| DrugBank ID |
Name |
Formula |
Weight |
DB00196
|
Fluconazole |
C13H12F2N6O |
306.2708 |
| Fluconazole Fluconazole, a synthetic antifungal agent of the imidazole class, is used to treat vaginal candidiasis. PA449653 11 to 12% 3365 192927 APRD00327 Symptoms of overdose include ... |
DB01263
|
Posaconazole |
C37H42F2N8O4 |
700.7774 |
| ... oropharyngeal candidiasis refractory to itraconazole and/or fluconazole. 4-[4-[4-[4-[[(5R)-5-(2,4-difluorophenyl)-5-(1,2,4-triazol-1-ylmethyl)oxolan-3-yl]methoxy]phenyl]piperazin-1-yl]phenyl ... |
DB01153
|
Sertaconazole |
C20H15Cl3N2OS |
437.7700 |
| ... and may be partly responsible for the fungistatic activity of fluconazole. Mammalian cell demethylation is much less sensitive to fluconazole inhibition. Sertaconazole exhibits <i>in vitro</i ... |
DB01167
|
Itraconazole |
C35H38Cl2N8O4 |
705.6330 |
| Mammalian cell demethylation is much less sensitive to fluconazole inhibition. Itraconazole exhibits <i>in vitro</i> activity against <i>Cryptococcus neoformans</i> and <i>Candida spp.</i ... |
DB01110
|
Miconazole |
C18H14Cl4N2O |
416.1290 |
| Miconazole Miconazole is an anti-fungal medication related to fluconazole (Diflucan), ketoconazole (Nizoral), itraconazole (Sporanox), and clotrimazole (Lotrimin, Mycelex). It is used either on ... |
DB01127
|
Econazole |
C18H15Cl3N2O |
381.6840 |
| Econazole Econazole is an antifungal medication related to fluconazole (Diflucan), ketoconazole (Nizoral), itraconazole (Sporanox), and clotrimazole (Lotrimin, Mycelex). Econazole prevents fungal ... |
DB01095
|
Fluvastatin |
C24H26FNO4 |
411.4659 |
| ... effect
Fenofibrate Increased risk of myopathy/rhabdomyolysis
Fluconazole Fluconazole increases the effect and toxicity of fluvastatin
Gemfibrozil Increased risk of myopathy/rhabdomyolysis ... |
DB01026
|
Ketoconazole |
C26H28Cl2N4O4 |
531.4310 |
| Ketoconazole Ketoconazole, like clotrimazole, fluconazole, itraconazole, and miconazole, is an imidazole antifungal agent. PA450146 99% (in vitro, plasma protein binding) 47576 186839 APRD00401 2 ... |
DB00482
|
Celecoxib |
C17H14F3N3O2S |
381.3720 |
| ... effect
Dicumarol Increases the anticoagulant effect
Fluconazole Fluconazole increases the effect of celecoxib
Lithium The COX-2 inhibitor increases serum levels of lithium
Rifampin Decreased ... |
DB00531
|
Cyclophosphamide |
C7H15Cl2N2O2P |
261.0860 |
| ... antineoplasic agent decreases the effect of digoxin
Fluconazole Fluconazole reduces metabolism and clearance of cyclophosphamide
Pentostatin Increased toxicity of cyclophosphamide ... |
DB01166
|
Cilostazol |
C20H27N5O2 |
369.4607 |
| ... Erythromycin Erythromycin increases the effect of cilostazol
Fluconazole Fluconazole decreases the effect of cilostazol
Fluoxetine Fluoxetine increases the effect of cilostazol
Fluvoxamine ... |
DB00690
|
Flurazepam |
C21H23ClFN3O |
387.8780 |
| ... increased levels of the hydantoin, decrease of benzodiazepine
Fluconazole Fluconazole increases the effect of the benzodiazepine
Fosamprenavir Amprenavir increases the effect and toxicity of ... |
DB01068
|
Clonazepam |
C15H10ClN3O3 |
315.7110 |
| ... benzodiazepine
Clozapine Increased risk of toxicity
Fluconazole Fluconazole increases the effect of the benzodiazepine
Indinavir The protease inhibitor increases the effect of the ... |
DB00475
|
Chlordiazepoxide |
C16H14ClN3O |
299.7550 |
| ... levels of the hydantoin, decrease of benzodiazepine
Fluconazole Fluconazole increases the effect of the benzodiazepine
Fosphenytoin Possible increased levels of the hydantoin, decrease of ... |
DB00628
|
Clorazepate |
C16H11ClN2O3 |
314.7230 |
| ... increased levels of the hydantoin, decrease of benzodiazepine
Fluconazole Fluconazole increases the effect of the benzodiazepine
Fosamprenavir Amprenavir increases the effect and toxicity of ... |
DB01215
|
Estazolam |
C16H11ClN4 |
294.7380 |
| ... increased levels of the hydantoin, decrease of benzodiazepine
Fluconazole Fluconazole increases the effect of the benzodiazepine
Fosphenytoin Possible increased levels of the hydantoin ... |
DB00980
|
Ramelteon |
C16H21NO2 |
259.3434 |
| ... Enoxacin Enoxacin increases levels/toxicity of ramelteon
Fluconazole This imidazole increases levels/toxicity of ramelteon
Fluvoxamine Fluvoxamine increases levels/toxicity of ramelteon ... |
DB00829
|
Diazepam |
C16H13ClN2O |
284.7400 |
| ... levels of the hydantoin, decrease of benzodiazepine
Fluconazole Fluconazole increases the effect of the benzodiazepine
Fosamprenavir Amprenavir increases the effect and toxicity of ... |
DB00897
|
Triazolam |
C17H12Cl2N4 |
343.2100 |
| ... levels of the hydantoin, decrease of benzodiazepine
Fluconazole Fluconazole increases the effect of the benzodiazepine
Fosamprenavir Amprenavir increases the effect and toxicity of ... |
DB00683
|
Midazolam |
C18H13ClFN3 |
325.7670 |
| ... levels of the hydantoin, decrease of benzodiazepine
Fluconazole Fluconazole increases the effect of benzodiazepine
Fosamprenavir Amprenavir increases the effect and toxicity of benzodiazepine ... |