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Search for "Aldosterone" returned 38 results

Showing 1-20 out of 38
DrugBank ID Name Formula Weight
DB04630
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Aldosterone C21H28O5 360.4440
... and collecting duct, aldosterone has two main actions: 1) aldosterone acts on mineralocorticoid receptors (MR) on principal cells in the distal tubule of the kidney nephron, increasing the ...
DB00700
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Eplerenone C24H30O6 414.4914
Aldosterone synthesis, which occurs primarily in the adrenal gland, is modulated by multiple factors, including angiotensin II and non-RAAS mediators such as adrenocorticotropic hormone (ACTH) and ...
DB00421
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Spironolactone C24H32O4S 416.5730
... the effect of aldosterone by competing for intracellular aldosterone receptor in the distal tubule cells. This increases the secretion of water and sodium, while decreasing the excretion of ...
DB01395
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Drospirenone C24H30O3 366.4932
... the estrogen-stimulated activity of the renin-angiotensin-aldosterone system, and is not androgenic. PA10729 97% 68873 12014580 DRSP Drospirenona [inn-spanish] Drospirenonum [inn-latin] 366 ...
DB00519
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Trandolapril C24H34N2O5 430.5372
Decreased aldosterone secretion leads to diuresis, natriuresis, and a small increase of serum potassium. Tarka (Trandolapril + Verapamil hydrochloride) Trandolapril Trandolapril is the ethyl ester ...
DB01342
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Forasartan C23H28N8 416.5220
... which also stimulates the synthesis and release of aldosterone, blockage of its effects results in a decreases in systemic vascular resistance. Forasartan Forasartan, a specific angiotensin II ...
DB00796
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Candesartan C24H20N6O3 440.4540
... which also stimulates the synthesis and release of aldosterone, blockage of its effects results in a decreases in systemic vascular resistance. Tablet Oral 02239091 DB00796 Approximately 9 hours.
DB00966
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Telmisartan C33H30N4O2 514.6169
Telmisartan works by blocking the vasoconstrictor and aldosterone secretory effects of angiotensin II. PA451605 Highly bound to plasma proteins (>99.5%), mainly albumin and a1-acid glycoprotein.
DB01180
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Rescinnamine C35H42N2O9 634.7160
Angiotensin II also stimulates aldosterone secretion by the adrenal cortex. PA451235 32681 8770 APRD00112 Methyl Trimethoxycinnamoylreserpate Recinnamine Rescinnamin Reserpinene Reserpinin ...
DB00492
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Fosinopril C30H46NO7P 563.6625
Angiotensin II also stimulates aldosterone secretion by the adrenal cortex. PA449710 87% 55891 194429 APRD00526 Fosinopril Sodium Human overdoses of fosinopril have not been reported, but the most ...
DB00584
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Enalapril C20H28N2O5 376.4467
Angiotensin II also stimulates aldosterone secretion by the adrenal cortex. PA449456 20.1 to 89.1% 5362032 191211 APRD00510 Enalapril Maleate Enalaprila [INN-Spanish] Enalaprilat Enalaprilum [INN ...
DB00678
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Losartan C22H23ClN6O 422.9110
... which also stimulates the synthesis and release of aldosterone, blockage of its effects results in decreases in systemic vascular resistance. Neither Losartan or its metabolite inhibit the ...
DB00542
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Benazepril C24H28N2O5 424.4895
... which leads to decreased vasopressor activity and to decreased aldosterone secretion. Benazeprilat may also act on kininase II, an enzyme identical to ACE that degrades the vasodilator bradykinin.
DB01347
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Saprisartan C25H22BrF3N4O4S 611.4310
Saprisartan blocks the renin-angiotensin-aldosterone system (RAAS) at the level of the AT1 receptor that mediates most, if not all, of the important actions of Ang II. Saprisartan binds ...
DB01349
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Tasosartan C23H21N7O 411.4591
Tasosartan blocks the renin-angiotensin-aldosterone system (RAAS) at the level of the AT1 receptor that mediates most, if not all, of the important actions of Ang II. Tasosartan binds reversibly ...
DB00866
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Alprenolol C15H23NO2 249.3486
... the production of renin, thereby inhibiting angiotensin II and aldosterone production and therefore inhibits the vasoconstriction and water retention due to angiotensin II and aldosterone ...
DB00594
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Amiloride C6H8ClN7O 229.6270
Amiloride is not an aldosterone antagonist and its effects are seen even in the absence of aldosterone. Alti-Amiloride HCTZ (Amiloride Hcl + Hydrochlorothiazide) Ami-Hydro Tab (Amiloride Hcl ...
DB00790
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Perindopril C19H32N2O5 368.4678
... vasoconstriction, increased plasma renin activity and decreased aldosterone secretion. The latter results in diuresis and natriuresis and may be associated with a small increase of serum ...
DB00960
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Pindolol C14H20N2O2 248.3208
... the production of renin, thereby inhibiting angiotensin II and aldosterone production and therefore inhibits the vasoconstriction and water retention due to angiotensin II and aldosterone ...
DB01203
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Nadolol C17H27NO4 309.4006
... the production of renin, thereby inhibiting angiotensin II and aldosterone production. Nadolol therefore inhibits the vasoconstriction and water retention due to angiotensin II and aldosterone ...
Showing 1-20 out of 38

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