Amino Acids and Derivatives

All categories

Accession Number

DBCAT002151

Description

Not Available

ATC Classification

Drugs

Drug	Drug Description
Ademetionine	S-Adenosylmethionine (SAMe) is used as a drug in Europe for the treatment of depression, liver disorders, fibromyalgia, and osteoarthritis. It has also been introduced into the United States market as...
L-Glutamine	An amino acid commonly found as a component in total parenteral nutrition.
Levocarnitine	A quaternary ammonium compound used to treat carnitine deficiency or to stimulate gastric and pancreatic secretions in hyperlipoproteinemia.
Cysteamine	A cystine depleting agent used to treat the effects of cystinosis.
Betaine	A methyl group donor used for the treatment of homocystinuria to decrease elevated homocysteine blood levels.
Carglumic acid	An analog of N-acetylglutamate (NAG) used for the treatment of acute and chronic hyperammonemia in patients with N-acetylglutamate synthase (NAGS) deficiency.
Metreleptin	A leptin analogue used as an adjunct to diet as replacement therapy to treat the complications of leptin deficiency in patients various forms of lipodystrophy.

Drugs & Drug Targets

Drug	Target	Type
Ademetionine	Glycine N-methyltransferase	target
Ademetionine	S-adenosylmethionine decarboxylase proenzyme	target
Ademetionine	S-adenosylmethionine synthase isoform type-2	target
Ademetionine	Cystathionine beta-synthase	target
Ademetionine	S-adenosylmethionine synthase isoform type-1	target
Ademetionine	Cytochrome P450 2E1	enzyme
Ademetionine	Catechol O-methyltransferase	target
Ademetionine	Spermidine synthase	enzyme
Ademetionine	Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1	target
Ademetionine	Arsenite methyltransferase	target
L-Glutamine	CTP synthase 1	target
L-Glutamine	Amidophosphoribosyltransferase	target
L-Glutamine	Glutamine synthetase	target
L-Glutamine	Monocarboxylate transporter 10	transporter
L-Glutamine	Coagulation factor XIII A chain	enzyme
L-Glutamine	Glutaminase kidney isoform, mitochondrial	enzyme
L-Glutamine	Glutaminase liver isoform, mitochondrial	enzyme
L-Glutamine	Protein-glutamine gamma-glutamyltransferase 2	enzyme
L-Glutamine	Protein-glutamine gamma-glutamyltransferase 5	enzyme
L-Glutamine	Protein-glutamine gamma-glutamyltransferase 6	enzyme
L-Glutamine	Protein-glutamine gamma-glutamyltransferase K	enzyme
L-Glutamine	Protein-glutamine gamma-glutamyltransferase 4	enzyme
L-Glutamine	Protein-glutamine gamma-glutamyltransferase E	enzyme
L-Glutamine	Protein-glutamine gamma-glutamyltransferase Z	enzyme
L-Glutamine	Sodium-coupled neutral amino acid transporter 3	transporter
L-Glutamine	Neutral amino acid transporter B(0)	transporter
L-Glutamine	GMP synthase [glutamine-hydrolyzing]	enzyme
L-Glutamine	Asparagine synthetase [glutamine-hydrolyzing]	enzyme
L-Glutamine	Kynurenine--oxoglutarate transaminase 1	enzyme
L-Glutamine	Phosphoribosylformylglycinamidine synthase	enzyme
L-Glutamine	Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial	enzyme
L-Glutamine	Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 2	enzyme
L-Glutamine	CAD protein	enzyme
L-Glutamine	Glutamine--tRNA ligase	enzyme
L-Glutamine	Glutamine-dependent NAD(+) synthetase	enzyme
L-Glutamine	Large neutral amino acids transporter small subunit 2	transporter
L-Glutamine	Sodium-coupled neutral amino acid transporter 1	transporter
L-Glutamine	Sodium-coupled neutral amino acid transporter 2	transporter
L-Glutamine	Sodium- and chloride-dependent neutral and basic amino acid transporter B(0+)	transporter
L-Glutamine	Y+L amino acid transporter 1	transporter
L-Glutamine	Y+L amino acid transporter 2	transporter
L-Glutamine	Large neutral amino acids transporter small subunit 1	transporter
L-Glutamine	B(0,+)-type amino acid transporter 1	transporter
Levocarnitine	Carnitine O-palmitoyltransferase 1, liver isoform	target
Levocarnitine	Solute carrier family 22 member 4	target
Levocarnitine	Solute carrier family 22 member 5	target
Levocarnitine	Carnitine O-acetyltransferase	target
Levocarnitine	Mitochondrial carnitine/acylcarnitine carrier protein CACL	target
Levocarnitine	Mitochondrial carnitine/acylcarnitine carrier protein	target
Levocarnitine	Peroxisomal carnitine O-octanoyltransferase	target
Levocarnitine	Carnitine O-palmitoyltransferase 2, mitochondrial	target
Levocarnitine	Solute carrier family 22 member 4	transporter
Levocarnitine	Solute carrier organic anion transporter family member 1B1	transporter
Levocarnitine	Solute carrier family 22 member 5	transporter
Levocarnitine	Solute carrier family 22 member 16	transporter
Levocarnitine	Solute carrier family 22 member 8	transporter
Levocarnitine	Xanthine dehydrogenase/oxidase	target
Levocarnitine	Liver carboxylesterase 1	target
Levocarnitine	Myeloperoxidase	target
Cysteamine	Neuropeptide Y receptor type 2	target
Cysteamine	Cystine	target
Cysteamine	Myeloperoxidase	enzyme
Cysteamine	Serum albumin	carrier
Betaine	Cholinesterase	enzyme
Betaine	Proline dehydrogenase 1, mitochondrial	enzyme
Betaine	Sodium- and chloride-dependent betaine transporter	transporter
Betaine	Betaine--homocysteine S-methyltransferase 1	target
Carglumic acid	Carbamoyl-phosphate synthase [ammonia], mitochondrial	target
Metreleptin	Leptin receptor	target