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Search for "Methotrexate" returned 48 results

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Showing 1-20 out of 48

DrugBank ID	Name	Formula	Weight
DB00563	Methotrexate	C20H22N8O5	454.4393
	... levels of methotrexate Ciprofloxacin Ciprofloxacin increases methotrexate toxicity Cisplatin Cisplatin increases methotrexate toxicity Cloxacillin The penicillin increases the effect and ...
DB00650	Leucovorin	C20H23N7O7	473.4393
	... therapeutic and toxic effects of folic acid antagonists such as methotrexate, which act by inhibiting dihydrofolate reductase. Leucovorin has also been used to enhance the activity of ...
DB01401	Trisalicylate-choline
	Trisalicylate significantly reduces methotrexate renal clearance, displacing methotrexate from protein, increasing the fraction unbound by 28%.(PMID: 1728115, 1618240) DB01401 Trisalicylate ...
DB01281	Abatacept		92000.0000
	... more disease-modifying anti-rheumatic drugs (DMARDs), such as methotrexate or TNF antagonists. It is indicated both as a monotherapy and for use in combination with a continued regimen of ...
DB00469	Tenoxicam	C13H11N3O4S2	337.3740
	Monitor for changes in Methotrexate therapeutic and adverse effects if Tenoxicam is initiated, discontinued or dose changed. Metolazone Tenoxicam may antagonize the blood pressure lowering effect ...
DB00749	Etodolac	C17H21NO3	287.3535
	... Methotrexate The NSAID increases the effect and toxicity of methotrexate Warfarin The NSAID increases the anticoagulant effect Avoid alcohol. Take with food. 2-(1,8-diethyl-4,9-dihydro-3H ...
DB01604	Pivampicillin	C22H29N3O6S	463.5470
	... The penicillin increases the effect and toxicity of methotrexate Minocycline Possible antagonism of action Oxytetracycline Possible antagonism of action Rolitetracycline Possible antagonism of ...
DB00301	Flucloxacillin	C19H17ClFN3O5S	453.8720
	... oral contraceptive Methacycline Possible antagonism of action Methotrexate The penicillin increases the effect and toxicity of methotrexate Minocycline Possible antagonism of action ...
DB00459	Acitretin	C21H26O3	326.4293
	... Methacycline Increased risk of intracranial hypertension Methotrexate Acitretin/etretinate increases the effect and toxicity of methotrexate Minocycline Increased risk of intracranial ...
DB00461	Nabumetone	C15H16O2	228.2863
	... Dicumarol The NSAID increases the anticoagulant effect Methotrexate The NSAID increases the effect and toxicity of methotrexate Warfarin The NSAID increases the anticoagulant effect Avoid alcohol.
DB00485	Dicloxacillin	C19H17Cl2N3O5S	470.3260
	... The penicillin increases the effect and toxicity of methotrexate Minocycline Possible antagonism of action Oxytetracycline Possible antagonism of action Rolitetracycline Possible antagonism of ...
DB00527	Dibucaine	C20H29N3O2	343.4632
	... effect Lithium The NSAID increases serum levels of lithium Methotrexate The NSAID increases the effect and toxicity of methotrexate 2-butoxy-N-(2-diethylaminoethyl)quinoline-4-carboxamide ...
DB00712	Flurbiprofen	C15H13FO2	244.2609
	... Methotrexate The NSAID increases the effect and toxicity of methotrexate Warfarin The NSAID increases the anticoagulant effect Avoid alcohol. Take with food to reduce irritation. 2-(3-fluoro-4 ...
DB00766	Clavulanate	C8H9NO5	199.1608
	... oral contraceptive Methacycline Possible antagonism of action Methotrexate The penicillin increases the effect and toxicity of methotrexate Minocycline Possible antagonism of action ...
DB00784	Mefenamic acid	C15H15NO2	241.2851
	... Methotrexate The NSAID increases the effect and toxicity of methotrexate Warfarin The NSAID increases the anticoagulant effect Avoid alcohol. Take with food. 2-[(2,3-dimethylphenyl)amino ...
DB00991	Oxaprozin	C18H15NO3	293.3166
	... Dicumarol The NSAID increases the anticoagulant effect Methotrexate The NSAID increases the effect and toxicity of methotrexate Warfarin The NSAID increases the anticoagulant effect Take with ...
DB01009	Ketoprofen	C16H14O3	254.2806
	... Methotrexate The NSAID increases the effect and toxicity of methotrexate Warfarin The NSAID increases the anticoagulant effect Take with food to reduce irritation, avoid alcohol. 2-[3-(benzoyl ...
DB01147	Cloxacillin	C19H18ClN3O5S	435.8810
	... The penicillin increases the effect and toxicity of methotrexate Minocycline Possible antagonism of action Oxytetracycline Possible antagonism of action Rolitetracycline Possible antagonism of ...
DB00415	Ampicillin	C16H19N3O4S	349.4050
	... oral contraceptive Methacycline Possible antagonism of action Methotrexate The penicillin increases the effect and toxicity of methotrexate Minocycline Possible antagonism of action ...
DB00465	Ketorolac	C15H13NO3	255.2686
	... effect Lithium The NSAID increases serum levels of lithium Methotrexate The NSAID increases the effect and toxicity of methotrexate Probenecid Probenecid increases toxicity of ketorolac ...

Showing 1-20 out of 48

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This project is supported by Genome Alberta & Genome Canada, a not-for-profit organization that is leading Canada's national genomics strategy with $600 million in funding from the federal government. This project is also supported in part by GenomeQuest, Inc., an enterprise genomic information company serving the life science community.