Antisickling Agents

Name
Antisickling Agents
Accession Number
DBCAT001227
Description

Agents used to prevent or reverse the pathological events leading to sickling of erythrocytes in sickle cell conditions.

Drugs
DrugDrug Description
HydroxyureaAn antimetabolite used to treat sickle cell anemia crisis, resistant chronic myeloid leukemia, and Locally advanced squamous cell carcinomas of the head and neck (excluding the lip).
EfaproxiralNot Available
Methyl isocyanateMethyl isocyanate has been investigated for the treatment of Nosocomial Pneumonia.
CetiedilNot Annotated
Drugs & Drug Targets
DrugTargetType
HydroxyureaRibonucleoside-diphosphate reductase large subunittarget
HydroxyureaSolute carrier organic anion transporter family member 1A2transporter
HydroxyureaSolute carrier organic anion transporter family member 1B1transporter
HydroxyureaSolute carrier organic anion transporter family member 1B3transporter
HydroxyureaUrea transporter 2transporter
HydroxyureaUrea transporter 1transporter
HydroxyureaSolute carrier family 22 member 4transporter
HydroxyureaSolute carrier family 22 member 5transporter
HydroxyureaSerum albumincarrier
HydroxyureaUrease subunit alphaenzyme
EfaproxiralHemoglobin subunit alphatarget
EfaproxiralHemoglobin subunit betatarget