Molecular Probes
- Name
- Molecular Probes
- Accession Number
- DBCAT001717
- Description
A group of atoms or molecules attached to other molecules or cellular structures and used in studying the properties of these molecules and structures. Radioactive DNA or RNA sequences are used in MOLECULAR GENETICS to detect the presence of a complementary sequence by NUCLEIC ACID HYBRIDIZATION.
- Drugs
Drug Drug Description Mipomersen An oligonucleotide drug used for the treatment of homozygous familial hypercholesterolemia. Bevasiranib Investigated for use/treatment in macular degeneration and diabetic retinopathy. Fomivirsen Indicated for the local treatment of cytomegalovirus (CMV) retinitis in patients with acquired immunodeficiency syndrome (AIDS), when other therapy has been ineffective or is considered unsuitable [FDA Label, L1428]. Patisiran A transthyretin-directed small interfering RNA used to treat polyneuropathy of hereditary transthyretin-mediated amyloidosis. Oblimersen Not Annotated Inotersen An antisense oligonucleotide used to treat polyneuropathy of hereditary transthyretin-mediated amyloidosis. Inclisiran A PCSK9-targeting short interfering RNA (siRNA) that lowers plasma LDL-cholesterol levels. Revusiran Revusiran is under investigation in clinical trial NCT02319005 (ENDEAVOUR: Phase 3 Multicenter Study of Revusiran (ALN-TTRSC) in Patients With Transthyretin (TTR) Mediated Familial Amyloidotic Cardiomyopathy (FAC)). Pafolacianine An optical imaging agent indicated in adult patients with ovarian cancer as an adjunct for intraoperative identification of malignant lesions. Golodirsen A drug used to treat certain mutations that cause Duchenne muscular dystrophy (DMD). - Drugs & Drug Targets