Adrenocorticotropic Hormone

Name
Adrenocorticotropic Hormone
Accession Number
DBCAT001331
Description

An anterior pituitary hormone that stimulates the ADRENAL CORTEX and its production of CORTICOSTEROIDS. ACTH is a 39-amino acid polypeptide of which the N-terminal 24-amino acid segment is identical in all species and contains the adrenocorticotrophic activity. Upon further tissue-specific processing, ACTH can yield ALPHA-MSH and corticotrophin-like intermediate lobe peptide (CLIP).

ATC Classification
Drugs
DrugDrug Description
TetracosactideA diagnostic agent used in the screening of patients presumed to have adrenocortical insufficiency.
CorticotropinA diagnostic agent used in the screening of patients presumed to have adrenocortical insufficiency.
Drugs & Drug Targets
DrugTargetType
TetracosactideAdrenocorticotropic hormone receptortarget
CorticotropinAdrenocorticotropic hormone receptortarget
CorticotropinCorticoliberintarget
Corticotropin3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2enzyme
Corticotropin25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrialenzyme
Corticotropin1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrialenzyme
CorticotropinCytochrome P450 3A4enzyme