Organophosphonates
- Name
- Organophosphonates
- Accession Number
- DBCAT000698
- Description
Carbon-containing phosphonic acid compounds. Included under this heading are compounds that have carbon bound to either OXYGEN atom or the PHOSPHOROUS atom of the (P=O)O2 structure.
- Drugs
Drug Drug Description Pamidronic acid A bisphosphonate used to treat Paget's disease, to treat hypercalcemia of malignancy, and to treat osteolytic bone lesions. Zoledronic acid A bisphosphonate used to treat malignancy associated hypercalcemia, multiple myeloma, and bone metastasis from solid tumors. Alendronic acid A bisphosphonate drug that prevents osteoclastic bone resorption which is used for the prevention and treatment of osteoporosis. Ibandronate A bisphosphonate used to treat osteoporosis in postmenopausal women. Clodronic acid A bisphosphonate used to treat osteoporosis in postmenopausal women, hypercalcemia of malignancy, and osteolysis. Fosfomycin A broad spectrum antibiotic used to treat uncomplicated urinary tract infections. Risedronic acid A bisphosphonate used to treat osteoporosis and Paget's disease. Etidronic acid A bisphosphonate drug that prevents osteoclastic bone resorption; used for the prevention and treatment of osteoporosis. Tiludronic acid A bisphosphonate used for the treatment of Paget's disease of bone. Phosphonoacetic Acid A simple organophosphorus compound that inhibits DNA polymerase, especially in viruses and is used as an antiviral agent. [PubChem] Incadronic acid Incadronate has been investigated in the treatment of myeloma,[A14426,A14431] leukemia, and other cancers. It has also been investigated in patients with hypercalcemia of malignancy. Metrifonate Metrifonate or trichlorfon is an irreversible organophosphate acetylcholinesterase inhibitor. It is a prodrug which is activated non-enzymatically into 2,2-dichlorovinyl dimethyl phosphate. Tenofovir A nucleotide analog indicated in the treatment of HIV infections. Cidofovir An antiviral agent used to treat Cytomegalovirus (CMV) retinitis in patients with AIDS. Foscarnet An antiviral used to treat CMV, HIV, and HSV infections. Isoflurophate For use in the eye to treat certain types of glaucoma and other eye conditions, such as accommodative esotropia. Adenosine Phosphonoacetic Acid Not Available Fosmidomycin Not Available Sparfosic acid Sparfosic acid is a solid. This compound belongs to the n-acyl-alpha amino acids. These are compounds containing an alpha amino acid which bears an acyl group at the terminal nitrogen... Minodronic acid Investigated for use/treatment in multiple myeloma, breast cancer, osteoporosis, and lung cancer. Technetium Tc-99m medronate A diagnostic radiopharmaceutical agent used as a bone imaging agent to delineate areas of altered osteogenesis. Technetium Tc-99m oxidronate Technetium Tc-99m oxidronate is indicated in adult and pediatric patients to be used in skeletal imaging for diagnosis of areas that can present altered osteogenesis. When administered intravenously, it is... Tenofovir alafenamide A nucleoside analog reverse transcriptase inhibitor used for the treatment of chronic hepatitis B virus infection in adults with compensated liver disease. Technetium Tc-99m etidronate Not Annotated Neridronic Acid A bisphosphonate drug that prevents osteoclastic bone resorption which is used for the prevention and treatment of osteoporosis. Apomine Apomine has been used in trials studying the treatment of Osteoporosis and Unspecified Adult Solid Tumor, Protocol Specific. Oxidronic acid Oxidronic acid is a diagnostic skeletal imaging agent used to demonstrate areas of altered osteogenesis in adult and pediatric patients. - Drugs & Drug Targets