Megestrol
- Name
- Megestrol
- Accession Number
- DBCAT000779
- Description
17-Hydroxy-6-methylpregna-3,6-diene-3,20-dione. A progestational hormone used most commonly as the acetate ester. As the acetate, it is more potent than progesterone both as a progestagen and as an ovulation inhibitor. It has also been used in the palliative treatment of breast cancer.
- ATC Classification
- Drugs
Drug Drug Description Megestrol acetate A progestin that is administered orally to treat anorexia and cachexia or serious unexplained weight loss and is also used as an antineoplastic agent to treat certain types of malignancy. - Drugs & Drug Targets
Drug Target Type Megestrol acetate Progesterone receptor target Megestrol acetate Glucocorticoid receptor target Megestrol acetate P-glycoprotein 1 transporter Megestrol acetate Cytochrome P450 3A4 enzyme