Organogold Compounds

Accession Number

DBCAT001223

Description

Organic compounds that contain GOLD as an integral part of the molecule. Some are used as ANTIRHEUMATIC AGENTS. The term chrysotherapy derives from an ancient Greek term for gold.

Drugs

Drug	Drug Description
Aurothioglucose	A gold compound used in the treatment of rheumatoid arthritis.
Sodium aurothiomalate	A disease-modifying antirheumatic drug (DMARD) indicated for the symptomatic treatment of arthritis.
Auranofin	An antirheumatic used to treat active, progressive, or destructive forms of inflammatory arthritis.

Drugs & Drug Targets

Drug	Target	Type
Aurothioglucose	Adenylate cyclase type 1	target
Aurothioglucose	Adenylate cyclase type 2	target
Aurothioglucose	Adenylate cyclase type 5	target
Sodium aurothiomalate	UDP-glucuronosyltransferase 1-1	enzyme
Auranofin	Inhibitor of nuclear factor kappa-B kinase subunit beta	target
Auranofin	Serum albumin	carrier
Auranofin	Peroxiredoxin-5, mitochondrial	target