| DrugBank ID |
Name |
Formula |
Weight |
DB00158
|
Folic Acid |
C19H19N7O6 |
441.3975 |
| ... Folic acid decreases the levels of hydantoin
Primidone Folic acid decreases the effect of anticonvulsant
Quinidine barbiturate Folic acid decreases the effect of anticonvulsant
Secobarbital ... |
DB00650
|
Leucovorin |
C20H23N7O7 |
473.4393 |
| ... favoring folic acid inhibition (following treatment of folic acid antagonists such as methotrexate). Leucovorin enhances the activity of fluorouracil by stabilizing the bond of the active ... |
DB00205
|
Pyrimethamine |
C12H13ClN4 |
248.7110 |
| ... Antagonists C12H13ClN4 Approved
Small Molecule One of the folic acid antagonists that is used as an antimalarial or with a sulfonamide to treat toxoplasmosis. [PubChem] Tablet Oral 00004774 ... |
DB00440
|
Trimethoprim |
C14H18N4O3 |
290.3177 |
| As folic acid is a coenzyme responsible for the transport of one-carbon fragments from one molecule to another, it is an essential component of bacterial development. Sulfonamides inhibit ... |
DB00627
|
Niacin |
C6H5NO2 |
123.1094 |
| ... Acid
NAH
Nicotine Acid
Nicotinic Acid
Pyridinecarboxylic Acid
Pyridylcarboxylic Acid
Vitamin B3
niacin Nicotinic acid can cause vasodilation of cutaneous blood vessels resulting in increased ... |
DB00126
|
Vitamin C |
C6H8O6 |
176.1241 |
| PA451898 25% 5785 597821 APRD00084
EXPT00568
NUTR00001 AA
Ascorbate
Ascorbic Acid
L-Ascorbate
L-Ascorbic Acid
L-Lyxoascorbic Acid
L-Xyloascorbic Acid 176.1241 176.0321 ... |
DB00563
|
Methotrexate |
C20H22N8O5 |
454.4393 |
| ... in the cell from folic acid with the help of an enzyme, folic acid reductase. Methotrexate looks a lot like folic acid to the enzyme, so it binds to it quite strongly and inhibits the enzyme ... |
DB02703
|
Fusidic Acid |
C31H48O6 |
516.7092 |
| Fucidin
Fucidin Cream 2%
Fucidin acid
Fucidine
Fucithalmic
Fusidine
Ramycin 6990-06-3 Anti-Bacterial Agents
Antibacterial Agents
Protein Synthesis Inhibitors C31H48O6 Approved
Small Molecule An ... |
DB00779
|
Nalidixic Acid |
C12H12N2O3 |
232.2353 |
| ... Nalidixan
Nalidixate
Nalidixic acid USP27
Nalidixin
Nalidixinic acid
Nalitucsan
Nalix
Nalurin
Naxuril
NegGram
Negram
Nevigramon
Nogram
Sicmylon
Unaserus
Urisal
Uronidix
Wintomylon
Wintron ... |
DB00116
|
Tetrahydrofolic acid |
C19H23N7O6 |
445.4292 |
| It is produced from dihydrofolic acid by dihydrofolate reductase.
It is converted into 5,10-methylenetetrahydrofolate by serine hydroxymethyltransferase. It is a coenzyme in many reactions ... |
DB00233
|
Aminosalicylic Acid |
C7H7NO3 |
153.1354 |
| As bacteria are unable to use external sources of folic acid, cell growth and multiplication slows. Secondly, aminosalicylic acid may inhibit the synthesis of the cell wall component, mycobactin ... |
DB00313
|
Valproic Acid |
C8H16O2 |
144.2114 |
| ... acid
Kyselina 2-propylvalerova
Myproic Acid
Propylvaleric acid
Sodium hydrogen divalproate
Valproate semisodique [French]
Valproate semisodium
Valproato semisodico [Spanish]
Valproatum ... |
DB01157
|
Trimetrexate |
C19H23N5O3 |
369.4176 |
| By interfering with the reduction of folic acid, trimetrexate interferes with tissue cell reproduction. Generally, the most sensitive cells to the antimetabolite effect of trimetrexate are those ... |
DB00945
|
Aspirin |
C9H8O4 |
180.1574 |
| ... acid
Acetylsalicylsaure (GERMAN)
Acetysalicylic acid
Acide acetylsalicylique (FRENCH)
Acido O-acetil-benzoico
Acido acetilsalicilico
Acidum acetylsalicylicum
Kyselina 2-acetoxybenzoova ... |
DB01586
|
Ursodeoxycholic acid |
C24H40O4 |
392.5720 |
| ... 7-beta-Hydroxylithocholic acid
7beta-Hydroxylithocholic acid
Acide ursodesoxycholique [inn-french]
Acido ursodeossicolico [italian]
Acido ursodeoxicolico [inn-spanish]
Acidum ursodeoxycholicum ... |
DB00548
|
Azelaic Acid |
C9H16O4 |
188.2209 |
| ... 2266 10460 APRD00812
EXPT00598 Anchoic acid
Azalaic Acid
Azelainic acid
Heptanedicarboxylic acid
Lepargylic acid
Nonanedioic acid
n-Nonanedioic acid Oral LD50 in rat: >5 g/kg 188.2209 188.1049 ... |
DB00939
|
Meclofenamic acid |
C14H11Cl2NO2 |
296.1490 |
| Meclofenamic acid Meclofenamic acid is a nonsteroidal agent which has demonstrated anti-inflammatory, analgesic, and antipyretic activity in laboratory animals. PA450341 Greater than 99% bound to ... |
DB00142
|
L-Glutamic Acid |
C5H9NO4 |
147.1293 |
| ... acid
2-Aminopentanedioic acid
Glutamic acid
Glutaminic acid
L-(+)-Glutamic acid
L-Glutamate
L-Glutaminic acid
L-a-Aminoglutaric acid
a-Aminoglutaric acid
a-Glutamic acid Glutamate causes ... |
DB01174
|
Phenobarbital |
C12H12N2O3 |
232.2353 |
| ... decreases the effect of the corticosteroid
Folic Acid Folic acid decreases the effect of anticonvulsant
Gefitinib This CYP3A4 inducer may reduce gefitinib plasma concentrations and ... |
DB01298
|
Sulfacytine |
C12H14N4O3S |
294.3300 |
| ... as competitive inhibitors of p-aminobenzoic acid in the folic acid metabolism cycle. Bacterial sensitivity is the same for the various sulfonamides, and resistance to one sulfonamide indicates ... |