| DrugBank ID |
Name |
Formula |
Weight |
DB00625
|
Efavirenz |
C14H9ClF3NO2 |
315.6750 |
| Efavirenz Efavirenz (dideoxyinosine, ddI) is an oral nucleoside reverse transcriptase inhibitor (NRTI). It is a synthetic purine derivative and, similar to zidovudine, zalcitabine, and stavudine. |
DB00300
|
Tenofovir |
C9H14N5O4P |
287.2123 |
| Atripla (tenofovir + emtricitabine + efavirenz)
Truvada (tenofovir + emtricitabine) Tenofovir Tenofovir belongs to a class of antiretroviral drugs known as nucleotide analogue reverse ... |
DB00247
|
Methysergide |
C21H27N3O2 |
353.4580 |
| ... antiretroviral agent may increase the ergot derivative toxicity
Efavirenz The antiretroviral agent may increase the ergot derivative toxicity
Eletriptan Possible severe and prolonged ... |
DB00404
|
Alprazolam |
C17H13ClN4 |
308.7650 |
| ... benzodiazepine
Digoxin The benzodiazepine increases the effect
Efavirenz The antiviral agent increases the effect and toxicity of benzodiazepine
Erythromycin The macrolide increases the effect ... |
DB00637
|
Astemizole |
C28H31FN4O |
458.5703 |
| ... Delavirdine Increased risk of cardiotoxicity and arrhythmias
Efavirenz Increased risk of cardiotoxicity and arrhythmias
Erythromycin Increased risk of cardiotoxicity and arrhythmias
Fluoxetine ... |
DB00224
|
Indinavir |
C36H47N5O4 |
613.7895 |
| ... the effect and toxicity of the ergot derivative
Efavirenz Efavirenz decreases the effect of indinavir
Ergotamine Increases the effect and toxicity of the ergot derivative
Erlotinib This CYP3A4 ... |
DB01211
|
Clarithromycin |
C38H69NO13 |
747.9534 |
| ... Increases the effect and toxicity of theophylline
Efavirenz Efavirenz decreases levels of clarithromycin
Eletriptan This macrolide increases the effect and toxicity of eletriptan
Eplerenone ... |
DB01072
|
Atazanavir |
C38H52N6O7 |
704.8555 |
| ... Increases the effect and toxicity of tricyclics
Efavirenz Efavirenz decreases the levels/effects of atazanavir
Ergotamine Increases the effect and toxicity of ergot derivative
Erlotinib This ... |
DB00897
|
Triazolam |
C17H12Cl2N4 |
343.2100 |
| ... blocker increases the effect and toxicity of the benzodiazepine
Efavirenz The antiviral agent increases the effect and toxicity of benzodiazepine
Erythromycin The macrolide increases the ... |
DB06287
|
Temsirolimus |
C56H87NO16 |
1030.2871 |
| Concomitant therapy should be avoided.
Efavirenz Efavirenz may increase the metabolism of Temsirolimus decreasing its efficacy. Concomitant therapy should be avoided.
Fluorouracil Co ... |
DB00227
|
Lovastatin |
C24H36O5 |
404.5396 |
| ... Diltiazem increases the effect and toxicity of the statin
Efavirenz The NNRT inhibitor increases the effect and toxicity of the statin
Erythromycin The macrolide possibly increases the statin ... |
DB00333
|
Methadone |
C21H27NO |
309.4452 |
| ... barbiturate The barbiturate decreases the effect of methadone
Efavirenz The antiretroviral agent decreases the effect of methadone
Ethotoin The hydantoin decreases the effect of methadone ... |
DB00683
|
Midazolam |
C18H13ClFN3 |
325.7670 |
| ... The agent increases the serum levels and toxicity of docetaxel
Efavirenz The antiviral agent increases the effect and toxicity of benzodiazepine
Erythromycin The macrolide increases the effect ... |
DB01076
|
Atorvastatin |
C33H35FN2O5 |
558.6398 |
| ... Diltiazem increases the effect and toxicity of atorvastatin
Efavirenz The NNRT inhibitor increases the effect and toxicity of the statin
Erythromycin The macrolide possibly increases the ... |
DB00320
|
Dihydroergotamine |
C33H37N5O5 |
583.6774 |
| ... The antiretroviral agent may increase the ergot derivative
Efavirenz The antiretroviral agent may increase the ergot derivative
Eletriptan Possible severe and prolonged vasoconstriction ... |
DB00696
|
Ergotamine |
C33H35N5O5 |
581.6615 |
| ... antiretroviral agent may increase the ergot derivative toxicity
Efavirenz The antiretroviral agent may increase the ergot derivative toxicity
Eletriptan Possible severe and prolonged ... |
DB00091
|
Cyclosporine |
C62H111N11O12 |
1202.6112 |
| ... Diltiazem increases the effect and toxicity of cyclosporine
Efavirenz Efavirenz decreases the levels of cyclosporine
Erythromycin The macrolide increases the effect of cyclosporine
Ethinyl ... |
DB01036
|
Tolterodine |
C22H31NO |
325.4876 |
| Adjust Tolterodine dose and monitor for efficacy and toxicity.
Efavirenz Efavirenz may decrease the metabolism and clearance of Tolterodine. Adjust Tolterodine dose and monitor for efficacy and ... |
DB00342
|
Terfenadine |
C32H41NO2 |
471.6734 |
| ... Doxepin Increased risk of cardiotoxicity and arrhythmias
Efavirenz Increased risk of cardiotoxicity and arrhythmias
Erythromycin Increased risk of cardiotoxicity and arrhythmias
Flecainide ... |
DB00604
|
Cisapride |
C23H29ClFN3O4 |
465.9450 |
| ... Doxepin Increased risk of cardiotoxicity and arrhythmias
Efavirenz Increased risk of cardiotoxicity and arrhythmias
Encainide Increased risk of cardiotoxicity and arrhythmias
Erythromycin ... |