Prostaglandin Antagonists

Name
Prostaglandin Antagonists
Accession Number
DBCAT001397
Description

Compounds that inhibit the action of prostaglandins.

Drugs
DrugDrug Description
Tiaprofenic acidA nonsteroidal anti-inflammatory (NSAID) used to manage inflammation and analgesia associated with rheumatoid arthritis and osteoarthritis.
SeratrodastSeratrodast (INN) is a thromboxane receptor antagonist used primarily in the treatment of asthma.
Tolfenamic acidIn the information for tolfenamic acid, it is stated that this drug, being an NSAID, is effective in treating the pain associated with the acute attack of migraines in adults.
LonazolacNot Annotated
Betulinic AcidBetulinic Acid has been used in trials studying the treatment of Dysplastic Nevus Syndrome.
BaicaleinBaicalein is under investigation in clinical trial NCT03830684 (A Randomized, Double-blind, Placebo-controlled, Multicenter and Phase ⅡA Clinical Trial for the Effectiveness and Safety of Baicalein Tablets in the Treatment of...
Drugs & Drug Targets
DrugTargetType
Tiaprofenic acidProstaglandin G/H synthase 2target
Tiaprofenic acidProstaglandin G/H synthase 1target
SeratrodastCytochrome P450 2C9enzyme
SeratrodastCytochrome P450 3A4enzyme
SeratrodastCytochrome P450 2C8enzyme
SeratrodastCytochrome P450 2C19enzyme
SeratrodastCytochrome P450 2B6enzyme
SeratrodastUDP-glucuronosyltransferase 1-9enzyme
SeratrodastProstaglandin G/H synthase 1enzyme
SeratrodastCytochrome P450 2A6enzyme
SeratrodastThromboxane A2 receptortarget
Tolfenamic acidProstaglandin G/H synthase 1target
Tolfenamic acidProstaglandin G/H synthase 2target
Tolfenamic acidCytochrome P450 3A4enzyme