Search Results
Search for "Pravastatin" returned 8 results
Showing 1-8 out of 8
| DrugBank ID |
Name |
Formula |
Weight |
DB00175
|
Pravastatin |
C23H36O7 |
424.5277 |
| Unlike lovastatin and simvastatin, pravastatin is relatively hydrophilic and does not require hydrolysis for activation. PA451089 50% 54687 192211 APRD00328 Pravastatin Sodium
Pravastatina ... |
DB01095
|
Fluvastatin |
C24H26FNO4 |
411.4659 |
| Although similar to lovastatin, simvastatin, and pravastatin, Fluvastatin has a shorter half-life, no active metabolites, extensive protein binding, and minimal CSF penetration. PA449688 98 ... |
DB01241
|
Gemfibrozil |
C15H22O3 |
250.3334 |
| ... Increases the effect and toxicity of rosiglitazone/pioglitazone
Pravastatin Increased risk of myopathy/rhabdomyolysis
Repaglinide Increases the effect and toxicity of repaglinide
Rosiglitazone ... |
DB00227
|
Lovastatin |
C24H36O5 |
404.5396 |
| Lovastatin, like simvastin and unlike pravastatin, is a prodrug, concentrating active drug in the liver during first-pass circulation. PA450272 >95% 53232 191104 APRD00370 6 alpha-Methylcompactin ... |
DB01039
|
Fenofibrate |
C20H21ClO4 |
360.8310 |
| ... Lovastatin Increased risk of myopathy/rhabdomyolysis
Pravastatin Increased risk of myopathy/rhabdomyolysis
Rosuvastatin Rosuvastatin possibly increases the effect of the fibrate
Simvastatin ... |
DB01394
|
Colchicine |
C22H25NO6 |
399.4370 |
| ... Increased risk of rhabdomyolysis with this combination
Pravastatin Increased risk of rhabdomyolysis with this combination
Rosuvastatin Increased risk of rhabdomyolysis with this combination ... |
DB00932
|
Tipranavir |
C31H33F3N2O5S |
602.6640 |
| Pravastatin Tipranavir may increase the plasma concentration of Pravastatin. Consider alternate therapy.
Prazepam Tipranavir may decrease the metabolism and clearance of Prazepam. Consider ... |
DB00091
|
Cyclosporine |
C62H111N11O12 |
1202.6112 |
| ... for nephrotoxicity
Posaconazole Increased level of cyclosporine
Pravastatin Possible myopathy and rhabdomyolysis
Primidone The barbiturate increases the effect of cyclosporine
Probucol ... |
Showing 1-8 out of 8