Deoxyribonucleosides
- Name
- Deoxyribonucleosides
- Accession Number
- DBCAT000597
- Description
A purine or pyrimidine base bonded to DEOXYRIBOSE.
- Drugs
Drug Drug Description Gemcitabine A nucleoside metabolic inhibitor used as adjunct therapy in the treatment of certain types of ovarian cancer, non-small cell lung carcinoma, metastatic breast cancer, and as a single agent for pancreatic cancer. Pentostatin An adenosine deaminase inhibitor used to treat hairy cell leukemia. Emtricitabine A nucleoside reverse transcriptase inhibitor used for the treatment and prophylaxis of HIV. Thymidine Thymidine is a pyrimidine deoxynucleoside. Thymidine is the DNA nucleoside T, which pairs with deoxyadenosine (A) in double-stranded DNA. In cell biology it is used to synchronize the cells in... Cladribine A purine antimetabolite used for the management of relapsing forms of Multiple Sclerosis (MS), used in patients who have not responded to or who were unable to tolerate alternative MS drugs. Idoxuridine A pyrimidine analog antiviral used for the treatment of viral eye infections, including herpes simplex keratitis. Floxuridine An antimetabolite used as palliative management for liver metastases of gastrointestinal malignancy. Trifluridine A nucleoside metabolic inhibitor used to treat keratoconjunctivitis and epithelial keratitis caused by simplex virus, and as a part of chemotherapy for certain types of metastatic gastrointestinal cancers. Zidovudine A dideoxynucleoside used in the treatment of HIV infection. Stavudine A dideoxynucleoside used in the treatment of HIV infection. Lamivudine A reverse transcriptase inhibitor used to treat HIV and hepatitis B infections. Didanosine A reverse transcriptase inhibitor used to treat HIV. Zalcitabine A dideoxynucleoside used to treat HIV. Abacavir An antiviral nucleoside reverse transcriptase inhibitor used in combination with other antiretrovirals for the treatment of HIV. Telbivudine A thymidine nucleoside analog used for the treatment of chronic hepatitis B with clinical evidence of viral replication or persistent elevations in serum aminotransferases (ALT or AST). 5'-S-methyl-5'-thioadenosine Not Available 8-hydroxy-2'-deoxyguanosine Not Available Brivudine A drug used to treat herpes zoster. Zidovudine monophosphate Not Available 5'-Fluoro-5'-Deoxyadenosine Not Available Zidovudine diphosphate Not Available Thymectacin Investigated for use/treatment in colorectal cancer. Alovudine Investigated for use/treatment in HIV infection. Elvucitabine Investigated for use/treatment in hepatitis (viral, B) and HIV infection. Tezacitabine Investigated for use/treatment in colorectal cancer, lung cancer, leukemia (unspecified), and gastric cancer. TAS-102 TAS-102 (Taiho Pharma USA, Inc.) is an anti-cancer drug under development and in stage 3 clinical trials for the treatment of colorectal cancer. It is composed of the thymidine phosphorylase... Broxuridine Broxuridine has been used in trials studying the treatment of Leukemia, Stage I Prostate Cancer, Stage IIB Prostate Cancer, and Stage IIA Prostate Cancer. Mericitabine Mericitabine has been investigated for the treatment of Hepatitis C, Chronic. Mericitabine is a polymerase inhibitor being developed for the treatment of chronic hepatitis C. Mericitabine is a prodrug of... Censavudine Censavudine has been used in trials studying the treatment of HIV-1 Infection. Cordycepin Cordycepin has been used in trials studying the treatment of Leukemia. Fozivudine Tidoxil Fozivudine Tidoxil has been used in trials studying the treatment of HIV Infections. Dexelvucitabine Dexelvucitabine has been used in trials studying the treatment of HIV Infections and Human Immunodeficiency Virus. Gemcitabine elaidate Gemcitabine elaidate has been used in trials studying the treatment of Solid Tumor, Lung Cancer, Non-small-cell Lung Cancer, and Metastatic Pancreatic Adenocarcinoma. Racivir Racivir, also known as RCV, is an oxothiolane nucleoside reverse transcriptase inhibitor similar to emtricitabine and lamivudine. Racivir is a 50:50 mixture of emtricitabine and its positive enantiomer. Racivir has... Apricitabine Apricitabine has been used in trials studying the treatment of HIV Infections. Raluridine Raluridine has been used in trials studying the treatment of HIV Infections. LY-2334737 LY2334737 has been used in trials studying the treatment of Solid Tumor, Metastatic Tumor, and Malignant Solid Tumor. Doxifluridine Doxifluridine has been investigated for the treatment of Stomach Cancer. 5-fluoro-2'-deoxycytidine 5-fluoro-2'-deoxycytidine has been used in trials studying the treatment of Neoplasms, Lung Neoplasms, Breast Neoplasms, Head and Neck Neoplasms, and Urinary Bladder Neoplasms, among others. Edoxudine A deoxythymidine analog used to treat herpetic keratitis. Ibacitabine Not Annotated 2'-C-methylcytidine A nucleoside analog with anti-hepatitis C virus (HCV) activity. Upon phosphorylation into its 5-triphosphate form, this metabolite inhibits viral RNA chain elongation and viral RNA-dependent RNA polymerase activity. This blocks... Lumicitabine Lumicitabine is under investigation in clinical trial NCT03010059 (A Study to Assess the Relative Bioavailability of JNJ64041575 Administered as 2 Different New Concept Formulations (Oral Suspension and Tablet) Compared to... Alovudine F-18 Alovudine F-18 is under investigation in clinical trial NCT02819024 (Dexamethasone Effects in Patients With Refractory Non-Small Cell Lung Cancer Using FLT Positron Emission Tomography). Islatravir Islatravir is under investigation in clinical trial NCT04233216 (Doravirine/islatravir (DOR/ISL) in Heavily Treatment-experienced (HTE) Participants for Human Immunodeficiency Virus Type 1 (HIV-1) Infection (MK-8591A-019)). Azvudine Azvudine is under investigation in clinical trial NCT04668235 (Study on Safety and Clinical Efficacy of AZVUDINE in COVID-19 Patients (Sars-cov-2 Infected)). Stavudine triphosphate Not Available Abacavir hydroxyacetate Prurisol is under investigation for the treatment of Chronic Stable Plaque Psoriasis. Prurisol has been investigated for the treatment of Plaque Psoriasis. Carbovir Not Annotated Dideoxyadenosine Not Annotated Navuridine Not Annotated North-methanocarbathymidine Not Annotated 2'-deoxythioguanosine Not Annotated - Drugs & Drug Targets