Hematoporphyrins

Name
Hematoporphyrins
Accession Number
DBCAT001083
Description

Iron-free derivatives of heme with 4 methyl groups, 2 hydroxyethyl groups and 2 propionic acid groups attached to the pyrrole rings. Some of these PHOTOSENSITIZING AGENTS are used in the PHOTOTHERAPY of malignant NEOPLASMS.

Drugs
DrugDrug Description
Porfimer sodiumA hematoporphyrin derivative used to treat esophageal cancer, endobronchial cancer, and high grade dysplasia in Barrett's Esophagus.
Dihematoporphyrin etherDihematoporphyrin ether is under investigation in clinical trial NCT00118222 (High Light and Low Light Dose PDT in Glioma).
Drugs & Drug Targets
DrugTargetType
Porfimer sodiumLow-density lipoprotein receptortarget
Porfimer sodiumHigh affinity immunoglobulin gamma Fc receptor Itarget