Carbolines

Name
Carbolines
Accession Number
DBCAT001148
Description

A group of pyrido-indole compounds. Included are any points of fusion of pyridine with the five-membered ring of indole and any derivatives of these compounds. These are similar to CARBAZOLES which are benzo-indoles.

Drugs
DrugDrug Description
TadalafilA phosphodiesterase 5 inhibitor used to treat erectile dysfunction, benign prostatic hyperplasia, and pulmonary arterial hypertension.
HarmineNot Available
HarmalineNot Annotated
Drugs & Drug Targets
DrugTargetType
TadalafilcGMP-specific 3',5'-cyclic phosphodiesterasetarget
TadalafilCytochrome P450 3A4enzyme
TadalafilDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11Atarget
TadalafilRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gammatarget
HarmineAmine oxidase [flavin-containing] Atarget
HarmalineHistamine N-methyltransferasetarget