| DrugBank ID |
Name |
Formula |
Weight |
DB00328
|
Indomethacin |
C19H16ClNO4 |
357.7880 |
| Indomethacin Indomethacin, a nonsteroidal antiinflammatory drug (NSAID) with analgesic and antipyretic properties, is used to treat osteoarthritis and control acute pain. PA449982 97% 3715 148696 ... |
DB00500
|
Tolmetin |
C15H15NO3 |
257.2845 |
| ... or osteaoarthritis, tolmetin is as effective as aspirin and indomethacin in controlling disease activity, but the frequency of the milder gastrointestinal adverse effects and tinnitus was less ... |
DB00465
|
Ketorolac |
C15H13NO3 |
255.2686 |
| ... pyrrolizine carboxylic acid derivative structurally related to indomethacin. It is an NSAID and is used principally for its analgesic activity. (From Martindale The Extra Pharmacopoeia, 31st ... |
DB00821
|
Carprofen |
C15H12ClNO2 |
273.7140 |
| ... analgesic and antipyretic activity approximately equipotent to indomethacin in animal models. High (99%) 2581 181659 APRD00849 2-(6-Chloro-9H-carbazol-2-yl)propanoic acid
6-Chloro-alpha-methyl ... |
DB01399
|
Salsalate |
C14H10O5 |
258.2262 |
| ... providing anti-inflammatory activity equivalent to aspirin and indomethacin. Unlike aspirin, salsalate does not inhibit platelet aggregation. Salsalate Salsalate is a nonsteroidal anti ... |
DB00678
|
Losartan |
C22H23ClN6O |
422.9110 |
| ... Drospirenone Increased risk of hyperkaliemia
Indomethacin Indomethacin decreases the effect of losartan
Lithium Losartan increases serum levels of lithium
Potassium Increased risk of ... |
DB00861
|
Diflunisal |
C13H8F2O3 |
250.1976 |
| ... effect
Indomethacin Increases the effect and toxicity of indomethacin
Probenecid Probenecid increases toxicity of diflunisal
Warfarin The NSAID increases the anticoagulant effect Avoid alcohol.
|
DB01032
|
Probenecid |
C13H19NO4S |
285.3590 |
| ... increases the effect and toxicity of ganciclovir/valganciclovir
Indomethacin Probenecid increases the effect/toxicity of indomethacin
Ketorolac Probenecid increases toxicity of ketorolac ... |
DB00887
|
Bumetanide |
C17H20N2O5S |
364.4160 |
| ... the diuretic and antihypertensive effects of the loop diuretic
Indomethacin The NSAID decreases the diuretic and antihypertensive effects of the loop diuretic
Kanamycin Increased ototoxicity ... |
DB00384
|
Triamterene |
C12H11N7 |
253.2626 |
| ... of hyperkaliemia
Fosinopril Increased risk of hyperkaliemia
Indomethacin Risk of acute renal impairment with this combination
Irbesartan Increased risk of hyperkaliemia
Lisinopril Increased ... |
DB00695
|
Furosemide |
C12H11ClN2O5S |
330.7440 |
| ... the diuretic and antihypertensive effects of the loop diuretic
Indomethacin The NSAID decreases the diuretic and antihypertensive effects of the loop diuretic
Kanamycin Increased ototoxicity ... |
DB00903
|
Ethacrynic acid |
C13H12Cl2O4 |
303.1380 |
| ... the diuretic and antihypertensive effects of the loop diuretic
Indomethacin The NSAID decreases the diuretic and antihypertensive effects of the loop diuretic
Kanamycin Increased ototoxicity ... |
DB00598
|
Labetalol |
C19H24N2O3 |
328.4055 |
| ... closely
Ibuprofen Risk of inhibition of renal prostaglandins
Indomethacin Risk of inhibition of renal prostaglandins
Insulin The beta-blocker decreases the symptoms of hypoglycemia
Isoflurane ... |
DB01203
|
Nadolol |
C17H27NO4 |
309.4006 |
| ... Ibuprofen Risk of inhibition of renal prostaglandins
Indomethacin Risk of inhibition of renal prostaglandins
Insulin The beta-blocker decreases the symptoms of hypoglycemia
Isoproterenol ... |
DB01580
|
Oxprenolol |
C15H23NO3 |
265.3480 |
| ... Ibuprofen Risk of inhibition of renal prostaglandins
Indomethacin Risk of inhibition of renal prostaglandins
Insulin The beta-blocker decreases the symptoms of hypoglycemia
Isoproterenol ... |
DB00440
|
Trimethoprim |
C14H18N4O3 |
290.3177 |
| Indomethacin The strong CYP2C9 inhibitor, Indomethacine, may decrease the metabolism and clearance of Trimethoprim, a CYP2C9 substrate. Consider alternate therapy or monitor for changes in ... |
DB00373
|
Timolol |
C13H24N4O3S |
316.4200 |
| The NSAID, Indomethacine, may also antagonize the antihypertensive effect of Timolol.
Insulin The beta-blocker decreases the symptoms of hypoglycemia
Isoproterenol Antagonism
Ketoprofen The NSAID ... |
DB00214
|
Torasemide |
C16H20N4O3S |
348.4200 |
| ... changes in the therapeutic and adverse effects of Torasemide if Indomethacin is initiated, discontinued or dose changed.
Ketoconazole Ketoconazole, a strong CYP2C9 inhibitor, may increase the ... |
DB00960
|
Pindolol |
C14H20N2O2 |
248.3208 |
| ... Ibuprofen Risk of inhibition of renal prostaglandins
Indomethacin Risk of inhibition of renal prostaglandins
Insulin The beta-blocker decreases the symptoms of hypoglycemia
Isoproterenol ... |
DB00187
|
Esmolol |
C16H25NO4 |
295.3740 |
| ... Ibuprofen Risk of inhibition of renal prostaglandins
Indomethacin Risk of inhibition of renal prostaglandins
Insulin The beta-blocker decreases the symptoms of hypoglycemia
Insulin-aspart The ... |