Hydroxamic Acids

All categories
Name
Hydroxamic Acids
Accession Number
DBCAT001106
Description

A class of weak acids with the general formula R-CONHOH.

Drugs
DrugDrug Description
DeferoxamineA chelating agent used to treat iron or aluminum toxicity and some blood transfusion dependent anemias.
VorinostatA histone deacetylase (HDAC) inhibitor used for the treatment of cutaneous manifestations in patients with progressive, persistent, or recurrent cutaneous T- cell lymphoma (CTCL) following prior systemic therapies.
4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamideNot Available
PanobinostatA non-selective histone deacetylase inhibitor used to treat multiple myeloma in combination with other antineoplastic agents.
BufexamacAn NSAID used to treat skin conditions like atopic eczema and inflammatory dermatoses.
GallichromeNot Available
Drugs & Drug Targets
DrugTargetType
DeferoxamineXanthine dehydrogenase/oxidaseenzyme
DeferoxamineIrontarget
DeferoxamineAluminumtarget
DeferoxamineAmyloid beta A4 proteintarget
VorinostatHistone deacetylase 1target
VorinostatHistone deacetylase 2target
VorinostatHistone deacetylase 3target
VorinostatHistone deacetylase 6target
VorinostatHistone deacetylase 8target
VorinostatAcetoin utilization proteintarget
VorinostatHistone deacetylasetarget
4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamideHistone deacetylase 8target
PanobinostatCytochrome P450 2D6enzyme
PanobinostatCytochrome P450 3A4enzyme
PanobinostatP-glycoprotein 1transporter
PanobinostatHistone deacetylasetarget
BufexamacProstaglandin G/H synthase 1target
BufexamacProstaglandin G/H synthase 2target
BufexamacHistone deacetylase 6target
BufexamacHistone deacetylase 10target
GallichromeIron(3+)-hydroxamate-binding protein FhuDtarget