| DrugBank ID |
Name |
Formula |
Weight |
DB00503
|
Ritonavir |
C37H48N6O5S2 |
720.9440 |
| Kaletra (Lopinavir + Ritonavir) Ritonavir Ritonavir is a protease inhibitor with activity against Human Immunodeficiency Virus Type 1 (HIV-1). Protease inhibitors block the part of HIV called ... |
DB01264
|
Darunavir |
C27H37N3O7S |
547.6640 |
| CJBJHOAVZSMMDJ-QSHSPGAWDK Darunavir, co-administered with ritonavir, and with other antiretroviral agents, is indicated for the treatment of human immunodeficiency virus (HIV) infection in ... |
DB01601
|
Lopinavir |
C37H48N4O5 |
628.8008 |
| Kaletra (Lopinavir + Ritonavir) Lopinavir Lopinavir is an antiretroviral of the protease inhibitor class. PA450264 Lopinavir is highly bound to plasma proteins (98-99%). 92727 10225535 EXPT00388 ... |
DB00932
|
Tipranavir |
C31H33F3N2O5S |
602.6640 |
| Flecainide Tipranavir, co-administered with Ritonavir, may increase the plasma concentration of Flecainide. Concomitant therapy is contraindicated.
Fluconazole Fluconazole may increase the serum ... |
DB01141
|
Micafungin |
C56H71N9O23S |
1270.2740 |
| ... a variety of other drugs, including the HIV protease inhibitor ritonavir and the transplant medications cyclosporine and tacrolimus. Highly (>99%) protein bound in vitro, independent of plasma ... |
DB00334
|
Olanzapine |
C17H20N4S |
312.4320 |
| ... of olanzapine
Galantamine Possible antagonism of action
Ritonavir Ritonavir decreases the effect of olanzapine
Rivastigmine Possible antagonism of action Avoid alcohol.
Take without regard to ... |
DB00346
|
Alfuzosin |
C19H27N5O4 |
389.4488 |
| ... The antifungal increases the effect of alfuzosin
Ritonavir Ritonavir increases the effect/toxicity of alfuzosin
Vardenafil Risk of significant hypotension with this association Take after a ... |
DB00358
|
Mefloquine |
C17H16F6N2O |
378.3122 |
| ... of cardiac toxicity
Rifampin Rifampin lowers mefloquine levels
Ritonavir Mefloquine decreases the effect of ritonavir
Warfarin Mefloquine can increase the anticoagulant effect
Ziprasidone ... |
DB00647
|
Propoxyphene |
C22H29NO2 |
339.4712 |
| ... a withdrawal syndrome in opioid-dependent individuals
Ritonavir Ritonavir increases the levels of analgesic
Warfarin Propoxyphene increases the anticoagulant effect Take without regard to meals. |
DB01156
|
Bupropion |
C13H18ClNO |
239.7410 |
| ... levels
Rifampin Rifampin reduces bupropion levels
Ritonavir Ritonavir increases the effect and toxicity of bupropion
Thioridazine Inceases the effect and toxicity of thioridazine ... |
DB01195
|
Flecainide |
C17H20F6N2O3 |
414.3427 |
| ... combination presents an increased risk of toxicity
Ritonavir Ritonavir increases the toxicity of the anti-arrhythmic
Terfenadine Increased risk of cardiotoxicity and arrhythmias
Thioridazine ... |
DB01244
|
Bepridil |
C24H34N2O |
366.5396 |
| ... Increased risk of cardiotoxicity and arrhythmias
Ritonavir Ritonavir increases the effect and toxicity of bepridil
Sparfloxacin Increased risk of cardiotoxicity and arrhythmias
Terfenadine ... |
DB00454
|
Meperidine |
C15H21NO2 |
247.3327 |
| ... effects
Rasagiline Potentially fatal adverse effects
Ritonavir Ritonavir increases the levels of analgesic
Rivastigmine Possible antagonism of action
Selegiline Potentially fatal adverse ... |
DB00490
|
Buspirone |
C21H31N5O2 |
385.5031 |
| ... Rifampin Rifampin decreases the effect of buspirone
Ritonavir Ritonavir increases the effect and toxicity of buspirone
Tranylcypromine Possible blood pressure elevation
Verapamil The calcium ... |
DB00813
|
Fentanyl |
C22H28N2O |
336.4705 |
| ... reduces levels and efficacy of fentanyl/alfentanyl
Ritonavir Ritonavir increases the effect and toxicity of fentanyl/alfentanyl
Saquinavir The protease inhibitor increases the effect and ... |
DB00554
|
Piroxicam |
C15H13N3O4S |
331.3460 |
| ... Risk of inhibition of renal prostaglandins
Ritonavir Ritonavir increases the toxicity of piroxicam
Sotalol Risk of inhibition of renal prostaglandins
Timolol Risk of inhibition of renal ... |
DB00343
|
Diltiazem |
C22H26N2O4S |
414.5180 |
| ... of toxicity
Rifampin Rifampin decreases levels of diltiazem
Ritonavir Ritonavir increases diltiazem levels
Simvastatin Increases the effect and toicity of simvastatin
Sirolimus Increases the ... |
DB00300
|
Tenofovir |
C9H14N5O4P |
287.2123 |
| Concomitant therapy should only be used with the inclusion of Ritonavir.
Didanosine Tenofovir may decrease the therapeutic effects and increase the adverse effects of Didanosine. Monitor for ... |
DB00496
|
Darifenacin |
C28H30N2O2 |
426.5500 |
| ... CYP3A4 inhibitor slows darifenacin/solifenacin metabolism
Ritonavir This potent CYP3A4 inhibitor slows darifenacin/solifenacin metabolism
Rivastigmine Possible antagonism of action Take ... |
DB01410
|
Ciclesonide |
C32H44O7 |
540.6876 |
| ... Nelfinavir Increased effects/toxicity of ciclesonide
Ritonavir Increased effects/toxicity of ciclesonide D01703 Glucocorticoids such as ciclesonide can inhibit leukocyte infiltration at the ... |