Prostaglandins F, Synthetic

Name
Prostaglandins F, Synthetic
Accession Number
DBCAT000676
Description

Analogs or derivatives of prostaglandins F that do not occur naturally in the body. They do not include the product of the chemical synthesis of hormonal PGF.

Drugs
DrugDrug Description
TravoprostA prostaglandin analog used in the treatment of elevated intraocular pressure due to open angle glaucoma or ocular hypertension.
Carboprost tromethamineA prostaglandin used to treat postpartum uterine hemorrhage due to atony when other methods of management have not been effective.
BimatoprostA prostaglandin analog used to treat hypotrichosis of the eyelashes and intraocular pressure in open angle glaucoma or ocular hypertension.
CloprostenolNot Annotated
LatanoprostAn isopropyl ester prodrug used to treat increased intraocular pressure.
ProstaleneAnalog of prostaglandin F2 alpha.
Drugs & Drug Targets
DrugTargetType
TravoprostProstaglandin F2-alpha receptortarget
Carboprost tromethamineProstaglandin E2 receptor EP1 subtypetarget
BimatoprostProstaglandin F2-alpha receptortarget
BimatoprostProstaglandin E2 receptor EP1 subtypetarget
BimatoprostProstaglandin E2 receptor EP3 subtypetarget
BimatoprostCytochrome P450 3A4enzyme
BimatoprostCytochrome P450 3A5enzyme
LatanoprostProstaglandin F2-alpha receptortarget
LatanoprostSolute carrier organic anion transporter family member 2A1transporter
LatanoprostSolute carrier family 22 member 6transporter
LatanoprostSolute carrier family 22 member 8transporter
LatanoprostCorneal esterasesenzyme