| DrugBank ID |
Name |
Formula |
Weight |
DB00220
|
Nelfinavir |
C32H45N3O4S |
567.7820 |
| Nelfinavir Nelfinavir is a protease inhibitor with activity against Human Immunodeficiency Virus Type 1 (HIV-1). Protease inhibitors block the part of HIV called protease. HIV-1 protease is an ... |
DB00932
|
Tipranavir |
C31H33F3N2O5S |
602.6640 |
| Nelfinavir binds to the protease active site and inhibits the activity of the enzyme. This inhibition prevents cleavage of the viral polyproteins resulting in the formation of immature non ... |
DB00238
|
Nevirapine |
C15H14N4O |
266.2979 |
| ... The antiretroviral agent decreases the effect of methadone
Nelfinavir Decreases the effect of nelfinavir
Quinupristin This combination presents an increased risk of toxicity
Saquinavir ... |
DB01023
|
Felodipine |
C18H19Cl2NO4 |
384.2540 |
| ... The barbiturate decreases the effect of felodipine
Nelfinavir Nelfinavir increases the effect and toxicity of felodipine
Oxcarbazepine Oxcarbazepine decreases the levels of felodipine ... |
DB01100
|
Pimozide |
C28H29F2N3O |
461.5462 |
| ... increases the effect and toxicity of pimozide
Nelfinavir Nelfinavir increases the effect and toxicity of pimozide
Paroxetine Increased risk of cardiotoxicity/arrhythmias
Posaconazole ... |
DB00496
|
Darifenacin |
C28H30N2O2 |
426.5500 |
| ... CYP3A4 inhibitor slows darifenacin/solifenacin metabolism
Nelfinavir This potent CYP3A4 inhibitor slows darifenacin/solifenacin metabolism
Ritonavir This potent CYP3A4 inhibitor slows ... |
DB01410
|
Ciclesonide |
C32H44O7 |
540.6876 |
| ... Ketoconazole Increased effects/toxicity of ciclesonide
Nelfinavir Increased effects/toxicity of ciclesonide
Ritonavir Increased effects/toxicity of ciclesonide D01703 Glucocorticoids such as ... |
DB02703
|
Fusidic Acid |
C31H48O6 |
516.7092 |
| ... Indinavir increases the effect and toxicity of fusidic acid
Nelfinavir The protease inhibitor increases the effect and toxicity of fusidic acid
Ritonavir The protease inhibitor increases the ... |
DB00690
|
Flurazepam |
C21H23ClFN3O |
387.8780 |
| ... increased levels of the hydantoin, decrease of benzodiazepine
Nelfinavir The protease inhibitor increases the effect of the benzodiazepine
Omeprazole Omeprazole increases the effect of ... |
DB01068
|
Clonazepam |
C15H10ClN3O3 |
315.7110 |
| ... The imidazole increases the effect of the benzodiazepine
Nelfinavir The protease inhibitor increases the effect of the benzodiazepine
Omeprazole Omeprazole increases the effect of ... |
DB00227
|
Lovastatin |
C24H36O5 |
404.5396 |
| ... Nefazodone increases the effect and toxicity of the statin
Nelfinavir Nelfinavir increases the effect and toxicity of the statin
Nevirapine The NNRT inhibitor increases the effect and toxicity ... |
DB00333
|
Methadone |
C21H27NO |
309.4452 |
| ... withdrawal syndrome in opioid-dependent individuals
Nelfinavir Nelfinavir decreases the effect of methadone
Nevirapine The antiretroviral agent decreases the effect of methadone
Pentobarbital ... |
DB01076
|
Atorvastatin |
C33H35FN2O5 |
558.6398 |
| ... increases the effect and toxicity of the statin drug
Nelfinavir Nelfinavir increases the effect and toxicity of the statin
Nevirapine The NNRT inhibitor increases the effect and toxicity of ... |
DB00475
|
Chlordiazepoxide |
C16H14ClN3O |
299.7550 |
| ... increased levels of the hydantoin, decrease of benzodiazepine
Nelfinavir The protease inhibitor increases the effect of the benzodiazepine
Omeprazole Omeprazole increases the effect of ... |
DB00530
|
Erlotinib |
C22H23N3O4 |
393.4357 |
| ... This CYP3A4 inhibitor increases levels/toxicity of erlotinib
Nelfinavir This CYP3A4 inhibitor increases levels/toxicity of erlotinib
Rifabutin Decreased levels/effect of erlotinib
Rifampin ... |
DB00628
|
Clorazepate |
C16H11ClN2O3 |
314.7230 |
| ... increased levels of the hydantoin, decrease of benzodiazepine
Nelfinavir The protease inhibitor increases the effect of the benzodiazepine
Omeprazole Omeprazole increases the effect of ... |
DB00813
|
Fentanyl |
C22H28N2O |
336.4705 |
| ... a withdrawal syndrome in opioid-dependent individuals
Nelfinavir The protease inhibitor increases the effect and toxicity of fentanyl
Rifampin Rifampin reduces levels and efficacy of fentanyl ... |
DB01215
|
Estazolam |
C16H11ClN4 |
294.7380 |
| ... increased levels of the hydantoin, decrease of benzodiazepine
Nelfinavir The protease inhibitor increases the effect of the benzodiazepine
Omeprazole Omeprazole increases the effect of ... |
DB00320
|
Dihydroergotamine |
C33H37N5O5 |
583.6774 |
| ... Possible ergotism and severe ischemia with this combination
Nelfinavir Nelfinavir increases the effect and toxicity of ergot derivative
Nitroglycerin Possible antagonism of action
Oxprenolol ... |
DB00696
|
Ergotamine |
C33H35N5O5 |
581.6615 |
| ... ergotism and severe ischemia with this combination
Nelfinavir Nelfinavir increases the effect and toxicity of ergot derivative
Nitroglycerin Possible antagonism of action
Oxprenolol Ischemia ... |