P450 2C19enzyme
AtomoxetineNMDA receptortarget
AtomoxetineSerum albumincarrier
Atomoxetinealpha1-acid glycoproteincarrier
AtomoxetineHigh affinity immunoglobulin gamma Fc receptor Icarrier
AtomoxetineG protein-activated inward rectifier potassium channel 1target
AtomoxetineKappa-type opioid receptortarget
FluoxetineSodium-dependent serotonin transportertarget
FluoxetineCytochrome P450 2C9enzyme
FluoxetineCytochrome P450 2D6enzyme
FluoxetineCYP2B proteinenzyme
FluoxetineCytochrome P450 1A2enzyme
FluoxetineCytochrome P450 3A4enzyme
FluoxetineCytochrome P450 2C19enzyme
FluoxetineP-glycoprotein 1transporter
FluoxetineCytochrome P450 2B6enzyme
FluoxetineCytochrome P450 3A5enzyme
FluoxetineSerum albumincarrier
FluoxetineAlpha-1-acid glycoprotein 1carrier
FluoxetinePotassium voltage-gated channel subfamily H member 2target
Fluoxetine5-hydroxytryptamine receptor 2Ctarget
FluoxetineCyclin-dependent kinases regulatory subunit 1target
FluoxetineNeuronal acetylcholine receptor subunit alpha-2target
FluoxetineNeuronal acetylcholine receptor subunit alpha-3target
FluoxetineNeuronal acetylcholine receptor subunit beta-4target
TranylcypromineAmine oxidase [flavin-containing] Btarget
TranylcypromineAmine oxidase [flavin-containing] Atarget
TranylcypromineCytochrome P450 2C19enzyme
TranylcypromineCytochrome P450 2A6enzyme
TranylcypromineCytochrome P450 2D6enzyme
TranylcypromineCytochrome P450 1A2enzyme
TranylcypromineCytochrome P450 2C9enzyme
TranylcypromineCytochrome P450 3A4enzyme
PromethazineDopamine D2 receptortarget
PromethazineHistamine H1 receptortarget
PromethazineMuscarinic acetylcholine receptor M4target
PromethazineMuscarinic acetylcholine receptor M1target
PromethazineMuscarinic acetylcholine receptor M5target
PromethazineMuscarinic acetylcholine receptor M2target
PromethazineMuscarinic acetylcholine receptor M3target
PromethazineCalmodulintarget
PromethazineCytochrome P450 2D6enzyme
PromethazineCytochrome P450 2B6enzyme
PromethazineP-glycoprotein 1transporter
PromethazineCytochrome P450 2C9enzyme
PromethazineHistamine H2 receptortarget
PromethazineAlpha adrenergic receptortarget
PromethazineP2 Purinoceptorstarget
PromethazineVoltage-gated sodium channel alpha subunittarget
PromethazineVoltage-gated Potassium Channelstarget
PromethazineCanalicular multispecific organic anion transporter 2transporter
PromethazineMultidrug resistance-associated protein 4transporter
PromethazineSerum albumincarrier
EscitalopramSodium-dependent serotonin transportertarget
EscitalopramCytochrome P450 3A4enzyme
EscitalopramCytochrome P450 2D6enzyme
EscitalopramSodium-dependent dopamine transportertarget
EscitalopramSodium-dependent noradrenaline transportertarget
EscitalopramMuscarinic acetylcholine receptor M1target
EscitalopramHistamine H1 receptortarget
EscitalopramCytochrome P450 2C19enzyme
EscitalopramP-glycoprotein 1transporter
Escitalopram5-hydroxytryptamine receptor 1Atarget
Escitalopram5-hydroxytryptamine receptor 2Atarget
Escitalopram5-hydroxytryptamine receptor 2Ctarget
EscitalopramAlpha-1 adrenergic receptorstarget
EscitalopramAlpha-2 adrenergic receptorstarget
EscitalopramDopamine D2 receptortarget
EscitalopramAmine oxidase [flavin-containing] Aenzyme
EscitalopramAmine oxidase [flavin-containing] Benzyme
EscitalopramAldehyde oxidaseenzyme
ClorgilineAmine oxidase [flavin-containing] Atarget
MexiletineSodium channel protein type 5 subunit alphatarget
MexiletineCytochrome P450 1A2enzyme
MexiletineCytochrome P450 2D6enzyme
MexiletineCytochrome P450 2B6enzyme
MexiletineCytochrome P450 2E1enzyme
MexiletineCytochrome P450 3A4enzyme
MexiletineAryl hydrocarbon receptortarget
NisoxetineSodium-dependent serotonin transportertarget