Erythropoiesis-Stimulating Agents

Name
Erythropoiesis-Stimulating Agents
Accession Number
DBCAT002721
Description

Not Available

Drugs
DrugDrug Description
Darbepoetin alfaA recombinant form of human erythropoietin used to increase differentiation of progenitor cells to red blood cells in the treatment of anemia.
ErythropoietinA recombinant form of human erythropoietin used to increase differentiation of progenitor cells to red blood cells in the treatment of anemia.
Methoxy polyethylene glycol-epoetin betaA synthetic erythropoiesis stimulating agent (ESA) used to treat anemia associated with chronic kidney disease.
PeginesatidePeginesatide is used for the treatment of anemia due to chronic kidney disease (CKD) in adult patients on dialysis
VadadustatAn oral hypoxia-inducible factor prolyl-hydroxylase inhibitor used to treat symptomatic anemia associated with chronic kidney disease in adults on chronic maintenance dialysis.
Drugs & Drug Targets
DrugTargetType
Darbepoetin alfaErythropoietin receptortarget
ErythropoietinErythropoietin receptortarget
Methoxy polyethylene glycol-epoetin betaErythropoietin receptortarget
PeginesatideErythropoietin receptortarget
VadadustatEgl nine homolog 2target
VadadustatEgl nine homolog 3target
VadadustatEgl nine homolog 1target
VadadustatHypoxia-inducible factor 1-alphatarget
VadadustatEndothelial PAS domain-containing protein 1target
VadadustatUDP-glucuronosyltransferase 1-1enzyme
VadadustatUDP-glucuronosyltransferase 1-7enzyme
VadadustatUDP-glucuronosyltransferase 1-8enzyme
VadadustatUDP-glucuronosyltransferase 1-9enzyme
VadadustatUDP-glucuronosyltransferase 2B7enzyme
VadadustatCytochrome P450 2B6enzyme
VadadustatCytochrome P450 2C8enzyme
VadadustatCytochrome P450 3A4enzyme
VadadustatATP-binding cassette sub-family G member 2transporter
VadadustatSolute carrier family 22 member 8transporter
VadadustatSolute carrier family 22 member 6transporter
VadadustatSerum albumincarrier
VadadustatCytochrome P450 2C9enzyme