Neurokinin-1 Receptor Antagonists
- Name
- Neurokinin-1 Receptor Antagonists
- Accession Number
- DBCAT001050
- Description
Compounds that inhibit or block the activity of NEUROKININ-1 RECEPTORS.
- Drugs
Drug Drug Description Aprepitant A substance P/neurokinin 1 receptor antagonist used to treat nausea and vomiting caused by chemotherapy and surgery. Fosaprepitant An antiemetic drug used in combination with other antiemetic agents for the prevention of acute and delayed nausea and vomiting caused by chemotherapy. Casopitant Investigated for use/treatment in urinary incontinence and adverse effects (chemotherapy). Rolapitant A neurokinin-1 (NK-1) receptor antagonist used in combination with other antiemetics for the prevention of delayed nausea and vomiting associated with emetogenic chemotherapy. Vestipitant Vestipitant has been investigated for the treatment of Tinnitus. Vofopitant Vofopitant has been used in trials studying the treatment of PTSD, Primary Insomnia, and Sleep Initiation and Maintenance Disorders. Serlopitant Serlopitant has been investigated for the treatment of Prurigo Nodularis. RP-67580 Not Annotated - Drugs & Drug Targets