Cytochrome P-450 CYP2E1 Inhibitors (strong)

Name
Cytochrome P-450 CYP2E1 Inhibitors (strong)
Accession Number
DBCAT002630  (DBCAT002753)
Description

Not Available

Drugs
DrugDrug Description
MidostaurinAn antineoplastic agent used to treat high-risk acute myeloid leukemia (AML) with specific mutations, aggressive systemic mastocytosis (ASM), systemic mastocytosis with associated hematologic neoplasm (SM-AHN), or mast cell leukemia (MCL).
MiconazoleAn azole antifungal with broad-spectrum activity used to treat fungal infections affecting the vagina, mouth and skin, including candidiasis.
TioconazoleAn imidazole antifungal used to treat vulvovaginal candidiasis.
DiethylstilbestrolUsed in the treatment of prostate cancer. Previously used in the prevention of miscarriage or premature delivery in pregnant women prone to miscarriage or premature delivery.
Drugs & Drug Targets
DrugTargetType
MidostaurinProtein kinase C alpha typetarget
MidostaurinVascular endothelial growth factor receptor 2target
MidostaurinMast/stem cell growth factor receptor Kittarget
MidostaurinPlatelet-derived growth factor receptor alphatarget
MidostaurinPlatelet-derived growth factor receptor betatarget
MidostaurinReceptor-type tyrosine-protein kinase FLT3target
MidostaurinCytochrome P450 3A Subfamilyenzyme
MidostaurinCytochrome P450 1A2enzyme
MidostaurinCytochrome P450 2B6enzyme
MidostaurinCytochrome P450 2C8enzyme
MidostaurinCytochrome P450 2C9enzyme
MidostaurinCytochrome P450 2C19enzyme
MidostaurinCytochrome P450 2D6enzyme
MidostaurinCytochrome P450 2E1enzyme
MidostaurinCytochrome P450 3A4enzyme
MidostaurinCytochrome P450 3A5enzyme
MidostaurinCytochrome P450 3A7enzyme
MidostaurinCytochrome P450 3A43enzyme
MiconazoleCytochrome P450 2C9enzyme
MiconazoleCytochrome P450 2D6enzyme
MiconazoleCytochrome P450 3A4enzyme
MiconazoleP-glycoprotein 1transporter
MiconazoleCytochrome P450 51target
MiconazoleNitric oxide synthase, endothelialtarget
MiconazoleNitric oxide synthase, inducibletarget
MiconazoleCytochrome P450 11B1, mitochondrialenzyme
MiconazoleCytochrome P450 2A6enzyme
MiconazoleCytochrome P450 2B6enzyme
MiconazoleCytochrome P450 2C19enzyme
MiconazoleCytochrome P450 2E1enzyme
MiconazoleNuclear receptor subfamily 1 group I member 2target
MiconazoleLanosterol 14-alpha demethylaseenzyme
MiconazoleCytochrome P450 19A1enzyme
MiconazoleCalcium-activated potassium channeltarget
MiconazoleVoltage-gated Potassium Channelstarget
MiconazoleInward rectifier potassium channeltarget
MiconazoleVoltage gated L-type calcium channeltarget
MiconazoleSerum albumincarrier
MiconazoleCytochrome P450 2C8enzyme
TioconazoleLanosterol 14-alpha demethylasetarget
TioconazoleCytochrome P450 19A1enzyme
TioconazoleCytochrome P450 2C19enzyme
TioconazoleCytochrome P450 2E1enzyme
TioconazoleCytochrome P450 3A4enzyme
TioconazoleCytochrome P450 51target
DiethylstilbestrolEstrogen receptor alphatarget
DiethylstilbestrolEstrogen-related receptor gammatarget
DiethylstilbestrolTransthyretincarrier
DiethylstilbestrolCatechol O-methyltransferaseenzyme
DiethylstilbestrolCytochrome P450 19A1enzyme
DiethylstilbestrolATP-binding cassette sub-family G member 2transporter
DiethylstilbestrolP-glycoprotein 1transporter
DiethylstilbestrolEstrogen receptor betatarget
DiethylstilbestrolCytochrome P450 3A4enzyme
DiethylstilbestrolCytochrome P450 2C8enzyme
DiethylstilbestrolCytochrome P450 2C9enzyme
DiethylstilbestrolCytochrome P450 2E1enzyme
DiethylstilbestrolSteroid hormone receptor ERR1target
DiethylstilbestrolSteroid hormone receptor ERR2target
DiethylstilbestrolNuclear receptor coactivator 2target
DiethylstilbestrolNuclear receptor subfamily 1 group I member 2target
DiethylstilbestrolAndrogen receptortarget
DiethylstilbestrolSex hormone-binding globulintarget
DiethylstilbestrolSolute carrier organic anion transporter family member 1B1transporter
DiethylstilbestrolSolute carrier organic anion transporter family member 2B1transporter
DiethylstilbestrolBile salt export pumptransporter