Uterotonic agents
- Name
- Uterotonic agents
- Accession Number
- DBCAT000218 (DBCAT002138)
- Description
Drugs that stimulate contraction of the myometrium. They are used to induce LABOR, OBSTETRIC at term, to prevent or control postpartum or postabortion hemorrhage, and to assess fetal status in high risk pregnancies. They may also be used alone or with other drugs to induce abortions (ABORTIFACIENTS). Oxytocics used clinically include the neurohypophyseal hormone OXYTOCIN and certain prostaglandins and ergot alkaloids. (From AMA Drug Evaluations, 1994, p1157)
- ATC Classification
- Drugs
Drug Drug Description Oxytocin A recombinant hormone used to induce or strengthen uterine contractions in pregnant women to aid in labor and delivery or to control postpartum bleeding. Carbetocin An oxytocin agent used to control postpartum hemorrhage and bleeding after giving birth. Carboprost tromethamine A prostaglandin used to treat postpartum uterine hemorrhage due to atony when other methods of management have not been effective. Dinoprostone A prostaglandin used to induce labor or abortion as well as to treat nonmetastatic gestational trophoblastic disease. Dinoprost tromethamine Used for aborting second-trimester pregnancy (between the twelfth to eighteenth week of gestation) and in incomplete abortion or for therapeutic abortion in cases of intrauterine fetal death and congenital abnormalities... Ergometrine An ergot alkaloid used for the treatment of postpartum haemorrhage and post abortion hemorrhage in patients with uterine atony. Methylergometrine An ergot alkaloid used to prevent and control uterine atony and hemorrhage before and after delivery. Ergotamine An alpha-1 selective adrenergic agonist vasoconstrictor used to treat migraines with or without aura and cluster headaches. Misoprostol A prostaglandin E1 analogue used to reduce the risk of NSAID-induced gastric ulcers and to terminate pregnancies. Dinoprost A medication used to induce a second trimester abortion. Demoxytocin Not Annotated Gemeprost A prostaglandin E1 analogue used for cervical dilation and, in combination with mifepristone, for pregnancy termination. Sulprostone A prostaglandin analogue used to treat post-partum hemorrhaging, induce medical abortion, and induce labour in instances of in utero fetal death. beta-Isosparteine Not Annotated - Drugs & Drug Targets