| DrugBank ID |
Name |
Formula |
Weight |
DB01394
|
Colchicine |
C22H25NO6 |
399.4370 |
| ... Phosphoric Acid + Phosphorus + Uranium Nitrate) Colchicine Colchicine is a highly poisonous alkaloid, originally extracted from plants of the genus Colchicum (Autumn crocus, also known as the ... |
DB01032
|
Probenecid |
C13H19NO4S |
285.3590 |
| ... renal tubular blocking agent and is used in combination with colchicine to treat chronic gouty arthritis when complicated by frequent, recurrent acute attacks of gout. It inhibits the tubular ... |
DB00518
|
Albendazole |
C12H15N3O2S |
265.3310 |
| ... the tegument and intestinal cells of the worm by binding to the colchicine-sensitive site of tubulin, thus inhibiting its polymerization or assembly into microtubules. The loss of the ... |
DB00643
|
Mebendazole |
C16H13N3O3 |
295.2927 |
| ... the tegument and intestinal cells of the worm by binding to the colchicine-sensitive site of tubulin, thus inhibiting its polymerization or assembly into microtubules. The loss of the ... |
DB00175
|
Pravastatin |
C23H36O7 |
424.5277 |
| Bezafibrate Increased risk of myopathy/rhabdomyolysis
Colchicine Increased risk of rhabdomyolysis with this combination
Cyclosporine Possible myopathy and rhabdomyolysis
Fenofibrate Increased risk ... |
DB01095
|
Fluvastatin |
C24H26FNO4 |
411.4659 |
| ... Cholestyramine Increased/decreased effect according to spacing
Colchicine Increased risk of rhabdomyolysis with this combination
Colestipol Increased/decreased effect according to spacing ... |
DB01229
|
Paclitaxel |
C47H51NO14 |
853.9061 |
| Whereas drugs like colchicine cause the depolymerization of microtubules in vivo, paclitaxel arrests their function by having the opposite effect; it hyper-stabilizes their structure. This ... |
DB01248
|
Docetaxel |
C43H53NO14 |
807.8792 |
| Whereas drugs like colchicine cause the depolymerization of microtubules in vivo, docetaxel arrests their function by having the opposite effect; it hyper-stabilizes their structure. This destroys ... |
DB00439
|
Cerivastatin |
C26H34FNO5 |
459.5503 |
| ... The macrolide possibly increases the statin toxicity
Colchicine Increased risk of rhabdomyolysis with this combination
Cyclosporine Possible myopathy and rhabdomyolysis
Diltiazem Diltiazem ... |
DB01211
|
Clarithromycin |
C38H69NO13 |
747.9534 |
| ... Possible serotoninergic syndrome with this combination
Colchicine Severe colchicine toxicity can occur
Cyclosporine The macrolide increases the effect of cyclosporine
Darifenacin This potent ... |
DB00727
|
Nitroglycerin |
C3H5N3O9 |
227.0865 |
| ... zinc)
Aribosan B31 - liq (apis mellifica + barberry root + colchicine + convallaria majalis + nitroglycerin + poison oak + potassium iodide + quinine dihyrochloride)
CRC-plex (arnica montana ... |
DB00227
|
Lovastatin |
C24H36O5 |
404.5396 |
| ... The macrolide possibly increases the statin toxicity
Colchicine Increased risk of rhabdomyolysis with this combination
Cyclosporine Possible myopathy and rhabdomyolysis
Danazol Risk of severe ... |
DB01076
|
Atorvastatin |
C33H35FN2O5 |
558.6398 |
| ... The macrolide possibly increases the statin toxicity
Colchicine Increased risk of rhadbomyolysis with this combination
Cyclosporine Possible myopathy and rhabdomyolysis
Delavirdine The NNRT ... |
DB00199
|
Erythromycin |
C37H67NO13 |
733.9268 |
| ... increases the effect of clozapine
Colchicine Severe colchicine toxicity can occur
Cyclosporine The macrolide increases the effect of cyclosporine
Diazepam The macrolide increases the effect of ... |
DB00661
|
Verapamil |
C27H38N2O4 |
454.6016 |
| Monitor for changes in the therapeutic/adverse effects of Colchicine if Verapamil is initiated, discontinued or dose changed.
Conivaptan Conivaptan, a strong CYP3A4 inhibitor, may increase the ... |
DB00976
|
Telithromycin |
C43H65N5O10 |
812.0037 |
| ... can occur
Colchicine Telithromycin may reduce clearance of Colchicine. Consider alternate therapy or monitor for changes in the therapeutic/adverse effects of Colchicine if Telithromycin is ... |
DB00091
|
Cyclosporine |
C62H111N11O12 |
1202.6112 |
| ... Clindamycin Clindamycin decreases the effect of cyclosporine
Colchicine Increased toxicity of both drugs
Danazol The androgen increases the effect and toxicity of cyclosporine
Diclofenac ... |