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Search for "Lovastatin" returned 34 results

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DrugBank ID	Name	Formula	Weight
DB00227	Lovastatin	C24H36O5	404.5396
	Lovastatin Lovastatin Pathway SMP00099 Lovastatin, an antilipemic agent produced by fermentation of <i>Aspergillus terreus</i>, is the first of a class of lipid-lowering agents known as the HMG ...
DB00641	Simvastatin	C25H38O5	418.5662
	... Ezetimibe) Simvastatin Simvastatin, the methylated form of lovastatin, is an oral antilipemic agent which inhibits HMG-CoA reductase. simvastatin is used in the treatment of primary ...
DB00175	Pravastatin	C23H36O7	424.5277
	... 1-yl]-3,5-dihydroxyheptanoic acid C01844 Like lovastatin and simvastatin, pravastatin inhibits hydroxymethylglutaryl-CoA (HMG-CoA) reductase. As HMG-CoA is necessary for the intracellular ...
DB01095	Fluvastatin	C24H26FNO4	411.4659
	Although similar to lovastatin, simvastatin, and pravastatin, Fluvastatin has a shorter half-life, no active metabolites, extensive protein binding, and minimal CSF penetration. PA449688 98 ...
DB00207	Azithromycin	C38H72N2O12	748.9845
	... Disopyramide The macrolide increases the effect of disopyramide Lovastatin Azithromycin can possibly increase the statin toxicity Warfarin Increases the anticoagulant effect Do not take ...
DB00238	Nevirapine	C15H14N4O	266.2979
	... effect Ketoconazole Decreases the effect of ketoconazole Lovastatin The NNRT inhibitor increases the effect and toxicity of the statin Methadone The antiretroviral agent decreases the effect ...
DB01241	Gemfibrozil	C15H22O3	250.3334
	... effect Fluvastatin Increased risk of myopathy/rhabdomyolysis Lovastatin Increased risk of myopathy/rhabdomyolysis Pioglitazone Increases the effect and toxicity of rosiglitazone/pioglitazone ...
DB01406	Danazol	C22H27NO2	337.4553
	... Dicumarol The androgen increases the anticoagulant effect Lovastatin Risk of severe myopathy/rhabdomyolysis with this combination Tacrolimus Increases the effect and toxicity of tacrolimus ...
DB01039	Fenofibrate	C20H21ClO4	360.8310
	... effect Fluvastatin Increased risk of myopathy/rhabdomyolysis Lovastatin Increased risk of myopathy/rhabdomyolysis Pravastatin Increased risk of myopathy/rhabdomyolysis Rosuvastatin ...
DB00627	Niacin	C6H5NO2	123.1094
	It is indicated as ajunctive therapy. Lovastatin Risk of severe myopathy/rhabdomyolysis with this combination Avoid alcohol. Take with food. pyridine-3-carboxylic acid C00253 D00049 Niacin binds ...
DB01394	Colchicine	C22H25NO6	399.4370
	... Increased risk of rhabdomyolysis with this combination Lovastatin Increased risk of rhabdomyolysis with this combination Pravastatin Increased risk of rhabdomyolysis with this combination ...
DB00559	Bosentan	C27H29N5O6S	551.6140
	... This imidazole increases the effect and toxicity of bosentan Lovastatin Bosentan could decrease the statin effect Medroxyprogesterone Decreases the effect of contraceptive Mestranol Decreases ...
DB00343	Diltiazem	C22H26N2O4S	414.5180
	... barbiturate Increases the effect and toxicity of quinidine Lovastatin Increases the effect and toxicity of the statin Mesoridazine Increased risk of cardiotoxicity and arrhythmias Metoprolol ...
DB00625	Efavirenz	C14H9ClF3NO2	315.6750
	... toxicity Indinavir Efavirenz decreases the effect of indinavir Lovastatin The NNRT inhibitor increases the effect and toxicity of the statin Methadone The antiretroviral agent decreases the ...
DB00619	Imatinib	C29H31N7O	493.6027
	... Ketoconazole The imidazole increases the levels of imatinib Lovastatin Imatinib increases the effect and toxicity of statin Mephenytoin The hydantoin decreases the levels of imatinib ...
DB00705	Delavirdine	C22H28N6O3S	456.5610
	... of delavirdine Indinavir Increases the effect of indinavir Lovastatin The NNRT inhibitor increases the effect and toxicity of the statin Magnesium The antiacid decreases the effect of ...
DB00661	Verapamil	C27H38N2O4	454.6016
	Avoid concurrent use if possible or reduce lovastatin dose during concomitant therapy. Monitor for changes in the therapeutic/adverse effects of Lovastatin if Verapamil is initiated, discontinued ...
DB01149	Nefazodone	C25H32ClN5O2	470.0070
	... syndrome Loratadine Increased risk of cardiotoxicity Lovastatin Nefazodone increases the effect and toxicity of the statin drug Naratriptan Increased risk of CNS adverse effects Phenelzine ...
DB00196	Fluconazole	C13H12F2N6O	306.2708
	... imidazole increases the effect and toxicity of the tricyclic Lovastatin Increased risk of myopathy/rhabdomyolysis Mephenytoin Increases the effect of hydantoin Midazolam Increases the effect ...
DB00615	Rifabutin	C46H62N4O11	847.0047
	... Josamycin The rifamycin decreases the effect of the macrolide Lovastatin The rifamycin decreases the effect of the statin drug Mestranol This product may cause a slight decrease of the ...

Showing 1-20 out of 34

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This project is supported by Genome Alberta & Genome Canada, a not-for-profit organization that is leading Canada's national genomics strategy with $600 million in funding from the federal government. This project is also supported in part by GenomeQuest, Inc., an enterprise genomic information company serving the life science community.