Search Results
Search for "Estrogen" returned 62 results
Showing 1-20 out of 62
| DrugBank ID | Name | Formula | Weight |
|---|---|---|---|
DB00286
|
Conjugated Estrogens | C18H21NaO5S | 372.4110 |
| ... estrogens + medroxyprogesteron) Conjugated Estrogens Conjugated estrogens, a mixture of the water soluble salts of sulfate esters from estrone, equilin, 17 α-dihydroequilin, and other ... | |||
| DB00783
|
Estradiol | C18H24O2 | 272.3820 |
| ... estrogen) and exhibits little estrogenic activity in estrogen-responsive tissues. Various isomers can be synthesized. [PubChem] Disc Transdermal Gel Transdermal Liquid Intramuscular Patch ... | |||
| DB00269
|
Chlorotrianisene | C23H21ClO3 | 380.8640 |
| The estrogen-stimulated endometrium may bleed within 48-72 hours after discontinuance of estrogen therapy. Paradoxically, prolonged estrogen therapy may cause shrinkage of the endometrium and an ... | |||
| DB00655
|
Estrone | C18H22O2 | 270.3661 |
| ... obtained from pregnant equine urine, is the primary circulating estrogen after menopause. Estrone is naturally derived from the peripheral conversion of androstenedione by an aromatase enzyme ... | |||
| DB00977
|
Ethinyl Estradiol | C20H24O2 | 296.4034 |
| It is one of two estrogens currently used in oral contraceptive pills. The other, mestranol, is converted to ethinyl estradiol before it is biologically active. Ethinyl estradiol and norethindrone ... | |||
| DB00481
|
Raloxifene | C28H27NO4S | 473.5830 |
| Raloxifene Raloxifene, a selective estrogen receptor modulator (SERM) of the benzothiophene class, is similar to tamoxifen in that it produces estrogen-like effects on bone and lipid metabolism ... | |||
| DB00539
|
Toremifene | C26H28ClNO | 405.9600 |
| Toremifene binds to estrogen receptors and may exert estrogenic, antiestrogenic, or both activities, depending upon the duration of treatment, animal species, gender, target organ, or endpoint ... | |||
| DB00882
|
Clomifene | C26H28ClNO | 405.9600 |
| ... binding sites and may delay replenishment of intracellular estrogen receptors. Clomifene initiates a series of endocrine events culminating in a preovulatory gonadotropin surge and subsequent ... | |||
| DB00890
|
Dienestrol | C18H18O2 | 266.3343 |
| It is an estrogen receptor agonist. Estrogens work partly by increasing a normal clear discharge from the vagina and making the vulva and urethra healthy. Using or applying an estrogen relieves or ... | |||
| DB00255
|
Diethylstilbestrol | C18H20O2 | 268.3502 |
| ... estrogen that was developed to supplement a woman's natural estrogen production. In 1971, the Food and Drug Administration (FDA) issued a Drug Bulletin advising physicians to stop prescribing ... | |||
| DB00675
|
Tamoxifen | C26H29NO | 371.5146 |
| ... selective estrogen receptor modulators (SERMs), which have both estrogenic and antiestrogenic effects. Tamoxifen has the same nucleus as diethylstilbestrol but possesses an additional side ... | |||
| DB00947
|
Fulvestrant | C32H47F5O3S | 606.7710 |
| It is an estrogen receptor antagonist with no agonist effects, which works both by down-regulating and by degrading the estrogen receptor. Solution Intramuscular 02248624 DB00947 40 days ... | |||
| DB01006
|
Letrozole | C17H11N5 | 285.3027 |
| ... interfering with the estrogen receptor, rather than inhibiting estrogen production. Letrozole is approved by the United States Food and Drug Administration (FDA) for the treatment of local or ... | |||
| DB04575
|
Quinestrol | C25H32O2 | 364.5204 |
| Estrogens increase the hepatic synthesis of sex hormone binding globulin (SHBG), thyroid-binding globulin (TBG), and other serum proteins and suppress follicle-stimulating hormone (FSH) from the ... | |||
| DB01406
|
Danazol | C22H27NO2 | 337.4553 |
| ... stimulation as a result of decreased ovarian production of estrogen. A direct effect on steroid receptor sites in breast tissue also is possible. Disappearance of nodularity, relief of pain ... | |||
| DB01217
|
Anastrozole | C17H19N5 | 293.3663 |
| ... levels by ovariectomy premenopausally and by use of anti-estrogens and progestational agents both pre- and post-menopausally, and these interventions lead to decreased tumor mass or delayed ... | |||
| DB01357
|
Mestranol | C21H26O2 | 310.4299 |
| It binds to (and activates) the estrogen receptor. Mestranol is a biologically inactive prodrug of ethinylestradiol to which it is demethylated in the liver with a conversion efficiency of 70%. | |||
| DB00990
|
Exemestane | C20H24O2 | 296.4034 |
| While the main source of estrogen (primarily estradiol) is the ovary in premenopausal women, the principal source of circulating estrogens in postmenopausal women is from conversion of adrenal and ... | |||
| DB04573
|
Estriol | C18H24O3 | 288.3814 |
| Estriol Estriol (also oestriol) is one of the three main estrogens produced by the human body. It is only produced in significant amounts during pregnancy as it is made by the placenta. In ... | |||
| DB00357
|
Aminoglutethimide | C13H16N2O2 | 232.2783 |
| ... the production of adrenal glucocorticoids, mineralocorticoids, estrogens, and androgens. PA448375 21-25% 2145 9819 APRD00592 Dl-Aminoglutethimide P-Aminoglutethimide Oral LD50s (mg/kg): rats ... | |||
Showing 1-20 out of 62