Phthalic Acids

Name
Phthalic Acids
Accession Number
DBCAT000723
Description

A group of compounds that has the general structure of a dicarboxylic acid-substituted benzene ring. The ortho-isomer is used in dye manufacture. (Dorland, 28th ed)

Drugs
DrugDrug Description
LenalidomideA thalidomide derivative used to treat multiple myeloma and anemia in low to intermediate risk myelodysplastic syndrome.
DibutylphthalateNot Annotated
PomalidomideA thalidomide analogue used in combination with dexamethasone to treat patients with multiple myeloma.
IberdomideIberdomide (CC-220) has been used in trials studying the treatment of Systemic Lupus Erythematosus.
CEP-9722CEP-9722 is under investigation in clinical trial NCT01345357 (Study of CEP-9722 in Combination With Gemcitabine and Cisplatin in Patients With Advanced Solid Tumors or Mantle Cell Lymphoma).
ButylidenephthalideNot Annotated
S-3APGS-3APG (S-3-[3-amino-phthalimido]-glutarimide) is a derivative of thalidomide with dual activity against B-cell neoplasias.
BioymifiBioymifi is a small molecule that acts as a tumor necrosis factor-related apoptosis-induced ligand (TRAIL) mimetic. Upon binding to the death receptor 5 (DR5) on cancer cells, bioymifi triggers apoptosis,...
TecovirimatAn antiviral medication used to treat smallpox, monkeypox, and cowpox.
Drugs & Drug Targets
DrugTargetType
LenalidomideProstaglandin G/H synthase 2target
LenalidomideTumor necrosis factor ligand superfamily member 11target
LenalidomideCadherin-5target
LenalidomideProtein cereblontarget
LenalidomideP-glycoprotein 1transporter
PomalidomideCytochrome P450 1A2enzyme
PomalidomideCytochrome P450 3A4enzyme
PomalidomideP-glycoprotein 1transporter
PomalidomideProtein cereblontarget
PomalidomideTumor necrosis factortarget
PomalidomideProstaglandin G/H synthase 2target
BioymifiTumor necrosis factor receptor superfamily member 10Btarget
TecovirimatEnvelope protein F13target
TecovirimatUDP-glucuronosyltransferase 1-1enzyme
TecovirimatUDP-glucuronosyltransferase 1-4enzyme
TecovirimatCytochrome P450 3A4enzyme
TecovirimatCytochrome P450 2C8enzyme
TecovirimatCytochrome P450 2C19enzyme
TecovirimatUDP-glucuronosyltransferase 1-3enzyme
TecovirimatATP-binding cassette sub-family G member 2transporter
TecovirimatCytochrome P450 2B6enzyme